Author details

Full Name

Alex J Kuo

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36571819	Mass-Cytometry-Based Quantification of Global Histone Post-Translational Modifications at Single-Cell Resolution Across Peripheral Immune Cells in IBD.	J Crohns Colitis	2023
37606045	Ancestry-based differences in the immune phenotype are associated with lupus activity.	JCI Insight	2023
34521836	New-onset IgG autoantibodies in hospitalized patients with COVID-19.	Nat Commun	2021
34017121	Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation.	Nat Immunol	2021
34174187	The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination.	Cell	2021
33532787	New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19.	medRxiv	2021
31065108	Single-cell technologies - studying rheumatic diseases one cell at a time.	Nat Rev Rheumatol	2019
29706550	Single-Cell Chromatin Modification Profiling Reveals Increased Epigenetic Variations with Aging.	Cell	2018
29960011	Single-cell epigenetics - Chromatin modification atlas unveiled by mass cytometry.	Clin Immunol	2018
28018971	Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity.	JCI Insight	2016
25128496	A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.	Genes Dev	2014
23318260	Chd5 requires PHD-mediated histone 3 binding for tumor suppression.	Cell Rep	2013
22398447	The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.	Nature	2012
22099308	NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.	Mol Cell	2011
21131967	Lysine methylation of the NF-ÎºB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-ÎºB signaling.	Nat Immunol	2011
20452361	Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription.	J Mol Biol	2010
19808676	The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.	J Biol Chem	2009
19184981	NMR assignments and histone specificity of the ING2 PHD finger.	Magn Reson Chem	2009
19187765	ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.	Mol Cell	2009
19884654	Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages.	Journal of Clinical Investigation	2009
19956676	Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks.	PLoS One	2009
18533182	Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.	J Mol Biol	2008
18840680	Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.	Proc Natl Acad Sci U S A	2008
18025461	The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2.	Proc Natl Acad Sci U S A	2007
18033247	RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.	Nature	2007