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Author Details

Juha T Huiskonen
Institute of Biotechnology, University of Helsinki
2002
79
35
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36739529MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α.Cell Rep2023
37699397Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity.Mol Cell2023
37169961Signal peptide mimicry primes Sec61 for client-selective inhibition.Nat Chem Biol2023
36964125Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants.Nat Commun2023
36586407Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms.Cell Rep2023
34774568Structure of a Cell Entry Defective Human Adenovirus Provides Insights into Precursor Proteins and Capsid Maturation.J Mol Biol2022
35705539Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.Nat Commun2022
35449234Snapshots of actin and tubulin folding inside the TRiC chaperonin.Nat Struct Mol Biol2022
36463224Cryo-EM structure of ssDNA bacteriophage ΦCjT23 provides insight into early virus evolution.Nat Commun2022
36111986Mechanistic Insights into the Activation of Lecithin-Cholesterol Acyltransferase in Therapeutic Nanodiscs Composed of Apolipoprotein A-I Mimetic Peptides and Phospholipids.Mol Pharm2022
32470354Localized reconstruction in Scipion expedites the analysis of symmetry mismatches in cryo-EM data.Prog Biophys Mol Biol2021
34225492Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen.mBio2021
32937107The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.Cell2020
33349334Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.Elife2020
30783086The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.Nat Commun2019
31684117Assessment of Immunogenicity and Efficacy of a Zika Vaccine Using Modified Vaccinia Ankara Virus as Carriers.Pathogens2019
31522708Structures of enveloped virions determined by cryogenic electron microscopy and tomography.Adv Virus Res2019
31477691The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.Nat Commun2019
30926810Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.Nat Commun2019
31014919Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways.Prog Biophys Mol Biol2019
31142835Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus.Nature2019
29367607Shielding and activation of a viral membrane fusion protein.Nat Commun2018
29973616Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils.Sci Rep2018
29941589Structure of the Lassa virus glycan shield provides a model for immunological resistance.Proc Natl Acad Sci U S A2018
30096461Beyond structures of highly symmetric purified viral capsids by cryo-EM.Curr Opin Struct Biol2018
30323338Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus.Nat Immunol2018
30590046A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus.Cell Rep2018
30279282Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly.mBio2018
29491457Towards in cellulo virus crystallography.Sci Rep2018
29439140Image processing for cryogenic transmission electron microscopy of symmetry-mismatched complexes.Biosci Rep2018
27991905Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).Nat Struct Mol Biol2017
28446752Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability.Nat Commun2017
28287099Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.Nat Commun2017
28092368Molecular insights into lipid-assisted Ca<sup>2+</sup> regulation of the TRP channel Polycystin-2.Nat Struct Mol Biol2017
29127347Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging.Nat Commun2017
28937999Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.PLoS Pathog2017
28835498Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope.J Virol2017
28534487Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus.Nat Commun2017
28716906Virus found in a boreal lake links ssDNA and dsDNA viruses.Proc Natl Acad Sci U S A2017
28682240Building bridges between cellular and molecular structural biology.Elife2017
26811337Low pH and Anionic Lipid-dependent Fusion of Uukuniemi Phlebovirus to Liposomes.J Biol Chem2016
27355863A Molecular-Level Account of the Antigenic Hantaviral Surface.Cell Rep2016
27117403A Molecular-Level Account of the Antigenic Hantaviral Surface.Cell Rep2016
27325770Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion.Proc Natl Acad Sci U S A2016
27521688Editorial overview: Virus structure and assembly: Virions - from structure and physics to design principles.Curr Opin Virol2016
26880565Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein.Elife2016
26849049Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike.PLoS Pathog2016
26169737Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility.Methods Mol Biol2015
26534841Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes.Nat Commun2015
26389739Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.Nat Struct Mol Biol2015
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Collaborators

David I Stuart
University of Oxford
Co-authored papers 11
Kay Gr??newald
Leibniz Institute of Virology
Co-authored papers 7
Tobias C Walther
Harvard T. H. Chan School of Public Health
Co-authored papers 2
Natasza E Zi????kowska
Tonix Pharmaceuticals Inc
Co-authored papers 2
Frank DiMaio
University of Washington
Co-authored papers 2
Lena Karotki
Max Planck Institute of Biochemistry
Co-authored papers 2
Zihe Rao
Nankai University
Co-authored papers 2
Janet L Anderl
Onyx Pharmaceuticals, Inc.
Co-authored papers 1
Andrii Iudin
Co-authored papers 1
Paola Picotti
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Jason R Swedlow
University of Dundee
Co-authored papers 1
Dan H Barouch
Co-authored papers 1
Michael Rehman
Institute of Biochemistry, Friedrich-Alexander-University of Erlangen-Nurnberg
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Phillip P Sharp
University of California san francisco
Co-authored papers 1
Nicole A Wenzell
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Arun Prasad Pandurangan
Co-authored papers 1
Georg Kochs
Institute of Virology, Freiburg University Medical Center, University of Freiburg
Co-authored papers 1
Scott D Emr
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 1
Sirarat Sarntivijai
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 1
Jack Taunton
University of California san francisco
Co-authored papers 1
Helen Parkinson
European Bioinformatics Institute
Co-authored papers 1
Ilinca Tudose
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 1
Tom L Blundell
Heartand Lung Research Institute, University of Cambridge
Co-authored papers 1
Maya Topf
Leibniz-Institut fur Virologie (LIV)
Co-authored papers 1
John E Heuser
Washington University School of Medicine
Co-authored papers 1
Peter B Rosenthal
The Francis Crick Institute
Co-authored papers 1
Christopher J Stefan
University College London
Co-authored papers 1
Michal A Surma
Lukasiewicz Research Network-PORT Polish Center for Technology Development
Co-authored papers 1
Robyn Roth
Washington University School of Medicine
Co-authored papers 1
Release 1.2