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Author Details
Full Name
Coert J Zuurbier
Affiliation
University Medical Centers
ORCID
Career Start Year
1991
Papers
116
H Index
40
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
38061206
Empagliflozin prevents oxidative stress in human coronary artery endothelial cells via the NHE/PKC/NOX axis.
Redox Biol
2024
36649392
Sodium Glucose Cotransporter-2 Inhibitor Empagliflozin Reduces Infarct Size Independently of Sodium Glucose Cotransporter-2.
Circulation
2023
37565139
Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells.
Front Physiol
2023
37408266
Pharmacological Cardioprotection against Ischemia Reperfusion Injury-The Search for a Clinical Effective Therapy.
Cells
2023
36753049
Interaction of Cardiovascular Nonmodifiable Risk Factors, Comorbidities and Comedications With Ischemia/Reperfusion Injury and Cardioprotection by Pharmacological Treatments and Ischemic Conditioning.
Pharmacol Rev
2023
36623448
Canagliflozin inhibits inflammasome activation in diabetic endothelial cells - Revealing a novel calcium-dependent anti-inflammatory effect of canagliflozin on human diabetic endothelial cells.
Biomed Pharmacother
2023
36718529
Cardioprotective efficacy of limb remote ischaemic preconditioning in rats: discrepancy between a meta-analysis and a three-centre in vivo study.
Cardiovasc Res
2023
34896968
Empagliflozin reduces oxidative stress through inhibition of the novel inflammation/NHE/[Na<sup>+</sup>]<sub>c</sub>/ROS-pathway in human endothelial cells.
Biomed Pharmacother
2022
35581445
Cardioprotection by selective SGLT-2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?
Basic Res Cardiol
2022
35393687
Amelioration of endothelial dysfunction by sodium glucose co-transporter 2 inhibitors: pieces of the puzzle explaining their cardiovascular protection.
Br J Pharmacol
2022
35894858
Use of sodium-glucose cotransporter-2 inhibitors and the risk for sudden cardiac arrest and for all-cause death in patients with type 2 diabetes mellitus.
Eur Heart J Cardiovasc Pharmacother
2022
35331696
Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects.
J Mol Cell Cardiol
2022
35303888
Direct cardiac effects of SGLT2 inhibitors.
Cardiovasc Diabetol
2022
32295413
Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative Stress.
Antioxid Redox Signal
2021
33792689
Sodium-glucose co-transporter 2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions.
Cardiovasc Res
2021
33569824
Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy.
J Magn Reson Imaging
2021
33484825
Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury.
Free Radic Biol Med
2021
33588049
Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling.
Free Radic Biol Med
2021
33914182
The Redox Modulating Sonlicromanol Active Metabolite KH176m and the Antioxidant MPG Protect Against Short-Duration Cardiac Ischemia-Reperfusion Injury.
Cardiovasc Drugs Ther
2021
34527711
Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces Infarct Size in Presence of Fentanyl, Midazolam and Cangrelor, but Not Propofol.
Front Cardiovasc Med
2021
34205045
Sodium Glucose Co-Transporter 2 Inhibitors Ameliorate Endothelium Barrier Dysfunction Induced by Cyclic Stretch through Inhibition of Reactive Oxygen Species.
Int J Mol Sci
2021
33048256
Novel Anti-inflammatory Effects of Canagliflozin Involving Hexokinase II in Lipopolysaccharide-Stimulated Human Coronary Artery Endothelial Cells.
Cardiovasc Drugs Ther
2021
32194159
SGLT2 inhibitors reduce infarct size in reperfused ischemic heart and improve cardiac function during ischemic episodes in preclinical models.
Biochim Biophys Acta Mol Basis Dis
2020
31985828
Effect of hyperglycaemia and diabetes on acute myocardial ischaemia-reperfusion injury and cardioprotection by ischaemic conditioning protocols.
Br J Pharmacol
2020
33344518
Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts.
Front Cardiovasc Med
2020
33362773
NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart.
Front Immunol
2020
32950054
Does acute treatment of dapagliflozin reduce cardiac infarct size through direct cardiac effects or reductions in blood glucose levels?
Cardiovasc Diabetol
2020
32384583
Cardiac metabolism as a driver and therapeutic target of myocardial infarction.
J Cell Mol Med
2020
32562699
Targeting metabolic pathways to treat cardiovascular diseases.
Biochim Biophys Acta Mol Basis Dis
2020
30649212
Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts.
Cardiovasc Res
2019
31724838
Empagliflozin and Dapagliflozin Reduce ROS Generation and Restore NO Bioavailability in Tumor Necrosis Factor α-Stimulated Human Coronary Arterial Endothelial Cells.
Cell Physiol Biochem
2019
31697425
Volume incompliance and transfusion are essential for transfusion-associated circulatory overload: a novel animal model.
Transfusion
2019
31356546
NLRP3 Inflammasome in Cardioprotective Signaling.
J Cardiovasc Pharmacol
2019
31425237
Ketamine-(Dex)Medetomidine, Hyperglycemia, Glycocalyx, and Vascular Permeability.
Anesth Analg
2019
30941055
Editorial: Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches.
Front Physiol
2019
30576455
Innate immunity as a target for acute cardioprotection.
Cardiovasc Res
2019
30461025
Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion.
Transfusion
2019
29159800
Effects of combined helium pre/post-conditioning on the brain and heart in a rat resuscitation model.
Acta Anaesthesiol Scand
2018
30519189
Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients.
Front Physiol
2018
29555979
Helium alters the cytoskeleton and decreases permeability in endothelial cells cultured in vitro through a pathway involving Caveolin-1.
Sci Rep
2018
29635338
Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B.
Cardiovasc Res
2018
29514047
Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome.
Biochim Biophys Acta Mol Basis Dis
2018
29600031
Remote ischaemic preconditioning of the lung: from bench to bedside-are we there yet?
J Thorac Dis
2018
29283977
Divergent Effects of Hypertonic Fluid Resuscitation on Renal Pathophysiological and Structural Parameters in Rat Model of Lower Body Ischemia/Reperfusion-Induced Sterile Inflammation.
Shock
2018
29197997
Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na<sup>+</sup>/H<sup>+</sup> exchanger, lowering of cytosolic Na<sup>+</sup> and vasodilation.
Diabetologia
2018
27752710
Empagliflozin decreases myocardial cytoplasmic Na<sup>+</sup> through inhibition of the cardiac Na<sup>+</sup>/H<sup>+</sup> exchanger in rats and rabbits.
Diabetologia
2017
28356068
A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients.
BMC Anesthesiol
2017
28986541
Cyclophilin D ablation is associated with increased end-ischemic mitochondrial hexokinase activity.
Sci Rep
2017
28626071
NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity.
J Exp Med
2017
28641785
Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart.
Metabolism
2017
1 - 50 of 116
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Co-authored papers
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6
Sander M Houten
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Nicole P Juffermans
Erasmus University Medical Center
Co-authored papers
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University of Amsterdam
Co-authored papers
3
Hossein Ardehali
Co-authored papers
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Marcus J Schultz
Amsterdam University Medical Centers
Co-authored papers
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Jennifer A Muszynski
0Nationwide Children's Hospital
Co-authored papers
1
Alexander P J Vlaar
University of Amsterdam
Co-authored papers
1
Marieke J H Coenen
Co-authored papers
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Mathijs R Wirtz
Amsterdam University Medical Centres
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Philip C Spinella
Pittsburgh University
Co-authored papers
1
Peter Pickkers
Radboud University Medical Centre
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1
Anthonius de Boer
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James M Downey
Co-authored papers
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Gerhard Liebisch
Co-authored papers
1
Fabio Di Lisa
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1
Jordy Jurgens
Academic Medical Center
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Bernard J Gersh
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