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TKG
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Author Details
Full Name
Kim E Nichols
Affiliation
St. Jude Children's Research Hospital
ORCID
Career Start Year
1986
Papers
241
H Index
63
Expertise
CM4AI Collaborator
Antoine Forget (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37823831
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Cancer Discov
2024
37548271
Constitutional balanced translocations involving SMARCB1: A rare cause of rhabdoid tumor predisposition syndrome.
Genes Chromosomes Cancer
2024
37992218
Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation.
Blood
2024
36913308
Proof-of-principle: targeted childhood leukemia prevention.
Oncotarget
2023
37487610
The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS).
Ann Rheum Dis
2023
37522715
ETV6 represses inflammatory response genes and regulates HSPC function during stress hematopoiesis in mice.
Blood Adv
2023
37797633
Cancer germline predisposing variants and late mortality from subsequent malignant neoplasms among long-term childhood cancer survivors: a report from the St Jude Lifetime Cohort and the Childhood Cancer Survivor Study.
Lancet Oncol
2023
37620322
Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice.
Nat Commun
2023
37944075
Parent Quality of Life After Disclosure of Pediatric Oncology Germline Sequencing Results.
JCO Precis Oncol
2023
37971762
Hyperactive TLR signaling: putting the "H" in HÂ syndrome.
Blood
2023
37869077
Germline landscape of <i>RPA1, RPA2 and RPA3</i> variants in pediatric malignancies: identification of <i>RPA1</i> as a novel cancer predisposition candidate gene.
Front Oncol
2023
35652336
Phase II study of alisertib as a single agent for treating recurrent or progressive atypical teratoid/rhabdoid tumor.
Neuro Oncol
2023
36993649
The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study.
Res Sq
2023
37191489
MRI Features for Identifying <i>MYCN</i>-amplified <i>RB1</i> Wild-type Retinoblastoma.
Radiology
2023
37023453
How I communicate with patients and families about germ line genetic information.
Blood
2023
37279817
Adolescent and Young Adult Understanding of Their Childhood Cancer Predisposition Diagnosis: A Qualitative Study.
J Pediatr
2023
37377903
Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome.
Cancer Res Commun
2023
37073685
Germline genomic findings in children and young adults with melanocytic tumors.
Pediatr Blood Cancer
2023
37166930
Deciphering genetic uncertainty in familial HLH.
Blood
2023
36969228
Insights into the cellular pathophysiology of familial hemophagocytic lymphohistiocytosis.
Front Immunol
2023
37228616
Cellular and transcriptional impacts of Janus kinase and/or IFN-gamma inhibition in a mouse model of primary hemophagocytic lymphohistiocytosis.
Front Immunol
2023
36813544
Germline pathogenic <i>SMARCA4</i> variants in neuroblastoma.
J Med Genet
2023
36693186
Pathogenic Variants in Adult-Onset Cancer Predisposition Genes in Pediatric Cancer: Prevalence and Impact on Tumor Molecular Features and Clinical Management.
Clin Cancer Res
2023
34675114
Clinical and Functional Significance of TP53 Exon 4-Intron 4 Splice Junction Variants.
Mol Cancer Res
2022
35479646
Towards the prevention of childhood leukemia.
Oncoscience
2022
35471132
Managing Pandora's Box: Familial Expectations around the Return of (Future) Germline Results.
AJOB Empir Bioeth
2022
37090027
Case Series: Neurobehavioral Profile of Adolescents with PTEN Hamartoma Tumor Syndrome.
J Pediatr Neuropsychol
2022
36001348
Collaboration to Promote Research and Improve Clinical Care in the Evolving Field of Childhood Cancer Predisposition.
Cancer Prev Res (Phila)
2022
36206094
Recent advances in the treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome.
Curr Opin Allergy Clin Immunol
2022
36265116
Parental Preferences Surrounding Timing and Content of Consent Conversations for Clinical Germline Genetic Testing Following a Child's New Cancer Diagnosis.
JCO Precis Oncol
2022
35131871
Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice.
Cancer Res
2022
34996063
Development of BRAFV600E-positive acute myeloid leukemia in a patient on long-term dabrafenib for multisystem LCH.
Blood Adv
2022
34992263
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.
Nat Med
2022
34710216
CPX-351 induces remission in newly diagnosed pediatric secondary myeloid malignancies.
Blood Adv
2022
32693409
Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia.
Blood
2021
33624449
Creating a cancer genomics curriculum for pediatric hematology-oncology fellows: A national needs assessment.
Cancer Med
2021
33737307
Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials.
Clin Cancer Res
2021
33664745
Use of the JAK Inhibitor Ruxolitinib in the Treatment of Hemophagocytic Lymphohistiocytosis.
Front Immunol
2021
33579957
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms.
Nat Commun
2021
33856445
RHOG: Rac1-ing up another HLH gene.
Blood
2021
33914076
HLH or sepsis: the truth is in the T cells.
Blood
2021
34868048
Digenic Inheritance: Evidence and Gaps in Hemophagocytic Lymphohistiocytosis.
Front Immunol
2021
34617981
Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes.
JAMA Oncol
2021
34473566
Identifying Childhood Cancer Survivors at Increased Genetic Risk for Second Malignant Neoplasms: Use of a Novel Screening Tool.
J Clin Oncol
2021
34709361
Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis.
JAMA Oncol
2021
34301788
Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing.
Cancer Discov
2021
34127338
Knowledge Is Power: Benefits, Risks, Hopes, and Decision-Making Reported by Parents Consenting to Next-Generation Sequencing for Children and Adolescents with Cancer.
Semin Oncol Nurs
2021
33981229
Ruxolitinib, a JAK1/2 Inhibitor, Ameliorates Cytokine Storm in Experimental Models of Hyperinflammation Syndrome.
Front Pharmacol
2021
34263927
Hemophagocytic lymphohistiocytosis-like toxicity (carHLH) after CD19-specific CAR T-cell therapy.
Br J Haematol
2021
34166225
Germline RUNX1 variation and predisposition to childhood acute lymphoblastic leukemia.
J Clin Invest
2021
1 - 50 of 241
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Co-authored papers
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Co-authored papers
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John Easton
St Jude Children's Research Hospital
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Ninad Oak
St. Jude Children's Research Hospital
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Michael Rusch
St Jude Children's Research Hospital
Co-authored papers
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Zhaoming Wang
St Jude Children's Research Hospital
Co-authored papers
10
Leslie L Robison
St. Jude Children's Research Hospital
Co-authored papers
10
Kayla V Hamilton
St Jude Children's Research Hospital
Co-authored papers
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Judy E Garber
Dana-Farber Cancer Institute
Co-authored papers
9
Alberto S Pappo
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David W Ellison
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Michael F Walsh
Memorial Sloan Kettering Cancer Center
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Peng Guan
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