Author details

Full Name

Evripidis Gavathiotis

Affiliation

Albert Einstein College of Medicine

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36496299	Mitochondrial dynamics proteins as emerging drug targets.	Trends Pharmacol Sci	2023
38051103	Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors.	Cancer Res Commun	2023
37821702	Apoptotic stress causes mtDNA release during senescence and drives the SASP.	Nature	2023
37100955	Apoptotic cell death in disease-Current understanding of the NCCD 2023.	Cell Death Differ	2023
36383673	Chaperone-mediated autophagy regulates adipocyte differentiation.	Sci Adv	2022
35864098	Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.	Nat Commun	2022
33442062	Chaperone-mediated autophagy sustains haematopoietic stem-cell function.	Nature	2021
33602934	Eltrombopag directly inhibits BAX and prevents cell death.	Nat Commun	2021
33891876	Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.	Cell	2021
34110247	Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis.	Autophagy	2021
32421206	In Response to Regarding: Apoptosis Signaling Molecules as Treatment Targets in Head and Neck Squamous Carcinoma.	Laryngoscope	2020
31894587	Apoptosis signaling molecules as treatment targets in head and neck squamous cell carcinoma.	Laryngoscope	2020
31048321	Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.	Cancer Discov	2019
29677443	ICBS 2017 in Shanghai-Illuminating Life with Chemical Innovation.	ACS Chem Biol	2018
29674596	MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.	Science	2018
29362479	Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.	Cell Death Differ	2018
29492188	Pulling the BAX trigger for tumor cell death.	Oncotarget	2018
29461827	Current Insights of BRAF Inhibitors in Cancer.	J Med Chem	2018
28735187	Progress in targeting the BCL-2 family of proteins.	Curr Opin Chem Biol	2017
28465352	Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.	J Biol Chem	2017
29083320	Pharmacological inhibition of the transcription factor PU.1 in leukemia.	J Clin Invest	2017
28984291	New perspectives for targeting RAF kinase in human cancer.	Nat Rev Cancer	2017
29017059	Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.	Cancer Cell	2017
28801102	Editorial overview: Chemical genetics and epigenetics.	Curr Opin Chem Biol	2017
26799652	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).	Autophagy	2016
26565029	Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site.	J Biol Chem	2016
27768876	An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.	Mol Cell	2016
27702998	Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation: DRUGGABILITY OF THE SMALL GTPase Rab27a.	J Biol Chem	2016
27626173	Self-regulation of BAX-induced cell death.	Oncotarget	2016
27775718	Correcting mitochondrial fusion by manipulating mitofusin conformations.	Nature	2016
27622340	An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.	Cancer Cell	2016
27425408	An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.	Mol Cell	2016
27523909	An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.	Cancer Cell	2016
27315536	Chemical genetics: Unraveling cell death mysteries.	Nat Chem Biol	2016
25437618	Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.	Eur J Med Chem	2015
26344567	An interconnected hierarchical model of cell death regulation by the BCL-2 family.	Nat Cell Biol	2015
25684204	Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism.	Mol Cell	2015
24358963	Distinct BimBH3 (BimSAHB) stapled peptides for structural and cellular studies.	ACS Chem Biol	2014
25049413	Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.	Proc Natl Acad Sci U S A	2014
25076060	Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim.	Mar Drugs	2014
23584676	Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives.	Nat Chem Biol	2013
23890007	Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3.	Chem Biol	2013
22622039	A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.	J Clin Invest	2012
22999885	A competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survival.	Chem Biol	2012
22493254	Bax regulates primary necrosis through mitochondrial dynamics.	Proc Natl Acad Sci U S A	2012
22634637	Direct and selective small-molecule activation of proapoptotic BAX.	Nat Chem Biol	2012
21325897	Tracking BAX once its trigger is pulled.	Cell Cycle	2011
21978892	BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore.	Trends Biochem Sci	2011
20660316	Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic.	Proc Natl Acad Sci U S A	2010
21070973	BH3-triggered structural reorganization drives the activation of proapoptotic BAX.	Mol Cell	2010

1 - 50 of 59

Evangelos Pazarentzos

University of California san francisco

Career Start Year 2011

Number of shared co-authors 1

Nehme El-Hachem

Centre Hospitalier Universitaire Sainte-Justine Research Centre

Career Start Year 2011

Number of shared co-authors 0

Daniel D'Andrea

Nottingham Trent University

Career Start Year 2010

Number of shared co-authors 0

Ahmed Aman

Ontario Institute for Cancer Research, University Avenue

Career Start Year 2007

Number of shared co-authors 1

Isabelle Martins

Universite de Paris, Sorbonne Universite, Inserm U8, Institut Universitaire de France

Career Start Year 2007

Number of shared co-authors 2

James R Whittle

Walter and Eliza Hall Institute of Medical Research

Career Start Year 2006

Number of shared co-authors 0

Kris C Wood

Duke University

Career Start Year 2005

Number of shared co-authors 4

Lisa M Miller Jenkins

National Cancer Institute, National Institutes of Health

Career Start Year 2005

Number of shared co-authors 1

Jianwei Che

Dana-Farber Cancer Institute

Career Start Year 2005

Number of shared co-authors 3

Malia B Potts

St. Jude Children's Research Hospital

Career Start Year 2004

Number of shared co-authors 1

Anang A Shelat

St. Jude Children's Research Hospital

Career Start Year 2003

Number of shared co-authors 1

Almer M van der Sloot

Institute for Research in Immunology and Cancer, Universite de Montreal

Career Start Year 2003

Number of shared co-authors 1

William H Bisson

Knight Cancer Institute, Oregon Health & Science University

Career Start Year 2001

Number of shared co-authors 1

Craig J Thomas

Center for Cancer Research, National Cancer Institute

Career Start Year 2001

Number of shared co-authors 6

Nancy Su

Career Start Year 2000

Number of shared co-authors 0

Rima Al-Awar

Ontario Institute for Cancer Research, University Avenue

Career Start Year 1999

Number of shared co-authors 1

Chandra C Ghosh

The Wistar Institute

Career Start Year 1999

Number of shared co-authors 1

Rose Hurren

Princess Margaret Cancer Centre

Career Start Year 1999

Number of shared co-authors 0

Kenneth D Westover

University of Texas Southwestern Medical Center

Career Start Year 1998

Number of shared co-authors 3

Michael C Bassik

Stanford University Medical Center

Career Start Year 1997

Number of shared co-authors 5

Ranjini K Sundaram

Yale University

Career Start Year 1996

Number of shared co-authors 0

Jack Taunton

University of California san francisco

Career Start Year 1996

Number of shared co-authors 3

Krister Wennerberg

University of Copenhagen

Career Start Year 1994

Number of shared co-authors 0

Ute Fischer

Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf

Career Start Year 1992

Number of shared co-authors 2

Marc Ferrer

National Institutes of Health, National Center for Advancing Translational Sciences

Career Start Year 1992

Number of shared co-authors 2

Ricky W Johnstone

The University of Melbourne

Career Start Year 1990

Number of shared co-authors 0

Aaron D Schimmer

Princess Margaret Cancer Centre

Career Start Year 1989

Number of shared co-authors 2

Stuart L Schreiber

Broad Institute

Career Start Year 1985

Number of shared co-authors 7

Stefan Knapp

Institute of Pharmaceutical Chemistry, Goethe University

Career Start Year 1983

Number of shared co-authors 7

David W Andrews

Sunnybrook Research Institute, University of Toronto

Career Start Year 1978

Number of shared co-authors 8

row(s) 1 - 30 of 30

Ana Maria Cuervo

Albert Einstein College of Medicine

Co-authored papers 8

Richard N Kitsis

Co-authored papers 5

Qisheng Xin

Albert Einstein College of Medicine

Co-authored papers 5

Gerald W Dorn

Co-authored papers 4

Susmita Kaushik

Albert Einstein College of Medicine

Co-authored papers 4

Carlos L??pez-Ot??n

Instituto Universitario de Oncologia, Universidad de Oviedo

Co-authored papers 3

Ted M Dawson

Johns Hopkins University School of Medicine

Co-authored papers 3

Antonio Diaz

Albert Einstein College of Medicine, USA Institute for Aging Studies

Co-authored papers 3

Brent R Stockwell

Columbia University

Co-authored papers 3

Inmaculada Tasset

Albert Einstein College of Medicine

Co-authored papers 3

Valina L Dawson

Institute for Cell Engineering, Johns Hopkins University School of Medicine

Co-authored papers 3

Jan Paul Medema

Oncode Institute

Co-authored papers 3

Stuart A Lipton

The Scripps Research Institute, University of California

Co-authored papers 2

Mathieu Bourdenx

University College London, UK Dementia Research Institute

Co-authored papers 2

Michael Karin

Co-authored papers 2

Yves R Juste

Albert Einstein College of Medicine

Co-authored papers 2

Milton H Werner

Inhibikase Therapeutics Inc.

Co-authored papers 2

Jerry E Chipuk

Co-authored papers 2

Rosario Rizzuto

Co-authored papers 2

Peter D Adams

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 2

Meenhard Herlyn

Ellen and Ronald Caplan Cancer Center, The Wistar Institute

Co-authored papers 2

Simone Fulda

Co-authored papers 2

Brian D Dynlacht

New York University Cancer Institute, New York University School of Medicine

Co-authored papers 2

Nicola Di Daniele

University of Rome Tor Vergata

Co-authored papers 2

Laura Santambrogio

Weill Cornell School of Medicine

Co-authored papers 2

Vladimir N Malashkevich

Albert Einstein College of Medicine

Co-authored papers 2

David Sulzer

New York State Psychiatric Institute, Research Foundation for Mental Hygiene

Co-authored papers 2

Ian G Mills

Queen's University Belfast

Co-authored papers 1

Il??ana Antony-Debr??

INSERM, France Villejuif Universite Paris-Saclay

Co-authored papers 1

Hirotaka Watada

Co-authored papers 1

1 - 30

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