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Author Details

Guan Wang
Jilin University
2005
279
43
PMIDPaper TitleJournal TitlePublished Year
38085423Synergistic effect of adavosertib and fimepinostat on acute myeloid leukemia cells by enhancing the induction of DNA damage.Invest New Drugs2024
36482792Three-dimensional analysis of membrane structures associated with tomato spotted wilt virus infection.Plant Cell Environ2023
37799384Small molecules targeting protein-protein interactions for cancer therapy.Acta Pharm Sin B2023
37622525Membrane phospholipid peroxidation promotes loss of dopaminergic neurons in psychological stress-induced Parkinson's disease susceptibility.Aging Cell2023
37484024New hope for tumor immunotherapy: the macrophage-related "do not eat me" signaling pathway.Front Pharmacol2023
37478560Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.Eur J Med Chem2023
37878184Multiple feature fusion transformer for modeling penicillin fermentation process with unequal sampling intervals.Bioprocess Biosyst Eng2023
37604291Acquired resistance to venetoclax plus azacitidine in acute myeloid leukemia: In vitro models and mechanisms.Biochem Pharmacol2023
37119043Targeting epigenetic modifications in Parkinson's disease therapy.Med Res Rev2023
37042119Design, Synthesis, and Antitumor Activity of Potent and Selective EGFR L858R/T790M Inhibitors and Identification of a Combination Therapy to Overcome Acquired Resistance in Models of Non-small-cell Lung Cancer.J Med Chem2023
37407172Therapeutic potential of alkaloid extract from Codonopsis Radix in alleviating hepatic lipid accumulation: insights into mitochondrial energy metabolism and endoplasmic reticulum stress regulation in NAFLD mice.Chin J Nat Med2023
37141532Understanding the effect of temperature downshift on CHO cell growth, antibody titer and product quality by intracellular metabolite profiling and in vivo monitoring of redox state.Biotechnol Prog2023
37370675From Spatial-Temporal Multiscale Modeling to Application: Bridging the Valley of Death in Industrial Biotechnology.Bioengineering (Basel)2023
36921705Silencing EIF3A ameliorates pulmonary arterial hypertension through HDAC1 and PTEN/PI3K/AKT pathway in vitro and in vivo.Exp Cell Res2023
36815052Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy.Acta Pharm Sin B2023
36401884Design, synthesis and biological evaluation of novel diarylacylhydrazones derivatives for the efficient treatment of idiopathic pulmonary fibrosis.Eur J Med Chem2023
36812234Synergistic activity and mechanism of cytarabine and MCL-1 inhibitor AZD5991 against acute myeloid leukemia.Neoplasma2023
36649216Discovery of Novel Indazole Chemotypes as Isoform-Selective JNK3 Inhibitors for the Treatment of Parkinson's Disease.J Med Chem2023
36641861Ras superfamily GTPase activating proteins in cancer: Potential therapeutic targets?Eur J Med Chem2023
36507562SCD1 Sustains Homeostasis of Bulge Niche via Maintaining Hemidesmosomes in Basal Keratinocytes.Adv Sci (Weinh)2023
36796787A systematic evaluation of quenching and extraction procedures for quantitative metabolome profiling of HeLa carcinoma cell under 2D and 3D cell culture conditions.Biotechnol J2023
36894180A complete hydatidiform mole and coexisting viable fetus in a twin pregnancy: a case report with literature review.J Matern Fetal Neonatal Med2023
34002044LncRNA MAGI2-AS3 inhibits tumor progression and angiogenesis by regulating ACY1 via interacting with transcription factor HEY1 in clear cell renal cell carcinoma.Cancer Gene Ther2022
35481944Downregulation of microRNA-124-3p promotes subventricular zone neural stem cell activation by enhancing the function of BDNF downstream pathways after traumatic brain injury in adult rats.CNS Neurosci Ther2022
35840984Emerging strategies to overcome resistance to third-generation EGFR inhibitors.J Hematol Oncol2022
35646548Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy.Acta Pharm Sin B2022
35433470Role of CD155/TIGIT in Digestive Cancers: Promising Cancer Target for Immunotherapy.Front Oncol2022
35464448Identification of the Transgene Integration Site and Host Genome Changes in MRP8-Cre/ires-EGFP Transgenic Mice by Targeted Locus Amplification.Front Immunol2022
35395400Repurposing small-molecule drugs for modulating toxic protein aggregates in neurodegenerative diseases.Drug Discov Today2022
35422021Long non-coding PRNCR1 regulates the proliferation and apoptosis of synoviocytes in osteoarthritis by sponging miR-377-3p.J Orthop Surg Res2022
35785157A Nomogram to Predict Survival in Patients With Locoregional Recurrent Nasopharyngeal Carcinoma Receiving Comprehensive Treatment.Front Oncol2022
35756499Deconvoluting the Complexity of Reactive Oxygen Species (ROS) in Neurodegenerative Diseases.Front Neuroanat2022
35755289Erratum: Author correction to "Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for NTRK fusion cancers" [Acta Pharmaceutica Sinica B 11 (2021) 355-372].Acta Pharm Sin B2022
35662699A Candidate Drug Screen Strategy: The Discovery of Oroxylin A in Scutellariae Radix Against Sepsis <i>via</i> the Correlation Analysis Between Plant Metabolomics and Pharmacodynamics.Front Pharmacol2022
35418683Chemical reprogramming of human somatic cells to pluripotent stem cells.Nature2022
35355406Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.J Cell Mol Med2022
37077808Recent progress in DNA methyltransferase inhibitors as anticancer agents.Front Pharmacol2022
35970840ALOX15-launched PUFA-phospholipids peroxidation increases the susceptibility of ferroptosis in ischemia-induced myocardial damage.Signal Transduct Target Ther2022
36208684Co-targeting of HDAC, PI3K, and Bcl-2 results in metabolic and transcriptional reprogramming and decreased mitochondrial function in acute myeloid leukemia.Biochem Pharmacol2022
36305233CIP2A deficiency promotes depression-like behaviors in mice through inhibition of dendritic arborization.EMBO Rep2022
36285217One-pot synthesis of robust dendritic sulfur quantum dots for two-photon fluorescence imaging and "off-on" detection of hydroxyl radicals and ascorbic acid.Nanoscale Adv2022
36183504Recent advances of β-catenin small molecule inhibitors for cancer therapy: Current development and future perspectives.Eur J Med Chem2022
36078163Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of <i>FLT3</i>-Mutated Acute Myeloid Leukemia.Cells2022
35943677c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.Apoptosis2022
34980358A review on peach gum polysaccharide: Hydrolysis, structure, properties and applications.Carbohydr Polym2022
35311289Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy.J Med Chem2022
34975324CpG-C ODN M362 as an immunoadjuvant for HBV therapeutic vaccine reverses the systemic tolerance against HBV.Int J Biol Sci2022
34942431Transcriptional cyclin-dependent kinases: Potential drug targets in cancer therapy.Eur J Med Chem2022
35172837Nifuroxazide ameliorates pulmonary fibrosis by blocking myofibroblast genesis: a drug repurposing study.Respir Res2022
35026404Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models.Pharmacol Res2022
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Collaborators

Li Zhou
College of Material Science & Engineering, Guilin University of Technology
Co-authored papers 5
Hualiang Jiang
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Co-authored papers 4
Jisuan Tan
Beibu Gulf University, China College of Petroleum and Chemical Engineering
Co-authored papers 4
Jun Wang
Zhongnan Hospital of Wuhan University
Co-authored papers 3
Ronghua Chen
Co-authored papers 2
Xun Bao
Wayne State University School of Medicine, Barbara Ann Karmanos Cancer Institute
Co-authored papers 2
Wing-Kin Sung
Co-authored papers 2
Christoph Reinhard
Lilly Research Laboratories
Co-authored papers 2
Ke Hao
Co-authored papers 2
Jian Cui
Co-authored papers 1
Zeming Huang
College of Chemistry and Materials Science, Anhui Normal University
Co-authored papers 1
Andrea A Baccarelli
Mailman School of Public Health, Columbia University
Co-authored papers 1
Yixing Duan
College of Materials Science and Engineering, Guilin University of Technology
Co-authored papers 1
Ligui Li
New Energy Research Institute, South China University of Technology
Co-authored papers 1
Diane R Gold
Co-authored papers 1
Jun Qin
Co-authored papers 1
Wei Wei
Co-authored papers 1
Chen Wang
College of Life Sciences, Sichuan University
Co-authored papers 1
Liming Liang
Co-authored papers 1
Jian Wang
Institute of Medical Research, Northwestern Polytechnical University
Co-authored papers 1
Sijia Liu
Mayo Clinic, University at Buffalo - North Campus
Co-authored papers 1
Bo Liu
Henan University
Co-authored papers 1
Chunliang Xu
Co-authored papers 1
Wei-Dong Yao
Co-authored papers 1
Yuhua Xue
School of Pharmaceutical Sciences, Xiamen University
Co-authored papers 1
Wah Heng Lee
Co-authored papers 1
Qiaomei Deng
Co-authored papers 1
Brent A Coull
T.H. Chan School of Public Health, Harvard University
Co-authored papers 1
Kai Wang
Pfizer Inc.
Co-authored papers 1
Minjie Luo
Children's Hospital of Philadelphia
Co-authored papers 1
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