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Author Details

John M Kirkwood
UPMC Hillman Cancer Center
1974
588
112
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36029412Patient-reported tolerability of adjuvant ipilimumab (3 or 10 mg/kg) versus high-dose interferon alfa-2b for resected high-risk stage III-IV melanoma in phase III trial E1609.Qual Life Res2023
37857525Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma.J Immunother Cancer2023
37662409Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma.bioRxiv2023
37579248Systemic Therapy for Melanoma: ASCO Guideline Update.J Clin Oncol2023
37494017Melanoma Detection in Alaska Native, American Indian, Asian, Black, Hispanic, and Pacific Islander Patients in a Large Skin Cancer Screening Initiative.JAMA Dermatol2023
37286303Tebentafusp in combination with durvalumab and/or tremelimumab in patients with metastatic cutaneous melanoma: a phase 1 study.J Immunother Cancer2023
37174027Granulomatous and Sarcoid-like Immune-Related Adverse Events following CTLA4 and PD1 Blockade Adjuvant Therapy of Melanoma: A Combined Analysis of ECOG-ACRIN E1609 and SWOG S1404 Phase III Trials and a Literature Review.Cancers (Basel)2023
37435077Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes.Front Immunol2023
37397389Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study.Front Oncol2023
36960318Development and Narrow Validation of Computer Vision Approach to Facilitate Assessment of Change in Pigmented Cutaneous Lesions.JID Innov2023
36477181Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases.Clin Cancer Res2023
36920356Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing.JAMA Dermatol2023
36649675Interferon Alfa-2b Adjuvant Therapy of High-Risk Resected Cutaneous Melanoma: The Eastern Cooperative Oncology Group Trial EST 1684.J Clin Oncol2023
36831449Immunotherapy in Melanoma: Recent Advances and Future Directions.Cancers (Basel)2023
36416836Effectiveness of Adjuvant Pembrolizumab vs High-Dose Interferon or Ipilimumab for Quality-of-Life Outcomes in Patients With Resected Melanoma: A Secondary Analysis of the SWOG S1404 Randomized Clinical Trial.JAMA Oncol2023
35998300Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma.J Clin Oncol2023
35932099Multiple primary melanoma in association with other personal and familial cancers.Cancer Med2023
36166727Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134.J Clin Oncol2023
36166093Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.Clin Cancer Res2023
34482636Neratinib kills B-RAF V600E melanoma via ROS-dependent autophagosome formation and death receptor signaling.Pigment Cell Melanoma Res2022
35587532Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells.Cancer Immunol Res2022
35385051Five-Year Outcomes of a Melanoma Screening Initiative in a Large Health Care System.JAMA Dermatol2022
35709414Prognosis of Patients With Primary Melanoma Stage I and II According to American Joint Committee on Cancer Version 8 Validated in Two Independent Cohorts: Implications for Adjuvant Treatment.J Clin Oncol2022
35583689Clinically Significant Risk Thresholds in the Management of Primary Cutaneous Melanoma: A Survey of Melanoma Experts.Ann Surg Oncol2022
35579997Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy.Clin Cancer Res2022
35659704Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males.J Transl Med2022
35551967A retrospective analysis of the impact of the COVID-19 pandemic on staging at presentation of patients with invasive melanoma.J Am Acad Dermatol2022
36505793Phase I trial of pembrolizumab plus vemurafenib and cobimetinib in patients with metastatic melanoma.Front Oncol2022
36600653Efficacy and safety of lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, in patients with advanced melanoma after progression on immune checkpoint inhibitors and targeted therapies: pooled analysis of consecutive cohorts of the C-144-01 study.J Immunother Cancer2022
36202690Adjuvant pembrolizumab versus placebo in resected high-risk stage II melanoma: Health-related quality of life from the randomized phase 3 KEYNOTE-716 study.Eur J Cancer2022
36356143TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma.Science2022
36265502Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, randomised, phase 3 trial.Lancet Oncol2022
36291758Sentinel Lymph Node Gene Expression Signature Predicts Recurrence-Free Survival in Cutaneous Melanoma.Cancers (Basel)2022
36011010Targeted Long-Read Bisulfite Sequencing Identifies Differences in the <i>TERT</i> Promoter Methylation Profiles between <i>TERT</i> Wild-Type and <i>TERT</i> Mutant Cancer Cells.Cancers (Basel)2022
35879777Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors.J Transl Med2022
35319783Poorer survival outcomes in patients with multiple versus single primary melanoma.Cancer2022
35074904Improved prognosis and evidence of enhanced immunogenicity in tumor and circulation of high-risk melanoma patients with unknown primary.J Immunother Cancer2022
35316223Tim-3 mediates T cell trogocytosis to limit antitumor immunity.J Clin Invest2022
35013003Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma.Cancer Immunol Res2022
34764195Adjuvant Pembrolizumab versus IFNα2b or Ipilimumab in Resected High-Risk Melanoma.Cancer Discov2022
33414132The State of Melanoma: Emergent Challenges and Opportunities.Clin Cancer Res2021
33796406A phase 1 study of NY-ESO-1 vaccine + anti-CTLA4 antibody Ipilimumab (IPI) in patients with unresectable or metastatic melanoma.Oncoimmunology2021
33542131Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients.Science2021
33871399Melanoma-specific expression of the tumor suppressor proteins p16 and PTEN is a favorable prognostic factor in established melanoma brain metastases.Melanoma Res2021
33759768State of Melanoma: An Historic Overview of a Field in Transition.Hematol Oncol Clin North Am2021
33732652Beyond PD-1: The Next Frontier for Immunotherapy in Melanoma.Front Oncol2021
33898322GZ17-6.02 Interacts With [MEK1/2 and B-RAF Inhibitors] to Kill Melanoma Cells.Front Oncol2021
33613873Proteomic profile of melanoma cell-derived small extracellular vesicles in patients' plasma: a potential correlate of melanoma progression.J Extracell Vesicles2021
33753453Neoadjuvant Pembrolizumab and High-Dose IFNα-2b in Resectable Regionally Advanced Melanoma.Clin Cancer Res2021
33557083Early Cortisol and Inflammatory Responses to Parental Cancer and Their Impact on Functional Impairment in Youth.J Clin Med2021
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Collaborators

UPMC Hillman Cancer Center
Co-authored papers 47
University of California Los Angeles (university of california los angeles)
Co-authored papers 30
MD Anderson Cancer Center
Co-authored papers 28
Co-authored papers 25
The University of Texas MD Anderson Cancer Center
Co-authored papers 23
University Hospital Zurich
Co-authored papers 22
Co-authored papers 21
Co-authored papers 19
University of Colorado Anschutz Medical Campus
Co-authored papers 12
University of Virginia
Co-authored papers 12
University of North Carolina
Co-authored papers 12
National Cancer Institute, National Institutes of Health
Co-authored papers 11
Co-authored papers 11
Yale School of Medicine
Co-authored papers 9
Co-authored papers 8
Co-authored papers 8
Co-authored papers 7
The University of Texas MD Anderson Cancer Center
Co-authored papers 7
University of Melbourne
Co-authored papers 7
Co-authored papers 6
Harvard TH Chan School of Public Health
Co-authored papers 6
Co-authored papers 6
University of Pittsburgh Medical Center
Co-authored papers 6
Center for Cellular Engineering, NIH Clinical Center, National Institutes of Health
Co-authored papers 5
St Jude Children's Research Hospital
Co-authored papers 5
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 5
Cutaneous Biology Research Center, Mass. General Hospital, Harvard Medical School
Co-authored papers 5
Northwestern University Feinberg School of Medicine
Co-authored papers 5
Tufts Medical Center
Co-authored papers 5
National and Kapodistrian University of Athens
Co-authored papers 4