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Author Details

Davide Povero
Mayo Clinic
2008
40
23
PMIDPaper TitleJournal TitlePublished Year
36640958Novel oncometabolites and metabolic checkpoints involved in hepatocellular carcinoma development.J Hepatol2023
37598239JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.Sci Rep2023
37973811Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.Sci Rep2023
37061197HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia.J Hepatol2023
37308266Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.J Pharmacol Exp Ther2023
35194091Protein and miRNA profile of circulating extracellular vesicles in patients with primary sclerosing cholangitis.Sci Rep2022
35716152Hepatology Highlights.Hepatology2022
36279149Overcoming Preclinical Safety Obstacles to Discover (<i>S</i>)-<i>N</i>-((1,2,3,5,6,7-Hexahydro-<i>s</i>-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5<i>H</i>-pyrazolo[5,1-<i>b</i>][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.J Med Chem2022
36199236Complement complex 1 subunit q-mediated hepatic stellate cell activation with connective tissue growth factor elevation is a prognostic factor for survival in rat and human chronic liver diseases.Hepatol Commun2022
36121757Hepatology highlights.Hepatology2022
35290694Hepatology Highlights.Hepatology2022
32763266Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.J Hepatol2021
33859335Surface color spectrophotometry in a murine model of steatosis: an accurate technique with potential applicability in liver procurement.Lab Invest2021
34777255Emerging Roles of T Cells in the Pathogenesis of Nonalcoholic Steatohepatitis and Hepatocellular Carcinoma.Front Endocrinol (Lausanne)2021
32923831Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH.Hepatol Commun2020
32818550Hypoxia, hypoxia-inducible gene 2 (HIG2)/HILPDA, and intracellular lipolysis in cancer.Cancer Lett2020
31184999Human induced pluripotent stem cell-derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis.JCI Insight2019
29728708Emricasan, a pan-caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation.J Mol Med (Berl)2018
27639178Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.Hepatology2017
28249038Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis.PLoS One2017
28615649Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis.Sci Rep2017
26912150Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis.Diabetes Metab J2016
25234945Arginase 2 deficiency results in spontaneous steatohepatitis: a novel link between innate immune activation and hepatic de novo lipogenesis.J Hepatol2015
26783552Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cell via microRNAs targeting PPAR-γ.Cell Mol Gastroenterol Hepatol2015
25909884Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation.Cell Death Differ2015
25849214Microparticles release by adipocytes act as "find-me" signals to promote macrophage migration.PLoS One2015
26020857Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis.Nanomedicine (Lond)2015
24681344Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice.J Hepatol2014
25470250Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease.PLoS One2014
25251155Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.PLoS One2014
24795036Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet-induced NASH model.Dig Dis Sci2014
23600493Novel therapeutic targets for nonalcoholic fatty liver disease.Expert Opin Ther Targets2013
24106341Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells.Sci Signal2013
21959987The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells.J Pathol2012
21145826Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells.J Hepatol2011
21563276Dissection of the biphasic nature of hypoxia-induced motogenic action in bone marrow-derived human mesenchymal stem cells.Stem Cells2011
20552556Liver fibrosis: a dynamic and potentially reversible process.Histol Histopathol2010
20818484Oxidative stress parameters in paediatric non-alcoholic fatty liver disease.Int J Mol Med2010
19688698Angiogenesis and liver fibrogenesis.Histol Histopathol2009
18791199Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells.Carcinogenesis2008
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Collaborators

University of California San Diego
Co-authored papers 23
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Co-authored papers 16
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Co-authored papers 4
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Co-authored papers 3
University Clinic for Visceral Surgery and Medicine, Bern University
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Co-authored papers 2
Escola de Administracao de Empresas - FGV, Stanford University, University of California San Diego, University of Sao Paulo, Yale School of Medicine
Co-authored papers 2
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Center for Liver Diseases, Inova Fairfax Hospital
Co-authored papers 2
University of Colorado Denver
Co-authored papers 2
Pinnacle Clinical Research Center
Co-authored papers 2
Virginia Commonwealth University
Co-authored papers 2
John Hunter Children's Hospital
Co-authored papers 1
Mie University
Co-authored papers 1
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Herbert Wertheim School of Public Health, University of California San Diego
Co-authored papers 1
Keck School of Medicine of the University of Southern California
Co-authored papers 1
Mie University Graduate School of Medicine
Co-authored papers 1
Vanderbilt University Medical Center
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Fox Chase Cancer Center
Co-authored papers 1
University of Michigan ann arbor
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Cedars-Sinai Medical Center (CSMC)
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Cliniques Universitaires Saint-Luc (CUSL)
Co-authored papers 1