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Author Details
Full Name
Murat Iskar
Affiliation
Friedrich Miescher Institute for Biomedical Research
ORCID
Career Start Year
2010
Papers
27
H Index
19
Expertise
CM4AI Collaborator
Emma Lundberg (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37386214
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53.
Nat Struct Mol Biol
2023
36266272
Proteogenomics refines the molecular classification of chronic lymphocytic leukemia.
Nat Commun
2022
34879221
Interleukin-10 receptor signaling promotes the maintenance of a PD-1<sup>int</sup> TCF-1<sup>+</sup> CD8<sup>+</sup> TÂ cell population that sustains anti-tumor immunity.
Immunity
2021
31519123
CD8<sup>+</sup> T-cells of CLL-bearing mice acquire a transcriptional program of T-cell activation and exhaustion.
Leuk Lymphoma
2020
32052037
Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response.
Neuro Oncol
2020
31768671
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations.
Acta Neuropathol
2020
32818467
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
2020
30943283
DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas.
Neuro Oncol
2019
31708418
Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration.
Cell Rep
2019
31733513
Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines.
iScience
2019
31118277
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.
Mol Syst Biol
2019
28754746
Tumor-derived exosomes modulate PD-L1 expression in monocytes.
Sci Immunol
2017
26975353
Spatiotemporal variation of mammalian protein complex stoichiometries.
Genome Biol
2016
27872256
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
J Cell Biol
2016
27256313
CART-a chemical annotation retrieval toolkit.
Bioinformatics
2016
25755299
Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).
Mol Cell Proteomics
2015
27135913
Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats.
Cell Syst
2015
27308430
Discovery and validation of the antimetastatic activity of citalopram in colorectal cancer.
Mol Cell Oncol
2015
25038229
Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling.
Cancer Res
2014
25337877
Luminal signalling links cell communication to tissue architecture during organogenesis.
Nature
2014
23129297
DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data.
Bioinformatics
2013
23632384
Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.
Mol Syst Biol
2013
23511206
Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines.
Mol Syst Biol
2013
22153034
Drug discovery in the age of systems biology: the rise of computational approaches for data integration.
Curr Opin Biotechnol
2012
21765950
Network neighbors of drug targets contribute to drug side-effect similarity.
PLoS One
2011
22219721
Prediction of drug combinations by integrating molecular and pharmacological data.
PLoS Comput Biol
2011
20838579
Drug-induced regulation of target expression.
PLoS Comput Biol
2010
1 - 27 of 27
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