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Author Details

Nicholas S Heaton
Duke University School of Medicine
2006
62
27
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36700640Virology under the Microscope-a Call for Rational Discourse.J Virol2023
37808733Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB.bioRxiv2023
37695101Approaches for timeline reductions in pathogenesis studies using genetically modified mice.Microbiol Spectr2023
37578235A low-background, fluorescent assay to evaluate inhibitors of diverse viral proteases.J Virol2023
37774125Segmented, Negative-Sense RNA Viruses of Humans: Genetic Systems and Experimental Uses of Reporter Strains.Annu Rev Virol2023
37675839Influenza virus transcription and progeny production are poorly correlated in single cells.Elife2023
36700653Virology under the Microscope-a Call for Rational Discourse.mSphere2023
36700642Virology under the Microscope-a Call for Rational Discourse.mBio2023
35060315Nonrespiratory sites of influenza-associated disease: mechanisms and experimental systems for continued study.FEBS J2022
35862698A Virion-Based Combination Vaccine Protects against Influenza and SARS-CoV-2 Disease in Mice.J Virol2022
36465279Single-cell genome-wide association reveals that a nonsynonymous variant in <i>ERAP1</i> confers increased susceptibility to influenza virus.Cell Genom2022
36309510Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection.Nat Commun2022
36243002ZBTB7A promotes virus-host homeostasis during human coronavirus 229E infection.Cell Rep2022
35867557<i>In Vivo</i> Profiling of Individual Multiciliated Cells during Acute Influenza A Virus Infection.J Virol2022
35985334Rapid tissue prototyping with micro-organospheres.Stem Cell Reports2022
36282911Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.Sci Signal2022
35030353From high-throughput to therapeutic: host-directed interventions against influenza viruses.Curr Opin Virol2022
35205657The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection.Cancers (Basel)2022
33446553GPER1 is required to protect fetal health from maternal inflammation.Science2021
33658342Engineered influenza virions reveal the contributions of non-hemagglutinin structural proteins to vaccine mediated protection.J Virol2021
34570829Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity.PLoS Pathog2021
34043740TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2.PLoS Pathog2021
34285133Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.Science2021
34257104ETV7 limits antiviral gene expression and control of influenza viruses.Sci Signal2021
32353252Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza.Cell2020
33128895Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.Cell Stem Cell2020
32908976Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 <i>in vitro</i>.bioRxiv2020
32877682Heterogeneity of Antiviral Responses in the Upper Respiratory Tract Mediates Differential Non-lytic Clearance of Influenza Viruses.Cell Rep2020
32843534Development of a Fluorescence-Based, High-Throughput SARS-CoV-2 3CL<sup>pro</sup> Reporter Assay.J Virol2020
31149635Control of antiviral innate immune response by protein geranylgeranylation.Sci Adv2019
31730644Influenza viruses that require 10 genomic segments as antiviral therapeutics.PLoS Pathog2019
31358986DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection.Nat Microbiol2019
31557273Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.PLoS Pathog2019
31404985The Development and Use of Reporter Influenza B Viruses.Viruses2019
30770807Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function.Nat Commun2019
29601497Efforts to Improve the Seasonal Influenza Vaccine.Vaccines (Basel)2018
29899093The Influenza B Virus Hemagglutinin Head Domain Is Less Tolerant to Transposon Mutagenesis than That of the Influenza A Virus.J Virol2018
28588131Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs.mBio2017
29239386Viruses hijack a long non-coding RNA.Nature2017
28813663A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.Cell Rep2017
28727844Revisiting the concept of a cytopathic viral infection.PLoS Pathog2017
28910636Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication.Cell Host Microbe2017
27001854Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity.Proc Natl Acad Sci U S A2016
26789921Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.Immunity2016
26004185Mutational Analysis of Measles Virus Suggests Constraints on Antigenic Variation of the Glycoproteins.Cell Rep2015
26401044Replication-Competent Influenza B Reporter Viruses as Tools for Screening Antivirals and Antibodies.J Virol2015
25135297Long-term survival of influenza virus infected club cells drives immunopathology.J Exp Med2014
23698304In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies.J Virol2013
24277853Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins.Proc Natl Acad Sci U S A2013
24136289Identification and comparative analysis of hepatitis C virus-host cell protein interactions.Mol Biosyst2013
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Collaborators

Duke University School of Medicine
Co-authored papers 11
Icahn School of Medicine at Mount Sinai
Co-authored papers 9
Icahn School of Medicine at Mount Sinai
Co-authored papers 6
NYU Grossman School of Medicine
Co-authored papers 5
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
University of California riverside
Co-authored papers 4
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Co-authored papers 4
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
University of California berkeley
Co-authored papers 3
Columbia University
Co-authored papers 3
University of Iowa
Co-authored papers 3
Fred Hutchinson Cancer Center
Co-authored papers 3
Oregon Health and Science University
Co-authored papers 3
Purdue University
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
University of Utah School of Medicine
Co-authored papers 3
University of Utah School of Medicine
Co-authored papers 3
Louisiana State University
Co-authored papers 3
Co-authored papers 3
University of Michigan ann arbor
Co-authored papers 3
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
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Rockefeller University
Co-authored papers 3
The Children's Hospital of Philadelphia
Co-authored papers 3
University of North Carolina at Chapel Hill.
Co-authored papers 3
Johns Hopkins Bloomberg School of Public Health
Co-authored papers 3
Co-authored papers 3
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3