Author details

Full Name

Shoa L Clarke

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36853849	Does low-density lipoprotein fully explain atherosclerotic risk in familial hypercholesterolemia?		2023
36409989	Genetic evidence for causal relationships between age at natural menopause and the risk of ageing-associated adverse health outcomes.	International Journal of Epidemiology	2023
37961706	CXCL12 regulates coronary artery dominance in diverse populations and links development to disease.	medRxiv	2023
37609230	A Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization.	medRxiv	2023
37414900	A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.	Nat Med	2023
37409455	Contemporary Polygenic Scores of Low-Density Lipoprotein Cholesterol and Coronary Artery Disease Predict Coronary Atherosclerosis in Adolescents and Young Adults.	Circ Genom Precis Med	2023
37399599	A genetically supported drug repurposing pipeline for diabetes treatment using electronic health records.	EBioMedicine	2023
36824841	Impact of Measurement Imprecision on Genetic Association Studies of Cardiac Function.	medRxiv	2023
36576957	The Value of Measuring Lipoprotein(a) in Children.		2023
36996817	Deep learning-enabled analysis of medical images identifies cardiac sphericity as an early marker of cardiomyopathy and related outcomes.	Med	2023
35143253	Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure.	Circ Genom Precis Med	2022
36034645	Broad clinical manifestations of polygenic risk for coronary artery disease in the Women's Health Initiative.	Commun Med (Lond)	2022
35385311	Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.	Sci Adv	2022
35500537	Using Mendelian randomisation to identify opportunities for type 2 diabetes prevention by repurposing medications used for lipid management.	EBioMedicine	2022
35796859	Use of Polygenic Risk Scores for Coronary Heart Disease in Ancestrally Diverse Populations.	Curr Cardiol Rep	2022
35861770	Race and Ethnicity Stratification for Polygenic Risk Score Analyses May Mask Disparities in Hispanics.	Circulation	2022
35915156	Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.	Nat Med	2022
35716666	Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits.	Am J Hum Genet	2022
36550271	Confounders mediate AI prediction of demographics in medical imaging.	NPJ Digit Med	2022
33932569	Editorial commentary: A new era for preventive cardiology.	Trends in Cardiovascular Medicine	2022
34763773	Time to Relax the 40-Year Age Threshold for Pharmacologic Cholesterol Lowering.	J Am Coll Cardiol	2021
33538426	The need for polygenic score reporting standards in evidence-based practice: lipid genetics use case.	Current Opinion in Lipidology	2021
34282949	Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry.	Circ Genom Precis Med	2021
33675770	Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries.	Am J Cardiol	2021
34029116	Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation.	Circ Genom Precis Med	2021
34461749	The Propagation of Racial Disparities in Cardiovascular Genomics Research.	Circ Genom Precis Med	2021
31926863	Cardiorespiratory Fitness, Body Mass Index, and Markers of Insulin Resistance in Apparently Healthy Women and Men.	Am J Med	2020
30022313	Genome-Wide Association Studies of Coronary Artery Disease: Recent Progress and Challenges Ahead.	Current Atherosclerosis Reports	2018
26845687	Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories.	PLoS Computational Biology	2016
23382538	PRISM offers a comprehensive genomic approach to transcription factor function prediction.	Genome Res	2013
24009522	The enhancer landscape during early neocortical development reveals patterns of dense regulation and co-option.	PLoS Genet	2013
22442009	Coding exons function as tissue-specific enhancers of nearby genes.	Genome Res	2012
22876195	Human developmental enhancers conserved between deuterostomes and protostomes.	PLoS Genet	2012
21455939	Control of pelvic girdle development by genes of the Pbx family and Emx2.	Dev Dyn	2011
20436461	GREAT improves functional interpretation of cis-regulatory regions.	Nat Biotechnol	2010