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Author Details

Laurent Fattet
Moores Cancer Center, University of California
2011
28
17
PMIDPaper TitleJournal TitlePublished Year
37532934Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer.Nature2023
37580389Author Correction: Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation.Nat Cell Biol2023
32359191A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor.FEBS J2021
33811140CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly.Proc Natl Acad Sci U S A2021
34045700Netrin-4 regulates stiffness and metastasis.Nat Mater2021
32574556Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex.Dev Cell2020
32049037RREB1 Integrates TGF-β and RAS Signals to Drive EMT.Dev Cell2020
30755531Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling.Proc Natl Acad Sci U S A2019
30804505Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation.Nat Cell Biol2019
31064840Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser-Arg protein substrate.J Biol Chem2019
29335301Mobilization of a splicing factor through a nuclear kinase-kinase complex.Biochem J2018
30185622Molecular interactions connecting the function of the serine-arginine-rich protein SRSF1 to protein phosphatase 1.J Biol Chem2018
30416759Biomaterials to model and measure epithelial cancers.Nat Rev Mater2018
28576472Redirecting SR Protein Nuclear Trafficking through an Allosteric Platform.J Mol Biol2017
27397683Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing.Mol Cell2016
25107915Molecular pathways: linking tumor microenvironment to epithelial-mesenchymal transition in metastasis.Clin Cancer Res2015
26407179The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.PLoS One2015
26443864Nuclear protein kinase CLK1 uses a non-traditional docking mechanism to select physiological substrates.Biochem J2015
26040677TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients.BMC Cancer2015
26083471The forces behind EMT and tumor metastasis.Cell Cycle2015
25893917Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway.Nat Cell Biol2015
25529026Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.Biochem J2015
24910439RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.Cell Rep2014
25242195Combination of a discovery LC-MS/MS analysis and a label-free quantification for the characterization of an epithelial-mesenchymal transition signature.J Proteomics2014
23154409Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition.Development2013
23788427TIF1γ requires sumoylation to exert its repressive activity on TGFβ signaling.J Cell Sci2013
22461896Dynamic regulation of Tgf-B signaling by Tif1γ: a computational approach.PLoS One2012
21597466Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells.EMBO Rep2011
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Collaborators

Brandon E Aubol
University of California San Diego
Co-authored papers 10
Joseph A Adams
University of California San Diego
Co-authored papers 10
Jing Yang
University of California San Diego
Co-authored papers 9
Hae-Yun Jung
College of Life Science, CHA University
Co-authored papers 4
Adam J Engler
University of California
Co-authored papers 4
Albert C Chen
University of California
Co-authored papers 2
Bibiana Franzen Matte
Federal University of Rio Grande do Sul.
Co-authored papers 2
Alexandra C Newton
Co-authored papers 2
Aditya Kumar
Rice University, University of California San Diego
Co-authored papers 2
Robert L Sah
University of California
Co-authored papers 2
Xiang-Dong Fu
Co-authored papers 2
Susan S Taylor
University of California
Co-authored papers 1
Pranjali Beri
University California San Diego La Jolla
Co-authored papers 1
Mike W Matsumoto
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Jacob M Wozniak
The Scripps Research Institute
Co-authored papers 1
Isabelle Ray-Coquard
University Claude Bernard Lyon I
Co-authored papers 1
Matthew G Ondeck
University of California
Co-authored papers 1
David J Gonzalez
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 1
L??on-Charles Tranchevent
University of Luxembourg
Co-authored papers 1
Elena B Pasquale
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Jesse K Placone
University of California San Diego
Co-authored papers 1
Kurt W??thrich
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Christopher M Plunkett
University of California
Co-authored papers 1
Chen-Ting Ma
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Hector Hernandez-Vargas
Co-authored papers 1
Kirsten C Wong
University of California
Co-authored papers 1
Release 1.2