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Author Details

Michael Overduin
University of Alberta
1992
131
39
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36566625Discovery of allosteric SHP2 inhibitors through ensemble-based consensus molecular docking, endpoint and absolute binding free energy calculations.Comput Biol Med2023
37396303A conserved epitope in VAR2CSA is targeted by a cross-reactive antibody originating from <i>Plasmodium vivax</i> Duffy binding protein.Front Cell Infect Microbiol2023
36851661SARS-CoV-2 Omicron Subvariants Balance Host Cell Membrane, Receptor, and Antibody Docking via an Overlapping Target Site.Viruses2023
36801589Comprehensive classification of proteins based on structures that engage lipids by COMPOSEL.Biophys Chem2023
36367338How Choice of Model Membrane Affects Protein-Glycosphingolipid Interactions: Insights from Native Mass Spectrometry.Anal Chem2022
35602928Multifaceted membrane binding head of the SARS-CoV-2 spike protein.Curr Res Struct Biol2022
35813872Progressive membrane-binding mechanism of SARS-CoV-2 variant spike proteins.iScience2022
36422153Transmembrane Membrane Readers form a Novel Class of Proteins That Include Peripheral Phosphoinositide Recognition Domains and Viral Spikes.Membranes (Basel)2022
31601145Fgd5 is a Rac1-specific Rho GEF that is selectively inhibited by aurintricarboxylic acid.Small GTPases2021
33600804Multisite interactions of prions with membranes and native nanodiscs.Chem Phys Lipids2021
33915422Structural biology of endogenous membrane protein assemblies in native nanodiscs.Curr Opin Struct Biol2021
34946752Effects of Specific Inhibitors for CaMK1D on a Primary Neuron Model for Alzheimer's Disease.Molecules2021
34521767Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer.Proc Natl Acad Sci U S A2021
34351250The phosphoinositide code is read by a plethora of protein domains.Expert Rev Proteomics2021
34069055Regulation of the Phosphoinositide Code by Phosphorylation of Membrane Readers.Cells2021
34204456Structures and Dynamics of Native-State Transmembrane Protein Targets and Bound Lipids.Membranes (Basel)2021
34368138Phosphoinositide Recognition Sites Are Blocked by Metabolite Attachment.Front Cell Dev Biol2021
32841614Structure and function of proteins in membranes and nanodiscs.Biochim Biophys Acta Biomembr2021
32454010The effect of hydrophobic alkyl sidechains on size and solution behaviors of nanodiscs formed by alternating styrene maleamic copolymer.Biochim Biophys Acta Biomembr2020
32081916Binding of the periplakin linker requires vimentin acidic residues D176 and E187.Commun Biol2020
31678368Expression and detergent free purification and reconstitution of the plant plasma membrane Na<sup>+</sup>/H<sup>+</sup> antiporter SOS1 overexpressed in Pichia pastoris.Biochim Biophys Acta Biomembr2020
33315009Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation.Elife2020
32606038The ER chaperone calnexin controls mitochondrial positioning and respiration.Sci Signal2020
32712070Molecular mechanism of intermediate filament recognition by plakin proteins.Biochim Biophys Acta Mol Cell Res2020
32780785Homogeneous nanodiscs of native membranes formed by stilbene-maleic-acid copolymers.Nanoscale2020
32358064Native nanodiscs formed by styrene maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids.J Biol Chem2020
32145282Characterization of multimeric daptomycin bound to lipid nanodiscs formed by calcium-tolerant styrene-maleic acid copolymer.Biochim Biophys Acta Biomembr2020
32433887Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity <i>in Vivo</i> Mouse Model.J Med Chem2020
32535836Backbone resonance assignments of the catalytic and regulatory domains of Ca<sup>2+</sup>/calmodulin-dependent protein kinase 1D.Biomol NMR Assign2020
30508515Memtein: The fundamental unit of membrane-protein structure and function.Chem Phys Lipids2019
31242812Structures and Interactions of Transmembrane Targets in Native Nanodiscs.SLAS Discov2019
31219457JoVE Methods Collection Highlights: Protein-Protein Interactions.J Vis Exp2019
30308128Structure and function of the Fgd family of divergent FYVE domain proteins <sup>1</sup>.Biochem Cell Biol2019
29056560Membrane biology visualized in nanometer-sized discs formed by styrene maleic acid polymers.Biochim Biophys Acta Biomembr2018
29891536Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.Blood2018
30201701YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium.Infect Immun2018
30451240Measuring Interactions of Globular and Filamentous Proteins by Nuclear Magnetic Resonance Spectroscopy (NMR) and Microscale Thermophoresis (MST).J Vis Exp2018
30451239Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering.J Vis Exp2018
29520003Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting.Nat Commun2018
28279219Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.Mol Neurodegener2017
26935805Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin.Nat Commun2016
26590577Sequence-specific 1H, 13C and 15N backbone resonance assignments of the plakin repeat domain of human envoplakin.Biomol NMR Assign2016
27593112Small-Molecule Protein-Protein Interaction Inhibitor of Oncogenic Rho Signaling.Cell Chem Biol2016
27304967Structural Mechanisms and Drug Discovery Prospects of Rho GTPases.Cells2016
27553233NMR of Membrane Proteins: Beyond Crystals.Adv Exp Med Biol2016
27492395Secondary structure and (1)H, (13)C and (15)N resonance assignments of Skint-1: a selecting ligand for a murine γδ T cell subset implicated in tumour suppression.Biomol NMR Assign2016
27254461A method for detergent-free isolation of membrane proteins in their local lipid environment.Nat Protoc2016
27578500The CD63-Syntenin-1 Complex Controls Post-Endocytic Trafficking of Oncogenic Human Papillomaviruses.Sci Rep2016
26917727Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection.J Biol Chem2016
25579996Structural basis of dynamic membrane recognition by trans-Golgi network specific FAPP proteins.J Mol Biol2015
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Collaborators

David Cowburn
Albert Einstein College of Medicine
Co-authored papers 4
Christopher G Burd
Yale School of Medicine
Co-authored papers 3
Ruben Abagyan
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 3
Scott D Emr
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 3
Ulrich L G??nther
Institute of Chemistry and Metabolomics, University of Lubeck
Co-authored papers 2
Stefan Knapp
Institute of Pharmaceutical Chemistry, Goethe University
Co-authored papers 2
Glenn D Prestwich
Co-authored papers 2
Kai Simons
Germany Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 2
Patrick Yau
University of Adelaide Department of Surgery, Royal Adelaide Hospital
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Matthew P Crump
University of Bristol
Co-authored papers 1
Alexander P Golovanov
The University of Manchester
Co-authored papers 1
David A Case
Rutgers University
Co-authored papers 1
Oliver F Lange
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
Gordon C K Roberts
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 1
Josep Rizo
University of Texas Southwestern Medical Center
Co-authored papers 1
Mike P Williamson
The University of Sheffield
Co-authored papers 1
Lu-Yun Lian
Institute of Systems, The University of Liverpool
Co-authored papers 1
Igor L Barsukov
Institute of Integrative Biology, University of Liverpool
Co-authored papers 1
David E Shaw
Columbia University
Co-authored papers 1
Ad Bax
National Institutes of Health
Co-authored papers 1
Patrick C A van der Wel
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
David Middleton
Co-authored papers 1
Ioannis Vakonakis
University of Oxford
Co-authored papers 1
Thomas A Frenkiel
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
Ernest D Laue
University of Cambridge
Co-authored papers 1
Gordon S Rule
Carnegie Mellon University
Co-authored papers 1
Stephen Matthews
Imperial College London
Co-authored papers 1
Robert C Murphy
Co-authored papers 1
Chien Ho
Carnegie Mellon University
Co-authored papers 1
Release 1.2