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Author Details
Full Name
Ian A Sigal
Affiliation
University of Pittsburgh
ORCID
Career Start Year
2004
Papers
114
H Index
39
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36935071
Who bears the load? IOP-induced collagen fiber recruitment over the corneoscleral shell.
Exp Eye Res
2023
37898229
2D or not 2D? Mapping the in-depth inclination of the collagen fibers of the corneoscleral shell.
Exp Eye Res
2023
37193214
Instant polarized light microscopy pi (IPOLÏ¿) for quantitative imaging of collagen architecture and dynamics in ocular tissues.
Opt Lasers Eng
2023
36993476
Predatory Bacteria can Reduce <i>Pseudomonas aeruginosa</i> Induced Corneal Perforation and Proliferation in a Rabbit Keratitis Model.
bioRxiv
2023
37215028
Direct measurements of collagen fiber recruitment in the posterior pole of the eye.
bioRxiv
2023
37146902
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model.
Ocul Surf
2023
37207867
A direct fiber approach to model sclera collagen architecture and biomechanics.
Exp Eye Res
2023
37365268
Posterior scleral birefringence measured by triple-input polarization-sensitive imaging as a biomarker of myopia progression.
Nat Biomed Eng
2023
36965593
Individual astrocyte morphology in the collagenous lamina cribrosa revealed by multicolor DiOlistic labeling.
Exp Eye Res
2023
36778384
Instant polarized light microscopy pi (IPOLÏ¿) for quantitative imaging of collagen architecture and dynamics in ocular tissues.
bioRxiv
2023
36778255
In vivo Modulation of Intraocular and Intracranial Pressures Causes Nonlinear and Non-monotonic Deformations of the Lamina Cribrosa and Scleral Canal.
bioRxiv
2023
35196556
A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography.
Acta Biomater
2022
35568202
Eye-specific 3D modeling of factors influencing oxygen concentration in the lamina cribrosa.
Exp Eye Res
2022
35862065
Evidence of an Annexin A4 mediated plasma membrane repair response to biomechanical strain associated with glaucoma pathogenesis.
J Cell Physiol
2022
36454578
Comparing Acute IOP-Induced Lamina Cribrosa Deformations Premortem and Postmortem.
Transl Vis Sci Technol
2022
34973204
Lamina cribrosa vessel and collagen beam networks are distinct.
Exp Eye Res
2022
35266993
A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network.
J Biomech Eng
2022
35114213
Real-time imaging of optic nerve head collagen microstructure and biomechanics using instant polarized light microscopy.
Exp Eye Res
2022
33103363
Instant polarized light microscopy for imaging collagen microarchitecture and dynamics.
J Biophotonics
2021
34736887
Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo.
Exp Eye Res
2021
31412277
Scleral structure and biomechanics.
Prog Retin Eye Res
2020
33165501
So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult.
Invest Ophthalmol Vis Sci
2020
32805265
Role of radially aligned scleral collagen fibers in optic nerve head biomechanics.
Exp Eye Res
2020
33001158
Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases.
Invest Ophthalmol Vis Sci
2020
32585309
Collagen fiber interweaving is central to sclera stiffness.
Acta Biomater
2020
32211567
Connective Tissue Remodeling in Myopia and its Potential Role in Increasing Risk of Glaucoma.
Curr Opin Biomed Eng
2020
29332130
Cerebrospinal Fluid Pressure: Revisiting Factors Influencing Optic Nerve Head Biomechanics.
Invest Ophthalmol Vis Sci
2018
30025116
Spatial Patterns and Age-Related Changes of the Collagen Crimp in the Human Cornea and Sclera.
Invest Ophthalmol Vis Sci
2018
30142444
Peripapillary sclera architecture revisited: A tangential fiber model and its biomechanical implications.
Acta Biomater
2018
29847664
Seeing the Hidden Lamina: Effects of Exsanguination on the Optic Nerve Head.
Invest Ophthalmol Vis Sci
2018
30372734
Thin Lamina Cribrosa Beams Have Different Collagen Microstructure Than Thick Beams.
Invest Ophthalmol Vis Sci
2018
30304458
Radial and Circumferential Collagen Fibers Are a Feature of the Peripapillary Sclera of Human, Monkey, Pig, Cow, Goat, and Sheep.
Invest Ophthalmol Vis Sci
2018
30277032
Structured polarized light microscopy for collagen fiber structure and orientation quantification in thick ocular tissues.
J Biomed Opt
2018
29361354
Gaze-Evoked Deformations in Optic Nerve Head Drusen: Repetitive Shearing as a Potential Factor in the Visual and Vascular Complications.
Ophthalmology
2018
29633576
Polarized light microscopy for 3-dimensional mapping of collagen fiber architecture in ocular tissues.
J Biophotonics
2018
29574185
Collagen fiber recruitment: A microstructural basis for the nonlinear response of the posterior pole of the eye to increases in intraocular pressure.
Acta Biomater
2018
29660327
Crimp around the globe; patterns of collagen crimp across the corneoscleral shell.
Exp Eye Res
2018
29740064
Tortuous Pore Path Through the Glaucomatous Lamina Cribrosa.
Sci Rep
2018
28687851
Microstructural Crimp of the Lamina Cribrosa and Peripapillary Sclera Collagen Fibers.
Invest Ophthalmol Vis Sci
2017
28324116
Thick Prelaminar Tissue Decreases Lamina Cribrosa Visibility.
Invest Ophthalmol Vis Sci
2017
28146238
Collagen Architecture of the Posterior Pole: High-Resolution Wide Field of View Visualization and Analysis Using Polarized Light Microscopy.
Invest Ophthalmol Vis Sci
2017
29618852
Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures.
Proc SPIE Int Soc Opt Eng
2017
29338062
An imaged-based inverse finite element method to determine <i>in-vivo</i> mechanical properties of the human trabecular meshwork.
J Model Ophthalmol
2017
28935889
Formalin Fixation and Cryosectioning Cause Only Minimal Changes in Shape or Size of Ocular Tissues.
Sci Rep
2017
29049736
Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult.
Invest Ophthalmol Vis Sci
2017
29161320
In-vivo effects of intraocular and intracranial pressures on the lamina cribrosa microstructure.
PLoS One
2017
29311754
Correlation between Cerebral Hemodynamic and Perfusion Pressure Changes in Non-Human Primates.
Proc SPIE Int Soc Opt Eng
2017
28855629
Location of the Central Retinal Vessel Trunk in the Laminar and Prelaminar Tissue of Healthy and Glaucomatous Eyes.
Sci Rep
2017
28528864
Effects of collagen microstructure and material properties on the deformation of the neural tissues of the lamina cribrosa.
Acta Biomater
2017
28527594
Whole-globe biomechanics using high-field MRI.
Exp Eye Res
2017
1 - 50 of 114
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Zach Nadler
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Susannah Waxman
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James G Fujimoto
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