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Author Details

Joel E Kleinman
Lieber Institute for Brain Development (LIBD)
1973
372
87
PMIDPaper TitleJournal TitlePublished Year
37915216Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donors' Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.Am J Psychiatry2024
37915216Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donors' Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.Am J Psychiatry2024
36702996Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.Nat Genet2023
37831723Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia.PLoS Genet2023
37986747Comparison of gene expression in living and postmortem human brain.medRxiv2023
37790540Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.medRxiv2023
37786720Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function.bioRxiv2023
37961425Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.medRxiv2023
37404944Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.Front Neurol2023
36824961Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex.bioRxiv2023
36702996Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.Nat Genet2023
37392042Sutton's Law.Am J Psychiatry2023
36945630Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.medRxiv2023
36698068SUFI: an automated approach to spectral unmixing of fluorescent multiplex images captured in mouse and post-mortem human brain tissues.BMC Neurosci2023
37058565Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions.Sci Adv2023
37172721Orthogonal approaches required to measure proteasome composition and activity in mammalian brain tissue.J Biol Chem2023
36608676A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan.Cell Stem Cell2023
37491937Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.Am J Psychiatry2023
37491937Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.Am J Psychiatry2023
37961425Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.medRxiv2023
37790540Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.medRxiv2023
37786720Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function.bioRxiv2023
37986747Comparison of gene expression in living and postmortem human brain.medRxiv2023
37831723Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia.PLoS Genet2023
37392042Sutton's Law.Am J Psychiatry2023
37058565Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions.Sci Adv2023
36945630Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.medRxiv2023
37172721Orthogonal approaches required to measure proteasome composition and activity in mammalian brain tissue.J Biol Chem2023
37404944Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.Front Neurol2023
36698068SUFI: an automated approach to spectral unmixing of fluorescent multiplex images captured in mouse and post-mortem human brain tissues.BMC Neurosci2023
36608676A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan.Cell Stem Cell2023
36824961Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex.bioRxiv2023
35260864Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways.Nat Neurosci2022
35969790Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders.Proc Natl Acad Sci U S A2022
36232351TRIOBP-1 Protein Aggregation Exists in Both Major Depressive Disorder and Schizophrenia, and Can Occur through Two Distinct Regions of the Protein.Int J Mol Sci2022
35868859Variation in TAF1 expression in female carrier induced pluripotent stem cells and human brain ontogeny has implications for adult neostriatum vulnerability in X-linked Dystonia Parkinsonism.eNeuro2022
36332572A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan.Cell Stem Cell2022
35794479Molecular landscapes of human hippocampal immature neurons across lifespan.Nature2022
36319771Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes.Nat Neurosci2022
36319771Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes.Nat Neurosci2022
36845993Differential expression of <i>NPAS4</i> in the dorsolateral prefrontal cortex following opioid overdose.Drug Alcohol Depend Rep2022
35260864Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways.Nat Neurosci2022
35236959Molecular phenotypes associated with antipsychotic drugs in the human caudate nucleus.Mol Psychiatry2022
35236118Genetics and Brain Transcriptomics of Completed Suicide.Am J Psychiatry2022
35794479Molecular landscapes of human hippocampal immature neurons across lifespan.Nature2022
36845993Differential expression of <i>NPAS4</i> in the dorsolateral prefrontal cortex following opioid overdose.Drug Alcohol Depend Rep2022
35969790Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders.Proc Natl Acad Sci U S A2022
35868859Variation in TAF1 expression in female carrier induced pluripotent stem cells and human brain ontogeny has implications for adult neostriatum vulnerability in X-linked Dystonia Parkinsonism.eNeuro2022
36332572A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan.Cell Stem Cell2022
36232351TRIOBP-1 Protein Aggregation Exists in Both Major Depressive Disorder and Schizophrenia, and Can Occur through Two Distinct Regions of the Protein.Int J Mol Sci2022
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