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Author Details

Adam G Sowalsky
National Cancer Institute
2010
52
19
PMIDPaper TitleJournal TitlePublished Year
37816132Defining biology and recurrence risk in prostate cancers treated by neoadjuvant chemohormonal therapy.J Natl Cancer Inst2024
37205576Radiogenomic profiling of prostate tumors prior to external beam radiotherapy converges on a transcriptomic signature of TGF-β activity driving tumor recurrence.medRxiv2023
37790315Prediction of cancer treatment response from histopathology images through imputed transcriptomics.Res Sq2023
37725435Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models.J Clin Invest2023
37220531One toolkit to bring them all, and <i>in silico</i> analyze them.Clin Transl Discov2023
35078018Comment on: Intratumor heterogeneity and clonal evolution revealed in castration-resistant prostate cancer by longitudinal genomic analysis by Jing Li et al.Transl Oncol2022
35695870Assessment of Androgen Receptor Splice Variant-7 as a Biomarker of Clinical Response in Castration-Sensitive Prostate Cancer.Clin Cancer Res2022
36511483Defining cellular population dynamics at single-cell resolution during prostate cancer progression.Elife2022
36181613Progression of prostate cancer reprograms MYC-mediated lipid metabolism via lysine methyltransferase 2A.Discov Oncol2022
36179684Unpacking circulating tumor DNA lends insight into prostate cancer biology and the clonal dynamics of metastasis.Cancer Cell2022
35863822Clinical outcome following checkpoint therapy in renal cell carcinoma is associated with a burst of activated CD8 T cells in blood.J Immunother Cancer2022
35227084Prostate-Specific Membrane Antigen Is a Biomarker for Residual Disease following Neoadjuvant Intense Androgen Deprivation Therapy in Prostate Cancer.J Urol2022
35131873Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer.Cancer Res2022
35082166Modeling Androgen Deprivation Therapy-Induced Prostate Cancer Dormancy and Its Clinical Implications.Mol Cancer Res2022
33023952Sequential Prostate Magnetic Resonance Imaging in Newly Diagnosed High-risk Prostate Cancer Treated with Neoadjuvant Enzalutamide is Predictive of Therapeutic Response.Clin Cancer Res2021
33575208Age and Tumor Differentiation-Associated Gene Expression Based Analysis of Non-Familial Prostate Cancers.Front Oncol2021
33516656AR-V7 biomarker testing for primary prostate cancer: The ongoing challenge of analytical validation and clinical qualification.Cancer Treat Res Commun2021
33899001EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer.Nat Cancer2021
33785256Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy.Eur Urol2021
34911936Androgen receptor and MYC equilibration centralizes on developmental super-enhancer.Nat Commun2021
34568716Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary Tumors.JCO Precis Oncol2021
34415294Comparison of approaches to transcriptomic analysis in multi-sampled tumors.Brief Bioinform2021
34168052A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes.Clin Cancer Res2021
33422353Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer.Eur Urol2021
32944614Battling the two-headed dragon of prostate cancer targeted therapy.Mol Cell Oncol2020
32054861A case report of multiple primary prostate tumors with differential drug sensitivity.Nat Commun2020
29229583Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer.Eur Urol Focus2019
31747605CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.Cell Rep2019
31827286An intra-tumoral niche maintains and differentiates stem-like CD8 T cells.Nature2019
29748182A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening.Clin Cancer Res2018
30103901Molecular correlates of intermediate- and high-risk localized prostate cancer.Urol Oncol2018
30204063Are localized prostate cancer biomarkers useful in the clinical practice?Tumour Biol2018
30012673BMX-Mediated Regulation of Multiple Tyrosine Kinases Contributes to Castration Resistance in Prostate Cancer.Cancer Res2018
29921690Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations.Cancer Res2018
30280090The Role of Immunohistochemical Analysis as a Tool for the Diagnosis, Prognostic Evaluation and Treatment of Prostate Cancer: A Systematic Review of the Literature.Front Oncol2018
30701023A comparison of prostate cancer bone metastases on <sup>18</sup>F-Sodium Fluoride and Prostate Specific Membrane Antigen (<sup>18</sup>F-PSMA) PET/CT: Discordant uptake in the same lesion.Oncotarget2018
29669286Platelets Promote Metastasis via Binding Tumor CD97 Leading to Bidirectional Signaling that Coordinates Transendothelial Migration.Cell Rep2018
28119368Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4.Clin Cancer Res2017
26936914ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer.Clin Cancer Res2016
28133630PRECISION MANAGEMENT OF LOCALIZED PROSTATE CANCER.Expert Rev Precis Med Drug Dev2016
27272561Mutation Profiling Indicates High Grade Prostatic Intraepithelial Neoplasia as Distant Precursors of Adjacent Invasive Prostatic Adenocarcinoma.Prostate2016
27043282SOX9 drives WNT pathway activation in prostate cancer.J Clin Invest2016
25189356Whole transcriptome sequencing reveals extensive unspliced mRNA in metastatic castration-resistant prostate cancer.Mol Cancer Res2015
26473374Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma.Oncotarget2015
25906751Loss of Wave1 gene defines a subtype of lethal prostate cancer.Oncotarget2015
25320358Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors.Clin Cancer Res2015
24449822Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer.Clin Cancer Res2014
23204237Clonal progression of prostate cancers from Gleason grade 3 to grade 4.Cancer Res2013
23426182ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer.J Clin Invest2013
21159665RalA function in dermal fibroblasts is required for the progression of squamous cell carcinoma of the skin.Cancer Res2011
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Collaborators

Beth Israel Deaconess Medical Center and Harvard Medical School
Co-authored papers 19
College of Optical Science and Engineering, Zhejiang University
Co-authored papers 14
National Cancer Institute
Co-authored papers 7
Fred Hutchinson Cancer Center
Co-authored papers 7
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Co-authored papers 7
Center for Personalized Cancer Therapy, University of Massachusetts Boston
Co-authored papers 6
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Co-authored papers 6
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Co-authored papers 6
Weill Medical College of Cornell University
Co-authored papers 5
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 4
Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute
Co-authored papers 4
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
University of Washington
Co-authored papers 3
National Cancer Institute, National Institutes of Health
Co-authored papers 3
Fred Hutchinson Cancer Center
Co-authored papers 3
University of Washington School of Medicine
Co-authored papers 3
Dana-Farber Cancer Institute
Co-authored papers 3
Dana-Farber Cancer Institute
Co-authored papers 3
Center for Personalized Cancer Therapy, University of Massachusetts Boston
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Dana-Farber Cancer Institute
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University of Washington School of Medicine
Co-authored papers 2
The Institute for Cancer Research
Co-authored papers 2
Dana-Farber Cancer Institute
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Emory University School of Medicine
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University of Washington
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Fred Hutchinson Cancer Center, University of Washington
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Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
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The Institute for Cancer Research
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University of British Columbia
Co-authored papers 1