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Author Details

Bradley L Urquhart
Schulich School of Medicine and Dentistry, Western University
2003
68
25
PMIDPaper TitleJournal TitlePublished Year
36657745Metabolomic identification of predictive and early biomarkers of cisplatin-induced acute kidney injury in adult head and neck cancer patients.Br J Clin Pharmacol2023
37151562Investigation of <i>N</i>,<i>N</i>,<i>N</i>-Trimethyl-L-alanyl-L-proline Betaine (TMAP) as a Biomarker of Kidney Function.ACS Omega2023
37126930Metabolomics for the identification of early biomarkers of nephrotoxicity in a mouse model of cisplatin-induced acute kidney injury.Biomed Pharmacother2023
36849161The effect of micro-particle curcumin on chronic kidney disease progression: the MPAC-CKD randomized clinical trial.Nephrol Dial Transplant2023
36181576Cerebrovascular Disease, Cardiovascular Disease, and Chronic Kidney Disease: Interplays and Influences.Curr Neurol Neurosci Rep2022
34820133A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol.Can J Kidney Health Dis2021
33599997Association of Urine Platinum With Acute Kidney Injury in Children Treated With Cisplatin for Cancer.J Clin Pharmacol2021
33668632Uremic Toxins in the Progression of Chronic Kidney Disease and Cardiovascular Disease: Mechanisms and Therapeutic Targets.Toxins (Basel)2021
28398936Endogenous Glucocorticoid Response to Single-Dose Dexamethasone for Croup in Children: A Pharmacodynamic Study.Pediatr Emerg Care2020
33015574Protocol for parallel proteomic and metabolomic analysis of mouse intervertebral disc tissues.JOR Spine2020
32618656Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability: A Randomized Control Trial.Am J Gastroenterol2020
31048706Untargeted metabolomics reveals N, N, N-trimethyl-L-alanyl-L-proline betaine (TMAP) as a novel biomarker of kidney function.Sci Rep2019
30100156Moderate Renal Impairment and Toxic Metabolites Produced by the Intestinal Microbiome: Dietary Implications.J Ren Nutr2019
31393129Crohn's Disease Is Associated with Decreased CYP3A4 and P-Glycoprotein Protein Expression.Mol Pharm2019
31049204The effect of chronic kidney disease on CYP2B expression and activity in male Wistar rats.Pharmacol Res Perspect2019
29519953<i>β</i>-Blocker Dialyzability in Maintenance Hemodialysis Patients: A Randomized Clinical Trial.Clin J Am Soc Nephrol2018
29914158Mediterranean Diet Score: Associations with Metabolic Products of the Intestinal Microbiome, Carotid Plaque Burden, and Renal Function.Nutrients2018
30608180Sapropterin Treatment Prevents Congenital Heart Defects Induced by Pregestational Diabetes Mellitus in Mice.J Am Heart Assoc2018
29702430Metabolic products of the intestinal microbiome and extremes of atherosclerosis.Atherosclerosis2018
28971609Coffee inhibition of CYP3A4 in vitro was not translated to a grapefruit-like pharmacokinetic interaction clinically.Pharmacol Res Perspect2017
27023840Clearance of cardiovascular medications during hemodialysis.Curr Opin Nephrol Hypertens2016
26567910Effect of renal impairment on atherosclerosis: only partially mediated by homocysteine.Nephrol Dial Transplant2016
26372358Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning.Mol Oncol2016
27481881Coffee-Antihypertensive Drug Interaction: A Hemodynamic and Pharmacokinetic Study With Felodipine.Am J Hypertens2016
27197730Metabolomic Response of Skeletal Muscle to Aerobic Exercise Training in Insulin Resistant Type 1 Diabetic Rats.Sci Rep2016
26932318Untargeted plasma and tissue metabolomics in rats with chronic kidney disease given AST-120.Sci Rep2016
26979144Drug Disposition Issues in CKD: Implications for Drug Discovery and Regulatory Approval.Adv Chronic Kidney Dis2016
25219905Effect of erythropoietin on hepatic cytochrome P450 expression and function in an adenine-fed rat model of chronic kidney disease.Br J Pharmacol2015
26282591Downregulation of Hepatic Carbonyl Reductase Type 1 in End-Stage Renal Disease.Drug Metab Lett2015
26187470Folic Acid for Stroke Prevention: Time to Revisit Vitamin Therapy in Patients With Kidney Disease?Am J Kidney Dis2015
25488427Enzymatic and non-enzymatic mechanisms of dimesna metabolism.Amino Acids2015
25453994Effect of CKD and dialysis modality on exposure to drugs cleared by nonrenal mechanisms.Am J Kidney Dis2015
25546506Dried blood spots for therapeutic drug monitoring of tacrolimus and sirolimus in pediatric patients.Pediatr Transplant2015
24212381Protein restoration in low-birth-weight rat offspring derived from maternal low-protein diet leads to elevated hepatic CYP3A and CYP2C11 activity in adulthood.Drug Metab Dispos2014
25208844Decreased nuclear receptor activity and epigenetic modulation associates with down-regulation of hepatic drug-metabolizing enzymes in chronic kidney disease.FASEB J2014
25362071Breast cancer resistance protein substrate and inhibition evaluation: why, when, and how?Drug Metab Dispos2014
24894822CD73-TNAP crosstalk regulates the hypertrophic response and cardiomyocyte calcification due to α1 adrenoceptor activation.Mol Cell Biochem2014
24961255Pharmacokinetic considerations in chronic kidney disease and patients requiring dialysis.Expert Opin Drug Metab Toxicol2014
24533448N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes.Cardiovasc Diabetol2014
24335385Nocturnal home hemodialysis associates with improvement of electrocardiographic features linked to sudden cardiac death.ASAIO J2014
24458728Design it yourself (DIY): in-house instructional design for online pharmacology.Adv Health Sci Educ Theory Pract2014
22870862Silencing IDO in dendritic cells: a novel approach to enhance cancer immunotherapy in a murine breast cancer model.Int J Cancer2013
24192796ECG machine QTc intervals are inaccurate in hemodialysis patients.Nephron Clin Pract2013
23860412Frequent nocturnal hemodialysis associates with improvement of prolonged QTc intervals.Nephron Clin Pract2013
23190184Pharmacokinetic profiles for oral and subcutaneous methotrexate in patients with Crohn's disease.Aliment Pharmacol Ther2013
21505084In vitro and in vivo assessment of renal drug transporters in the disposition of mesna and dimesna.J Clin Pharmacol2012
22484315Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation.Biochem Pharmacol2012
22573661Down-regulation of hepatic CYP3A and CYP2C mediated metabolism in rats with moderate chronic kidney disease.Drug Metab Dispos2012
22167570Disposition of atorvastatin, rosuvastatin, and simvastatin in oatp1b2-/- mice and intraindividual variability in human subjects.J Clin Pharmacol2012
21649730Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2).J Gastroenterol Hepatol2011
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Collaborators

The Lilibeth Caberto Kidney Clinical Research Unit, Western University
Co-authored papers 13
Western University
Co-authored papers 5
Schulich School of Medicine and Dentistry, University of Western Ontario
Co-authored papers 4
Western University
Co-authored papers 3
BC Children's Hospital, University of British Columbia
Co-authored papers 3
Toronto Hospital for Sick Children, University of Toronto
Co-authored papers 3
Schulich School of Medicine and Dentistry, University of Western Ontario
Co-authored papers 2
Western University, Lawson Health Research Institute
Co-authored papers 2
University of Pittsburgh School of Pharmacy
Co-authored papers 2
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 2
University of Nottingham
Co-authored papers 1
Western University
Co-authored papers 1
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 1
The Hospital for Sick Children, University of Toronto
Co-authored papers 1
McGill University
Co-authored papers 1
University of Toronto
Co-authored papers 1
University of British Columbia
Co-authored papers 1
University of Toronto
Co-authored papers 1
New York Institute of Technology College of Osteopathic Medicine
Co-authored papers 1
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 1
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 1
Schulich School of Medicine and Dentistry, The University of Western Ontario
Co-authored papers 1
The Hospital for Sick Children
Co-authored papers 1
British Columbia Children's Hospital, The University of British Columbia
Co-authored papers 1
Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center
Co-authored papers 1
BC Children's Hospital, The University of British Columbia
Co-authored papers 1
Victoria Hospital
Co-authored papers 1
University of California los angeles
Co-authored papers 1
St. Jude Children's Research Hospital
Co-authored papers 1
CytoGnomix Inc.
Co-authored papers 1