Author details

Full Name

Kenneth R McLeish

Affiliation

ORCID

Career Start Year

1977

Papers

145

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37885878	Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation.		2023
36424898	Understanding inhibitory receptor function in neutrophils through the lens of CLEC12A.	Immunological Reviews	2023
35711435	Differential Functional Responses of Neutrophil Subsets in Severe COVID-19 Patients.	Frontiers in Immunology	2022
34638548	Regulation of the Expression, Oligomerisation and Signaling of the Inhibitory Receptor CLEC12A by Cysteine Residues in the Stalk Region.	International Journal of Molecular Sciences	2021
34234773	The Inhibitory Receptor CLEC12A Regulates PI3K-Akt Signaling to Inhibit Neutrophil Activation and Cytokine Release.	Frontiers in Immunology	2021
33669337	Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression.	J Clin Med	2021
33986193	A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients.	JCI insight	2021
32946637	Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions.	Journal of Leukocyte Biology	2021
32561683	Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis.	J Am Soc Nephrol	2020
31990103	Therapeutic targeting of neutrophil exocytosis.	Journal of Leukocyte Biology	2020
30730851	Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.	JCI insight	2019
29790391	Neutrophil exocytosis induces podocyte cytoskeletal reorganization and proteinuria in experimental glomerulonephritis.	Am J Physiol Renal Physiol	2018
30128338	Hepatitis C mixed cryoglobulinemia with undetectable viral load: A case series.	JAAD Case Reports	2018
29720115	Biomarker enhanced risk prediction for development of AKI after cardiac surgery.	BMC Nephrology	2018
28096297	Frontline Science: Tumor necrosis factor-Î± stimulation and priming of human neutrophil granule exocytosis.	Journal of Leukocyte Biology	2017
28638979	Endocytosis is required for exocytosis and priming of respiratory burst activity in human neutrophils.	Inflammation Research	2017
28935578	ABIN1 Determines Severity of Glomerulonephritis via Activation of Intrinsic Glomerular Inflammation.	Am J Pathol	2017
28620081	Re-Examining Neutrophil Participation in GN.	J Am Soc Nephrol	2017
28611952	Multiple Phenotypic Changes Define Neutrophil Priming.	Frontiers in Cellular and Infection Microbiology	2017
27988214	Characterization of glomerular extracellular matrixÂ by proteomic analysis of laser-captured microdissected glomeruli.	Kidney International	2017
27183592	STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus.	Journal of Immunology	2016
24391146	TAT-SNAP-23 treatment inhibits the priming of neutrophil functions contributing to shock and/or sepsis-induced extra-pulmonary acute lung injury.	Innate Immun	2015
25848767	Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators.	PLoS ONE	2015
25824007	Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis.	Proteomics Clin Appl	2015
25907758	Changing the concepts of immune-mediated glomerular diseases through proteomics.	Proteomics Clin Appl	2015
25986013	Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes.	Journal of Leukocyte Biology	2015
24319266	The pore-forming toxin listeriolysin O is degraded by neutrophil metalloproteinase-8 and fails to mediate Listeria monocytogenes intracellular survival in neutrophils.	J Immunol	2014
28509195	Mixed cryoglobulinemia and secondary membranoproliferative glomerulonephritis associated with ehrlichiosis.	CEN Case Reports	2014
23364427	Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats.	Shock	2013
23970121	ABIN1 dysfunction as a genetic basis for lupus nephritis.	J Am Soc Nephrol	2013
23363774	Exocytosis of neutrophil granule subsets and activation of prolyl isomerase 1 are required for respiratory burst priming.	Journal of Innate Immunity	2013
23144171	Antibacterial effect of microvesicles released from human neutrophilic granulocytes.	Blood	2013
23470899	Technical note: proteomic approaches to fundamental questions about neutrophil biology.	Journal of Leukocyte Biology	2013
23336108	Characteristics and outcomes in community-acquired versus hospital-acquired acute kidney injury.	Nephrology (Carlton)	2013
22261956	Writing a first grant proposal.	Nature Immunology	2012
22844115	Olfactomedin 4 inhibits cathepsin C-mediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice.	Journal of Immunology	2012
21642540	Granule exocytosis contributes to priming and activation of the human neutrophil respiratory burst.	Journal of Immunology	2011
21097543	Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation.	Mol Cell Proteomics	2011
19580889	Application of proteomics to neutrophil biology.	Journal of Proteomics	2010
18952697	Anti-proteinase 3 antibodies both stimulate and prime human neutrophils.	Nephrology Dialysis Transplantation	2009
19176760	Counterregulation of clathrin-mediated endocytosis by the actin and microtubular cytoskeleton in human neutrophils.	American Journal of Physiology - Cell Physiology	2009
18390742	Comparison of proteins expressed on secretory vesicle membranes and plasma membranes of human neutrophils.	J Immunol	2008
17202227	The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets.	American Journal of Physiology - Cell Physiology	2007
17609286	Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice.	American Journal of Physiology - Renal Physiology	2007
17277149	Heat shock protein 27 regulates neutrophil chemotaxis and exocytosis through two independent mechanisms.	Journal of Immunology	2007
16823971	A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells.	Journal of Proteome Research	2006
16878704	Proteomic analysis of human neutrophils.	Methods in Molecular Biology	2006
17491655	Proteomic identification and immunolocalization of increased renal calbindin-D28k expression in OVE26 diabetic mice.	Review of Diabetic Studies	2005
15985654	Proteomic analysis of human neutrophil granules.	Mol Cell Proteomics	2005
15905572	Myeloid-related protein-14 is a p38 MAPK substrate in human neutrophils.	Journal of Immunology	2005