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Author Details

Steffen Durinck
Genentech Inc.
2004
48
31
PMIDPaper TitleJournal TitlePublished Year
36419469Population-wide gene disruption in the murine lung epithelium via AAV-mediated delivery of CRISPR-Cas9 components.Mol Ther Methods Clin Dev2022
36419469Population-wide gene disruption in the murine lung epithelium via AAV-mediated delivery of CRISPR-Cas9 components.Mol Ther Methods Clin Dev2022
33443214Single-molecule nanopore sequencing reveals extreme target copy number heterogeneity in arylomycin-resistant mutants.Proc Natl Acad Sci U S A2021
33443214Single-molecule nanopore sequencing reveals extreme target copy number heterogeneity in arylomycin-resistant mutants.Proc Natl Acad Sci U S A2021
34608135Determinants of renal cell carcinoma invasion and metastatic competence.Nat Commun2021
34608135Determinants of renal cell carcinoma invasion and metastatic competence.Nat Commun2021
32839463Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.Nat Commun2020
36618440Embryonic lethality and defective mammary gland development of activator-function impaired conditional knock-in <i>Erbb3</i> <sup><i>V943R</i></sup> mice.Adv Genet (Hoboken)2020
31907489The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins.Nat Genet2020
32009251Atypical presentation and pathogenesis of a macaque lymphocryptoviral-associated B-cell lymphoma in a cynomolgus monkey.Vet Clin Pathol2020
33205067Elevated Serum Amino Acids Induce a Subpopulation of Alpha Cells to Initiate Pancreatic Neuroendocrine Tumor Formation.Cell Rep Med2020
33283855Accurate assembly of the olive baboon (Papio anubis) genome using long-read and Hi-C data.Gigascience2020
32839463Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.Nat Commun2020
36618440Embryonic lethality and defective mammary gland development of activator-function impaired conditional knock-in <i>Erbb3</i> <sup><i>V943R</i></sup> mice.Adv Genet (Hoboken)2020
31907489The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins.Nat Genet2020
32009251Atypical presentation and pathogenesis of a macaque lymphocryptoviral-associated B-cell lymphoma in a cynomolgus monkey.Vet Clin Pathol2020
33283855Accurate assembly of the olive baboon (Papio anubis) genome using long-read and Hi-C data.Gigascience2020
33205067Elevated Serum Amino Acids Induce a Subpopulation of Alpha Cells to Initiate Pancreatic Neuroendocrine Tumor Formation.Cell Rep Med2020
31222070Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy.Sci Rep2019
31881983S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis.Breast Cancer Res2019
31222070Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy.Sci Rep2019
31416423Evaluating the quality of the 1000 genomes project data.BMC Genomics2019
31881983S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis.Breast Cancer Res2019
31416423Evaluating the quality of the 1000 genomes project data.BMC Genomics2019
29786090CRISPR off-target analysis in genetically engineered rats and mice.Nat Methods2018
29884728An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors.Cancer Discov2018
30449325Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations.Cancer Cell2018
29760222ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy.Clin Cancer Res2018
29596465Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.PLoS One2018
29786090CRISPR off-target analysis in genetically engineered rats and mice.Nat Methods2018
29884728An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors.Cancer Discov2018
30449325Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations.Cancer Cell2018
29596465Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.PLoS One2018
29760222ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy.Clin Cancer Res2018
28887438Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia.J Cell Biol2017
28887438Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia.J Cell Biol2017
28361918Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types.Sci Rep2017
28361918Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types.Sci Rep2017
26700806Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function.Nature2016
26928227Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.Nat Genet2016
26700806Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function.Nature2016
26928227Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.Nat Genet2016
25401301Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.Nat Genet2015
25401301Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.Nat Genet2015
25485619A comprehensive transcriptional portrait of human cancer cell lines.Nat Biotechnol2015
25897122The BioMart community portal: an innovative alternative to large, centralized data repositories.Nucleic Acids Res2015
25962591Erratum to: Modeling precision treatment of breast cancer.Genome Biol2015
25897122The BioMart community portal: an innovative alternative to large, centralized data repositories.Nucleic Acids Res2015
25962591Erratum to: Modeling precision treatment of breast cancer.Genome Biol2015
25485619A comprehensive transcriptional portrait of human cancer cell lines.Nat Biotechnol2015
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Collaborators

Paul T Spellman
Oregon Health & Science University Hospital.
Co-authored papers 8
Peter M Haverty
Co-authored papers 6
Joe W Gray
Oregon Health and Science University
Co-authored papers 6
Yves Moreau
KU Leuven - University of Leuven
Co-authored papers 5
Lakshmi Jakkula
Co-authored papers 5
Thong T Nguyen
Gladstone Institute of Virology
Co-authored papers 4
Eric A Collisson
University of California san francisco
Co-authored papers 4
Robert Gentleman
Center for Computational Biomedicine, Harvard Medical School
Co-authored papers 3
Ron Firestein
Co-authored papers 3
Alvis Brazma
European Bioinformatics Institute
Co-authored papers 3
Elizabeth Purdom
Co-authored papers 3
James E Korkola
Co-authored papers 3
Pui-Yan Kwok
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 3
Raymond J Cho
University of California san francisco
Co-authored papers 3
Laura M Heiser
Oregon Health Sciences University
Co-authored papers 3
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
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John Z Sanborn
Co-authored papers 2
Leslie Cope
Johns Hopkins University School of Medicine
Co-authored papers 2
Ugis Sarkans
Co-authored papers 2
Tao Wang
University of Texas Southwestern Medical Center
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Oana M Enache
Co-authored papers 2
Wolfgang Huber
Technische Universitat Munchen
Co-authored papers 2
Kanika Bajaj
Genentech Inc.
Co-authored papers 2
Heidi S Feiler
Co-authored papers 2
Malachi Griffith
Washington University
Co-authored papers 2
Obi L Griffith
Washington University
Co-authored papers 2
Raphael Bueno
Co-authored papers 2
Terence P Speed
Walter and Eliza Hall Institute of Medical Research
Co-authored papers 2
Bart De Moor
STADIUS Center for Dynamical Systems
Co-authored papers 2
Qing-Rong Chen
Center for Biomedical Informatics and Information Technology
Co-authored papers 2
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