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Author Details

Fernando Rodrigues-Lima
Universite Paris Cite, CNRS
1995
117
31
PMIDPaper TitleJournal TitlePublished Year
37975232U2AF1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review).Oncol Rep2024
35875939Interplay between EGFR, E-cadherin, and PTP1B in epidermal homeostasis.Tissue Barriers2023
37770591Author Correction: CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.Nat Commun2023
37059817Legionella para-effectors target chromatin and promote bacterial replication.Nat Commun2023
36805080The Addiction-Susceptibility TaqIA/Ankk1 Controls Reward and Metabolism Through D<sub>2</sub> Receptor-Expressing Neurons.Biol Psychiatry2023
36737440Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation.Nat Commun2023
34806245Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy.Protein Sci2022
35806064Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma.Int J Mol Sci2022
35806030Human Protein Tyrosine Phosphatase 1B (PTP1B): From Structure to Clinical Inhibitor Perspectives.Int J Mol Sci2022
35575086UNC45A deficiency causes microvillus inclusion disease-like phenotype by impairing myosin VB-dependent apical trafficking.J Clin Invest2022
35871293HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia.Nucleic Acids Res2022
36380082Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance.Commun Biol2022
36385105CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.Nat Commun2022
36076604SPARC in hematologic malignancies and novel technique for hematological disease with its abnormal expression.Biomed Pharmacother2022
35132614Systemic inflammatory syndrome in children with FARSA deficiency.Clin Genet2022
32855277Oxidative stress activates red cell adhesion to laminin in sickle cell disease.Haematologica2021
34568314Network Pharmacology and Experimental Validation Reveal the Effects of Chidamide Combined With Aspirin on Acute Myeloid Leukemia-Myelodysplastic Syndrome Cells Through PI3K/AKT Pathway.Front Cell Dev Biol2021
34218775Chidamide Inhibits Cell Proliferation via the PI3K/AKT Pathway in K562 Cells Based on Network Pharmacology and Experimental Validation.Curr Pharm Des2021
34243013Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play.Transl Oncol2021
34266924The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3).Mol Pharmacol2021
34050145Dynamic methylation of histone H3K18 in differentiating Theileria parasites.Nat Commun2021
33278510Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues.Free Radic Biol Med2021
32089267From transglutaminases (TGs) to arylamine N-acetyltransferases (NATs): Insight into the role of a spatially conserved aromatic amino acid position in the active site of these two families of enzymes.Biochem Biophys Res Commun2020
30883722A readout of metabolic efficiency in arylamine N-acetyltransferase-deficient mice reveals minor energy metabolism changes.FEBS Lett2019
31667807The Structure and the Regulation of Glycogen Phosphorylases in Brain.Adv Neurobiol2019
31221825T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide.Mol Pharmacol2019
31248982Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling.J Biol Chem2019
29650953HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis.Nat Commun2018
29434250DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives.Sci Rep2018
27782369The structure of brain glycogen phosphorylase-from allosteric regulation mechanisms to clinical perspectives.FEBS J2017
28288979<i>Crebbp</i> loss cooperates with <i>Bcl2</i> overexpression to promote lymphoma in mice.Blood2017
28674152Human Arylamine <i>N</i>-Acetyltransferase 1 Is Inhibited by the Dithiocarbamate Pesticide Thiram.Mol Pharmacol2017
27846346Xenobiotic-metabolizing enzymes in Bacillus anthracis: molecular and functional analysis of a truncated arylamine N-acetyltransferase isozyme.Br J Pharmacol2017
27965358Molecular Mechanisms of Allosteric Inhibition of Brain Glycogen Phosphorylase by Neurotoxic Dithiocarbamate Chemicals.J Biol Chem2017
26840026Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens.Oncotarget2016
27660393An Isozyme-specific Redox Switch in Human Brain Glycogen Phosphorylase Modulates Its Allosteric Activation by AMP.J Biol Chem2016
27402852Insights into Brain Glycogen Metabolism: THE STRUCTURE OF HUMAN BRAIN GLYCOGEN PHOSPHORYLASE.J Biol Chem2016
25391334Effects of pesticide chemicals on the activity of metabolic enzymes: focus on thiocarbamates.Expert Opin Drug Metab Toxicol2015
26099937An acetyltransferase assay for CREB-binding protein based on reverse phase-ultra-fast liquid chromatography of fluorescent histone H3 peptides.Anal Biochem2015
26040922A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2).Sci Rep2015
26068093Screen for soil fungi highly resistant to dichloroaniline uncovers mostly Fusarium species.Fungal Genet Biol2015
25664736Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A.Acta Crystallogr D Biol Crystallogr2015
25224404Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites.Arch Toxicol2015
24269889Skeletal muscle glycogen phosphorylase is irreversibly inhibited by mercury: molecular, cellular and kinetic aspects.FEBS Lett2014
25372695Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus: differences from other mycobacterial isoforms and implications for selective inhibition.Acta Crystallogr D Biol Crystallogr2014
24823794From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2.PLoS One2014
24683030Intracellular signal modulation by nanomaterials.Adv Exp Med Biol2014
24374000A high-performance liquid chromatography assay for Dyrk1a, a Down syndrome-associated kinase.Anal Biochem2014
24328723Arylamine N-acetyltransferases: a structural perspective. Comments regarding the BJP paper by Zhou et al., 2013.Br J Pharmacol2014
23357313Comparative analysis of interactions of RASSF1-10.Adv Biol Regul2013
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Collaborators

Universite de Paris, CNRS
Co-authored papers 76
INSERM UMR-S1124, Universite Paris Cite
Co-authored papers 20
Universite Paris Cite, CNRS
Co-authored papers 16
Shandong Jianzhu University
Co-authored papers 6
PSL Universite, CNRS
Co-authored papers 4
Universite PSL, LPC CNRS UMR8249
Co-authored papers 4
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
The South China University of Technology Comprehensive Cancer Center
Co-authored papers 2
UK Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge
Co-authored papers 2
Universite Paris Cite, CNRS
Co-authored papers 2
Universite de Paris, CNRS
Co-authored papers 2
Universite de Paris, CNRS
Co-authored papers 2
University of Toronto
Co-authored papers 2
Virginia Commonwealth University
Co-authored papers 2
The Francis Crick Institute
Co-authored papers 2
University of Lorraine
Co-authored papers 1
Assistance Publique des Hopitaux de Paris (AP-HP)
Co-authored papers 1
The University of Edinburgh
Co-authored papers 1
University of Nebraska Medical Center
Co-authored papers 1
Saint-Louis Hospital
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Institute of Structural and Molecular Biology, University of London
Co-authored papers 1
Cancer Research Centre (IBMCC/CSIC/USAL/IBSAL)
Co-authored papers 1
University of California los angeles
Co-authored papers 1
German Center for Diabetes Research (DZD e.V.)
Co-authored papers 1
Oncode Institute, The Netherlands Cancer Institute
Co-authored papers 1
Universite de Paris, CNRS
Co-authored papers 1
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 1
University Health Network
Co-authored papers 1
University of Toronto
Co-authored papers 1