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Author Details

Peter Holmans
1993
286
90
PMIDPaper TitleJournal TitlePublished Year
37551635A polygenic resilience score moderates the genetic risk for schizophrenia: Replication in 18,090 cases and 28,114 controls from the Psychiatric Genomics Consortium.Am J Med Genet B Neuropsychiatr Genet2024
36914811Family-based analysis of the contribution of rare and common genetic variants to school performance in schizophrenia.2023
37744023Pathway-specific polygenic scores for Alzheimer's disease are associated with changes in brain structure in younger and older adults.2023
37974536Relevance of Multiple Sclerosis Severity Genotype in Predicting Disease Course: A Real-World Cohort.2023
36652379The relationship between case-control differential gene expression from brain tissue and genetic associations in schizophrenia.2023
37272871Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements.2023
37207016A tutorial comparing different covariate balancing methods with an application evaluating the causal effects of substance use treatment programs for adolescents.2023
36577842Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer's disease through polygenic risk and RNA sequencing.2023
37437579Specificity of polygenic signatures across symptom dimensions in bipolar disorder: an analysis of UK Bipolar Disorder Research Network data.2023
35325614Genetic modifiers of Huntington disease differentially influence motor and cognitive domains.American Journal of Human Genetics2022
35396580Mapping genomic loci implicates genes and synaptic biology in schizophrenia.Nature2022
35531971Developmental disruption to the cortical transcriptome and synaptosome in a model of SETD1A loss-of-function.Hum Mol Genet2022
36044200Genetic Liabilities Differentiating Bipolar Disorder, Schizophrenia, and Major Depressive Disorder, and Phenotypic Heterogeneity in Bipolar Disorder.JAMA Psychiatry2022
35379992New insights into the genetic etiology of Alzheimer's disease and related dementias.Nat Genet2022
35379994Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset.Nature Neuroscience2022
35879306Polygenic resilience scores capture protective genetic effects for Alzheimer's disease.Transl Psychiatry2022
35729184Both cis and trans-acting genetic factors drive somatic instability in female carriers of the FMR1 premutation.Scientific Reports2022
35976659Ultrarare Coding Variants and Cognitive Function in Schizophrenia.JAMA Psychiatry2022
36519153Intellectual enrichment and genetic modifiers of cognition and brain volume in Huntington's disease.2022
36532292The impact of genetic risk for Alzheimer's disease on the structural brain networks of young adults.2022
32515721Examining pathways between genetic liability for schizophrenia and patterns of tobacco and cannabis use in adolescence.Psychol Med2022
35019943Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.JAMA Psychiatry2022
34954139A Computational Analysis of Abnormal Belief Updating Processes and Their Association With Psychotic Experiences and Childhood Trauma in a UK Birth Cohort.2022
34487047Cognitive Decline in Alzheimer's Disease Is Not Associated with APOE.Journal of Alzheimer's Disease2021
32015465Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion.Mol Psychiatry2021
34180418Association Analysis of Chromosome X to Identify Genetic Modifiers of Huntington's Disease.Journal of Huntington's disease2021
34294785Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer's disease.Scientific Reports2021
33965196Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity.Biological Psychiatry2021
33959712Defining functional variants associated with Alzheimer's disease in the induced immune response.Brain Communications2021
33579866What is the Pathogenic CAG Expansion Length in Huntington's Disease?Journal of Huntington's disease2021
33579862Huntington's Disease Pathogenesis: Two Sequential Components.Journal of Huntington's disease2021
34112972Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.Mol Psychiatry2021
33678419Rare Copy Number Variants Are Associated With Poorer Cognition in Schizophrenia.Biological Psychiatry2021
34002096Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.Nat Genet2021
33837784Risk Factors, Clinical Features, and Polygenic Risk Scores in Schizophrenia and Schizoaffective Disorder Depressive-Type.Schizophrenia Bulletin2021
34347035Associations Between Schizophrenia Polygenic Liability, Symptom Dimensions, and Cognitive Ability in Schizophrenia.JAMA Psychiatry2021
33077856Genetic association of FMRP targets with psychiatric disorders.Molecular Psychiatry2021
34504065Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations.Nat Commun2021
31206164The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia.Schizophr Bull2020
31906710A Population-Based Cohort Study Examining the Incidence and Impact of Psychotic Experiences From Childhood to Adulthood, and Prediction of Psychotic Disorder.American Journal of Psychiatry2020
31691811A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia.Hum Mol Genet2020
31767120Characterization of Single Gene Copy Number Variants in Schizophrenia.Biol Psychiatry2020
32154840Reply: The repeat variant in MSH3 is not a genetic modifier for spinocerebellar ataxia type 3 and Friedreich's ataxia.Brain2020
32087949Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington's Disease.Biol Psychiatry2020
32589923Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.American Journal of Human Genetics2020
32998554Using Genetics to Increase Specificity of Outcome Prediction in Psychiatric Disorders: Prospects for Progression.American Journal of Psychiatry2020
30718481Dynamic expression of genes associated with schizophrenia and bipolar disorder across development.Transl Psychiatry2019
31740837Comparative genetic architectures of schizophrenia in East Asian and European populations.Nat Genet2019
31607598A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes.EBioMedicine2019
31553412Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits.JAMA Psychiatry2019
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Stanford University School of Medicine
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Institute of Human Genetics, University Hospital Bonn
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University of North Carolina at Chapel Hill
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Cardiff University
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Massachusetts General Hospital and Harvard Medical School
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Center for Psychiatric Genetics, NorthShore University HealthSystem
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Virginia Commonwealth University
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Brigham and Women's Hospital
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Washington University School of Medicine
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Institute of Psychiatry, King's College London
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