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Author Details
Full Name
Shiaw-Lin Wu
Affiliation
BioAnalytix Inc.
ORCID
Career Start Year
1986
Papers
75
H Index
32
Expertise
CM4AI Collaborator
Emma Lundberg (CM4AI)
PMID
Paper Title
Journal Title
Published Year
32420732
Impact of Glycosylation on the Comparability of the Higher-Order Structures in Idursulfase by Hydrogen-Deuterium Exchange Mass Spectrometry.
Anal Chem
2020
31446487
The application of HPLC/MS analysis with a multi-enzyme digest strategy to characterize different interferon product variants produced from Pichia pastoris.
Amino Acids
2019
30272677
On-demand manufacturing of clinical-quality biopharmaceuticals.
Nat Biotechnol
2018
27776829
Comparative study of profiling post-translational modifications of a circulating antibody drug in human with different capture reagents.
Biologicals
2017
28096095
Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.
Blood
2017
29096433
Integrated Bottom-Up and Top-Down Liquid Chromatography-Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products.
Anal Chem
2017
28921955
Characterization of Site-Specific Glycosylation in Influenza A Virus Hemagglutinin Produced by Spodoptera frugiperda Insect Cell Line.
Anal Chem
2017
27291648
Identification of Low Abundant Isomeric N-Glycan Structures in Biological Therapeutics by LC/MS.
Anal Chem
2016
25015948
Aberrant serum immunoglobulin G glycosylation in chronic hepatitis B is associated with histological liver damage and reversible by antiviral therapy.
J Infect Dis
2015
26435392
Integrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues.
J Proteome Res
2015
25987564
Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation.
J Biol Chem
2015
25281793
Development of LC-MS methods for quantitation of hepcidin and demonstration of siRNA-mediated hepcidin suppression in serum.
J Pharmacol Toxicol Methods
2015
24111759
Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.
J Proteome Res
2014
25300029
Identification of novel glycans with disialylated structures in α3 integrin from mouse kidney cells with the phenotype of polycystic kidney disease.
J Proteome Res
2014
24849600
Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments.
J Biol Chem
2014
23371026
Identification of potential glycan cancer markers with sialic acid attached to sialic acid and up-regulated fucosylated galactose structures in epidermal growth factor receptor secreted from A431 cell line.
Mol Cell Proteomics
2013
23647160
Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer.
J Proteome Res
2013
23751726
Comparability analysis of anti-CD20 commercial (rituximab) and RNAi-mediated fucosylated antibodies by two LC-MS approaches.
MAbs
2013
23563225
A global comparability approach for biosimilar monoclonal antibodies using LC-tandem MS based proteomics.
J Pharm Biomed Anal
2013
23208745
Complete mapping of a cystine knot and nested disulfides of recombinant human arylsulfatase A by multi-enzyme digestion and LC-MS analysis using CID and ETD.
J Am Soc Mass Spectrom
2013
23172735
Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals.
Biotechnol Prog
2013
23259914
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17.
J Proteome Res
2013
22170055
Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope.
J Biol Chem
2012
23022358
Reversion of the ErbB malignant phenotype and the DNA damage response.
Exp Mol Pathol
2012
22813742
Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.
Cell Rep
2012
22390546
LC-MS analysis of polyclonal human anti-Neu5Gc xeno-autoantibodies immunoglobulin G Subclass and partial sequence using multistep intravenous immunoglobulin affinity purification and multienzymatic digestion.
Anal Chem
2012
21082378
Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics.
Methods Mol Biol
2011
21312369
Characterization of the proteases involved in the N-terminal clipping of glucagon-like-peptide-1-antibody fusion proteins.
Biotechnol Prog
2011
21428412
Characterization and comparison of disulfide linkages and scrambling patterns in therapeutic monoclonal antibodies: using LC-MS with electron transfer dissociation.
Anal Chem
2011
19579057
Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton.
Cell Stress Chaperones
2010
20552988
Characterization of the glycosylation occupancy and the active site in the follow-on protein therapeutic: TNK-tissue plasminogen activator.
Anal Chem
2010
20481521
Identification of the unpaired cysteine status and complete mapping of the 17 disulfides of recombinant tissue plasminogen activator using LC-MS with electron transfer dissociation/collision induced dissociation.
Anal Chem
2010
18945436
Hydrophilic interaction 10 microm I.D. porous layer open tubular columns for ultratrace glycan analysis by liquid chromatography-mass spectrometry.
J Chromatogr A
2009
19788250
Development of different analysis platforms with LC-MS for pharmacokinetic studies of protein drugs.
Anal Chem
2009
19117448
Mass spectrometric determination of disulfide linkages in recombinant therapeutic proteins using online LC-MS with electron-transfer dissociation.
Anal Chem
2009
19224592
Mass spectrometric analysis of innovator, counterfeit, and follow-on recombinant human growth hormone.
Biotechnol Prog
2009
19215933
Study of the human plasma proteome of rheumatoid arthritis.
J Chromatogr A
2009
18383016
Two-dimensional strong cation exchange/porous layer open tubular/mass spectrometry for ultratrace proteomic analysis using a 10 microm id poly(styrene- divinylbenzene) porous layer open tubular column with an on-line triphasic trapping column.
Electrophoresis
2008
18720982
Comprehensive characterization of heat shock protein 27 phosphorylation in human endothelial cells stimulated by the microbial dithiole thiolutin.
J Proteome Res
2008
18481836
Analysis of mouse brain microvascular endothelium using immuno-laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform-mass spectrometry proteomics platform.
Electrophoresis
2008
17441747
A new algorithm using cross-assignment for label-free quantitation with LC-LTQ-FT MS.
J Proteome Res
2007
17902640
Proteomic analysis of high-grade dysplastic cervical cells obtained from ThinPrep slides using laser capture microdissection and mass spectrometry.
J Proteome Res
2007
17900180
On-line LC-MS approach combining collision-induced dissociation (CID), electron-transfer dissociation (ETD), and CID of an isolated charge-reduced species for the trace-level characterization of proteins with post-translational modifications.
J Proteome Res
2007
17625912
On-line 1D and 2D porous layer open tubular/LC-ESI-MS using 10-microm-i.d. poly(styrene-divinylbenzene) columns for ultrasensitive proteomic analysis.
Anal Chem
2007
17263319
Ultratrace LC/MS proteomic analysis using 10-microm-i.d. Porous layer open tubular poly(styrene-divinylbenzene) capillary columns.
Anal Chem
2007
17442327
Ultratrace liquid chromatography/mass spectrometry analysis of large peptides with post-translational modifications using narrow-bore poly(styrene-divinylbenzene) monolithic columns and extended range proteomic analysis.
J Chromatogr A
2007
16497783
Approaches to the study of N-linked glycoproteins in human plasma using lectin affinity chromatography and nano-HPLC coupled to electrospray linear ion trap--Fourier transform mass spectrometry.
Glycobiology
2006
16799092
Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA).
Mol Cell Proteomics
2006
16739974
Monitoring of glycoprotein products in cell culture lysates using lectin affinity chromatography and capillary HPLC coupled to electrospray linear ion trap-Fourier transform mass spectrometry (LTQ/FTMS).
Biotechnol Prog
2006
16920285
Glycation of interferon-beta-1b and human serum albumin in a lyophilized glucose formulation. Part III: application of proteomic analysis to the manufacture of biological drugs.
Int J Pharm
2006
1 - 50 of 75
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