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Author Details

Shiaw-Lin Wu
BioAnalytix Inc.
1986
75
32
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
32420732Impact of Glycosylation on the Comparability of the Higher-Order Structures in Idursulfase by Hydrogen-Deuterium Exchange Mass Spectrometry.Anal Chem2020
31446487The application of HPLC/MS analysis with a multi-enzyme digest strategy to characterize different interferon product variants produced from Pichia pastoris.Amino Acids2019
30272677On-demand manufacturing of clinical-quality biopharmaceuticals.Nat Biotechnol2018
27776829Comparative study of profiling post-translational modifications of a circulating antibody drug in human with different capture reagents.Biologicals2017
28096095Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.Blood2017
29096433Integrated Bottom-Up and Top-Down Liquid Chromatography-Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products.Anal Chem2017
28921955Characterization of Site-Specific Glycosylation in Influenza A Virus Hemagglutinin Produced by Spodoptera frugiperda Insect Cell Line.Anal Chem2017
27291648Identification of Low Abundant Isomeric N-Glycan Structures in Biological Therapeutics by LC/MS.Anal Chem2016
25015948Aberrant serum immunoglobulin G glycosylation in chronic hepatitis B is associated with histological liver damage and reversible by antiviral therapy.J Infect Dis2015
26435392Integrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues.J Proteome Res2015
25987564Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation.J Biol Chem2015
25281793Development of LC-MS methods for quantitation of hepcidin and demonstration of siRNA-mediated hepcidin suppression in serum.J Pharmacol Toxicol Methods2015
24111759Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.J Proteome Res2014
25300029Identification of novel glycans with disialylated structures in α3 integrin from mouse kidney cells with the phenotype of polycystic kidney disease.J Proteome Res2014
24849600Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments.J Biol Chem2014
23371026Identification of potential glycan cancer markers with sialic acid attached to sialic acid and up-regulated fucosylated galactose structures in epidermal growth factor receptor secreted from A431 cell line.Mol Cell Proteomics2013
23647160Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer.J Proteome Res2013
23751726Comparability analysis of anti-CD20 commercial (rituximab) and RNAi-mediated fucosylated antibodies by two LC-MS approaches.MAbs2013
23563225A global comparability approach for biosimilar monoclonal antibodies using LC-tandem MS based proteomics.J Pharm Biomed Anal2013
23208745Complete mapping of a cystine knot and nested disulfides of recombinant human arylsulfatase A by multi-enzyme digestion and LC-MS analysis using CID and ETD.J Am Soc Mass Spectrom2013
23172735Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals.Biotechnol Prog2013
23259914A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17.J Proteome Res2013
22170055Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope.J Biol Chem2012
23022358Reversion of the ErbB malignant phenotype and the DNA damage response.Exp Mol Pathol2012
22813742Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.Cell Rep2012
22390546LC-MS analysis of polyclonal human anti-Neu5Gc xeno-autoantibodies immunoglobulin G Subclass and partial sequence using multistep intravenous immunoglobulin affinity purification and multienzymatic digestion.Anal Chem2012
21082378Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics.Methods Mol Biol2011
21312369Characterization of the proteases involved in the N-terminal clipping of glucagon-like-peptide-1-antibody fusion proteins.Biotechnol Prog2011
21428412Characterization and comparison of disulfide linkages and scrambling patterns in therapeutic monoclonal antibodies: using LC-MS with electron transfer dissociation.Anal Chem2011
19579057Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton.Cell Stress Chaperones2010
20552988Characterization of the glycosylation occupancy and the active site in the follow-on protein therapeutic: TNK-tissue plasminogen activator.Anal Chem2010
20481521Identification of the unpaired cysteine status and complete mapping of the 17 disulfides of recombinant tissue plasminogen activator using LC-MS with electron transfer dissociation/collision induced dissociation.Anal Chem2010
18945436Hydrophilic interaction 10 microm I.D. porous layer open tubular columns for ultratrace glycan analysis by liquid chromatography-mass spectrometry.J Chromatogr A2009
19788250Development of different analysis platforms with LC-MS for pharmacokinetic studies of protein drugs.Anal Chem2009
19117448Mass spectrometric determination of disulfide linkages in recombinant therapeutic proteins using online LC-MS with electron-transfer dissociation.Anal Chem2009
19224592Mass spectrometric analysis of innovator, counterfeit, and follow-on recombinant human growth hormone.Biotechnol Prog2009
19215933Study of the human plasma proteome of rheumatoid arthritis.J Chromatogr A2009
18383016Two-dimensional strong cation exchange/porous layer open tubular/mass spectrometry for ultratrace proteomic analysis using a 10 microm id poly(styrene- divinylbenzene) porous layer open tubular column with an on-line triphasic trapping column.Electrophoresis2008
18720982Comprehensive characterization of heat shock protein 27 phosphorylation in human endothelial cells stimulated by the microbial dithiole thiolutin.J Proteome Res2008
18481836Analysis of mouse brain microvascular endothelium using immuno-laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform-mass spectrometry proteomics platform.Electrophoresis2008
17441747A new algorithm using cross-assignment for label-free quantitation with LC-LTQ-FT MS.J Proteome Res2007
17902640Proteomic analysis of high-grade dysplastic cervical cells obtained from ThinPrep slides using laser capture microdissection and mass spectrometry.J Proteome Res2007
17900180On-line LC-MS approach combining collision-induced dissociation (CID), electron-transfer dissociation (ETD), and CID of an isolated charge-reduced species for the trace-level characterization of proteins with post-translational modifications.J Proteome Res2007
17625912On-line 1D and 2D porous layer open tubular/LC-ESI-MS using 10-microm-i.d. poly(styrene-divinylbenzene) columns for ultrasensitive proteomic analysis.Anal Chem2007
17263319Ultratrace LC/MS proteomic analysis using 10-microm-i.d. Porous layer open tubular poly(styrene-divinylbenzene) capillary columns.Anal Chem2007
17442327Ultratrace liquid chromatography/mass spectrometry analysis of large peptides with post-translational modifications using narrow-bore poly(styrene-divinylbenzene) monolithic columns and extended range proteomic analysis.J Chromatogr A2007
16497783Approaches to the study of N-linked glycoproteins in human plasma using lectin affinity chromatography and nano-HPLC coupled to electrospray linear ion trap--Fourier transform mass spectrometry.Glycobiology2006
16799092Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA).Mol Cell Proteomics2006
16739974Monitoring of glycoprotein products in cell culture lysates using lectin affinity chromatography and capillary HPLC coupled to electrospray linear ion trap-Fourier transform mass spectrometry (LTQ/FTMS).Biotechnol Prog2006
16920285Glycation of interferon-beta-1b and human serum albumin in a lyophilized glucose formulation. Part III: application of proteomic analysis to the manufacture of biological drugs.Int J Pharm2006
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Collaborators

Northeastern University
Co-authored papers 40
Genome Opinion Inc.
Co-authored papers 5
Stanford University
Co-authored papers 5
Dongzhimen Hospital, Beijing University of Chinese Medicine
Co-authored papers 4
College of Life Sciences and Biotechnology, Yonsei University
Co-authored papers 3
and School of Public Health, University of Michigan ann arbor
Co-authored papers 3
Macquarie University
Co-authored papers 3
University of Manitoba
Co-authored papers 3
Seul-Ki Jeong Neurology Clinic
Co-authored papers 3
Stanford University
Co-authored papers 2
Broad Institute of Harvard and MIT
Co-authored papers 2
University of Michigan Medical School ann arbor
Co-authored papers 2
Beijing Mental Health Care Institute
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Co-authored papers 2
Thomas Jefferson University Hospital
Co-authored papers 2
University of Texas MD Anderson Cancer Center
Co-authored papers 2
Korea Advanced Institute of Science and Technology (KAIST)
Co-authored papers 2
Co-authored papers 2
Weill Cornell School of Medicine
Co-authored papers 2
Michigan State University
Co-authored papers 1
Center for Biomedical Mass Spectrometry, Boston University
Co-authored papers 1
University of Geneva
Co-authored papers 1
Monash University
Co-authored papers 1
Institute for Systems Genetics, NYU Grossman School of Medicine
Co-authored papers 1
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences
Co-authored papers 1
Co-authored papers 1
Complex Carbohydrate Research Center, University of Georgia
Co-authored papers 1
Alnylam Pharmaceuticals
Co-authored papers 1
Yonsei University
Co-authored papers 1