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Author Details

Arnaud Jacquel
Universite Cote d'Azur, INSERM U5
1995
82
34
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36375119BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1.Blood2023
37143666The generation, activation, and polarization of monocyte-derived macrophages in human malignancies.Front Immunol2023
36585521High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2::GLIS2 pediatric leukemia.Leukemia2023
36835566Caspase Inhibition Modulates Monocyte-Derived Macrophage Polarization in Damaged Tissues.Int J Mol Sci2023
34986346AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia.Cell Rep2022
35641638REDD1 is a gatekeeper of murine hematopoietic stem cell functions during stress responses.Leukemia2022
35668193P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.Nat Cancer2022
33413419ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity.Mol Cancer2021
33683342Heterogeneous NLRP3 inflammasome signature in circulating myeloid cells as a biomarker of COVID-19 severity.Blood Adv2021
33504341Correction to: ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity.Mol Cancer2021
35251769Reprogramming monocyte-derived macrophages through caspase inhibition.Oncoimmunology2021
34099492Dual Covalent Inhibition of PKM and IMPDH Targets Metabolism in Cutaneous Metastatic Melanoma.Cancer Res2021
33432150Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice.Nat Microbiol2021
32160545ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.Cell Rep2020
32665699Retraction Note: LAMP2 expression dictates azacytidine response and prognosis in MDS/AML.Leukemia2020
32707827Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression.Cancers (Basel)2020
30571969Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice.J Invest Dermatol2019
31623164Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies.Cells2019
31097717Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo.Nat Commun2019
30607021LAMP2 expression dictates azacytidine response and prognosis in MDS/AML.Leukemia2019
28914261RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.Leukemia2018
30566860Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance.Cell Rep2018
30274374Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation.Int J Mol Sci2018
29391601The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.Oncogene2018
29321503IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.Sci Rep2018
28850564CXCL7 is a predictive marker of sunitinib efficacy in clear cell renal cell carcinomas.Br J Cancer2017
28367807[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies].Med Sci (Paris)2017
29423056Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia.Oncotarget2017
29541386ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.Oncotarget2017
27027430Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death.Oncotarget2016
27455953BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice.J Exp Med2016
27388216DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes.Diabetes2016
25781937Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia.PLoS Pathog2015
26601252Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia.Sci Adv2015
26029847The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML.Autophagy2015
24504023Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes.Leukemia2014
25058423A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function.Cell Death Dis2014
25051369The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.Oncotarget2014
25105565CD271 is an imperfect marker for melanoma initiating cells.Oncotarget2014
24744249cIAPs and XIAP reduce RIPKs to silence.Blood2014
24962689Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines.Oncotarget2014
23394086How recent advances in high-risk myelodysplastic syndrome physiopathology may impact future treatments.Curr Pharm Des2013
24014241Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.Blood2013
23673326Ponatinib circumvents all types of imatinib resistance in chronic myelogenous leukemia cell lines.Cell Cycle2013
22577154BCL2L10 is a predictive factor for resistance to azacitidine in MDS and AML patients.Oncotarget2012
23518796Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway.Oncotarget2012
23238683All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to ponatinib.Oncotarget2012
23071785Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling.PLoS One2012
22751215Proper macrophagic differentiation requires both autophagy and caspase activation.Autophagy2012
22452982Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.Blood2012
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Collaborators

Patrick Auberger
Universite Cote d'Azur, INSERM U5
Co-authored papers 64
Alexandre Puissant
Universite de Paris, INSERM, CNRS
Co-authored papers 19
Thomas Cluzeau
Universite Nice Cote d'azur, CHU de Nice
Co-authored papers 14
Paul Chaintreuil
Universite Cote d'Azur, Institut National de la Sante et de la Recherche Medicale
Co-authored papers 7
Nina Fenouille
Universite Paris Cite, INSERM, CNRS
Co-authored papers 6
Stoyan Ivanov
Co-authored papers 3
Gaetano Sodaro
Universite Paris Cite, INSERM, CNRS
Co-authored papers 2
Christopher F Bassil
Duke University School of Medicine Durham
Co-authored papers 2
Thomas Strub
Co-authored papers 2
Claude Preudhomme
Lille University Hospital, INSERM UMR-S7, CNRS UMR9020, Lille University.
Co-authored papers 2
Paul-Arthur Meslin
Universite de Paris, INSERM, CNRS
Co-authored papers 1
Soheil Meshinchi
Fred Hutchinson Cancer Research Centre
Co-authored papers 1
Camille Vaganay
Universite de Paris, INSERM, CNRS
Co-authored papers 1
Lina Benajiba
Universite de Paris, Inserm CIC 1427
Co-authored papers 1
David A Rizzieri
Duke University Medical Center
Co-authored papers 1
Elisabeth Christians
Co-authored papers 1
Xinghai Li
Duke University
Co-authored papers 1
Anton M Jetten
National Institutes of Health
Co-authored papers 1
Timothy S Pardee
Comprehensive Cancer Center of Wake Forest Baptist Health, Medical Center Boulevard
Co-authored papers 1
Nan Wang
Co-authored papers 1
Kevin H Lin
Duke University
Co-authored papers 1
Hazel X Ang
Duke University School of Medicine
Co-authored papers 1
Alan R Tall
Co-authored papers 1
Frank Ling
Universite de Paris, INSERM, CNRS
Co-authored papers 1
Jacob P Hoj
Duke University
Co-authored papers 1
Zhecheng Sheng
Duke University
Co-authored papers 1
Raphael Itzykson
Universite Paris Cite, INSERM, CNRS
Co-authored papers 1
Marie Verbanck
Co-authored papers 1
Jean-Fran??ois Benoist
Hopital Universitaire Necker-Enfants Malades, Assistance Publique - Hopitaux de Paris
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Camille Lobry
INSERM U1170, Universite Paris Saclay
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Release 1.2