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Author Details

Alan Christoffels
1999
94
28
PMIDPaper TitleJournal TitlePublished Year
37161068A pan-African pathogen genomics data sharing platform to support disease outbreaks.Nat Med2023
37093793Transforming RNA-Seq gene expression to track cancer progression in the multi-stage early to advanced-stage cancer development.2023
36865386Investigation of distinct gene expression profile patterns that can improve the classification of intermediate-risk prognosis in AML patients.2023
36851690Using Multiplex Amplicon PCR Technology to Efficiently and Timely Generate Rift Valley Fever Virus Sequence Data for Genomic Surveillance.2023
35138128The COMBAT-TB Workbench: Making Powerful Mycobacterium tuberculosis Bioinformatics Accessible.mSphere2022
35850574Genomic surveillance of Rift Valley fever virus: from sequencing to lineage assignment.BMC Genomics2022
36699416The developmentally dynamic microRNA transcriptome of tsetse flies, vectors of animal trypanosomiasis.2022
35299952Current Status of Next-Generation Sequencing Approaches for Candidate Gene Discovery in Familial Parkinson´s Disease.Frontiers in Genetics2022
35298540microRNA profile of Hermetia illucens (black soldier fly) and its implications on mass rearing.PLoS ONE2022
35309124High Resolution HLA ⿼A, ⿼B, ⿼C, ⿼DRB1, ⿼DQA1, and ⿼DQB1 Diversity in South African Populations.Frontiers in Genetics2022
35249471Upregulation of , , and predicts poor prognosis in pediatric acute myeloid leukemia patients with mutation.Leukemia and Lymphoma2022
35203542Repurposing Based Identification of Novel Inhibitors against MmpS5-MmpL5 Efflux Pump of : A Combined In Silico and In Vitro Study.Biomedicines2022
35169842Future-proofing and maximizing the utility of metadata: The PHA4GE SARS-CoV-2 contextual data specification package.Gigascience2022
34751044Predicting amplification of using CpG methylation biomarkers in neuroblastoma.Future Oncology2021
34209681Cheminformatic Characterization of Natural Antimicrobial Products for the Development of New Lead Compounds.Molecules2021
34208597Cheminformatic Profiling and Hit Prioritization of Natural Products with Activities against Methicillin-Resistant (MRSA).Molecules2021
33770142Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.PLoS ONE2021
34257588Evaluation of Protein Purification Techniques and Effects of Storage Duration on LC-MS/MS Analysis of Archived FFPE Human CRC Tissues.Pathology and Oncology Research2021
34727137In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c).PLoS ONE2021
34966662Effect of polyethylene glycol 20 000 on protein extraction efficiency of formalin-fixed paraffin-embedded tissues in South Africa.African Journal of Laboratory Medicine2021
34421882Transcriptomic Profile of in Response to an Imidazo[1,2-][1,2,4,5]tetrazine Reveals Its Possible Impact on Iron Metabolism.Frontiers in Microbiology2021
31504165COMBAT-TB-NeoDB: fostering tuberculosis research through integrative analysis using graph database technologies.2020
31908277Careful governance of African biobanks.Lancet, The2020
32163438A population model for the 2017/18 listeriosis outbreak in South Africa.PLoS ONE2020
33245713Identification of novel prognostic markers of survival time in high-risk neuroblastoma using gene expression profiles.Oncotarget2020
32581714Cellular and Molecular Targets of Waterbuck Repellent Blend Odors in Antennae of Newstead, 1910.Frontiers in Cellular Neuroscience2020
33134711Inhibiting CDK6 Activity by Quercetin Is an Attractive Strategy for Cancer Therapy.ACS Omega2020
32838350Accelerating genomics-based surveillance for COVID-19 response in Africa.Lancet Microbe, The2020
31121229Structure based identification of novel inhibitors against ATP synthase of Mycobacterium tuberculosis: A combined in silico and in vitro study.International Journal of Biological Macromolecules2019
30867456Designing novel possible kinase inhibitor derivatives as therapeutics against Mycobacterium tuberculosis: An in silico study.Scientific Reports2019
29850621Human Leukocyte Antigen-A, B, C, DRB1, and DQB1 Allele and Haplotype Frequencies in a Subset of 237 Donors in the South African Bone Marrow Registry.Journal of Immunology Research2018
30265702Predictive classifier models built from natural products with antimalarial bioactivity using machine learning approach.PLoS ONE2018
30475855Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c.PLoS ONE2018
29945178Prediction of human-Bacillus anthracis protein-protein interactions using multi-layer neural network.2018
29723308Correction: Cross-species multiple environmental stress responses: An integrated approach to identify candidate genes for multiple stress tolerance in sorghum (Sorghum bicolor (L.) Moench) and related model species.PLoS ONE2018
29590108Cross-species multiple environmental stress responses: An integrated approach to identify candidate genes for multiple stress tolerance in sorghum (Sorghum bicolor (L.) Moench) and related model species.PLoS ONE2018
29233967Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans.Nat Commun2017
28628859Structural and functional effects of nucleotide variation on the human TB drug metabolizing enzyme arylamine N-acetyltransferase 1.Journal of Molecular Graphics and Modelling2017
28802409Exploring the potential of T7 bacteriophage protein Gp2 as a novel inhibitor of mycobacterial RNA polymerase.Tuberculosis2017
28375759Baobab Laboratory Information Management System: Development of an Open-Source Laboratory Information Management System for Biobanking.Biopreservation and Biobanking2017
29273003An integrated and comparative approach towards identification, characterization and functional annotation of candidate genes for drought tolerance in sorghum (Sorghum bicolor (L.) Moench).BMC Genetics2017
27825380Identification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing.Malaria Journal2016
26845152The Development of Computational Biology in South Africa: Successes Achieved and Lessons Learnt.PLoS Comput Biol2016
26886411Genome-Wide Comparative Analysis of Chemosensory Gene Families in Five Tsetse Fly Species.PLoS Neglected Tropical Diseases2016
26784165Exploration of Scaffolds from Natural Products with Antiplasmodial Activities, Currently Registered Antimalarial Drugs and Public Malarial Screen Data.Molecules2016
27411306Identification of phenotype-relevant differentially expressed genes in breast cancer demonstrates enhanced quantile discretization protocol's utility in multi-platform microarray data integration.Journal of Bioinformatics and Computational Biology2016
27082250Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding.PLoS Genet2016
26823078Prioritization of anti-malarial hits from nature: chemo-informatic profiling of natural products with in vitro antiplasmodial activities and currently registered anti-malarial drugs.Malaria Journal2016
26856535Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis.BMC Bioinformatics2016
27935956Correction: Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding.PLoS Genet2016
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King Abdullah University of Science and Technology (KAUST)
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Harvard Medical School
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Computational Bioscience Research Center (CBRC)
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Post Graduate Institute of Medical Education and Research
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University of Cape Town
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Center for Omics Sciences, IRCCS San Raffaele Scientific Institute
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Massey University
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The Genome Institute of Singapore
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College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences
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Center for Integrative Medical Sciences
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Center for Computational Biology, Johns Hopkins University
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RIKEN Center for Integrative Medical Sciences
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University of British Columbia
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Institute of Infectious Disease and Molecular Medicine, University of Cape Town
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Johns Hopkins University
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Baylor College of Medicine
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Mater Research Institute-UQ, Translational Research Institute
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RIKEN Center for Integrative Medical Sciences
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International Centre for Genetic Engineering and Biotechnology
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