Author details

Full Name

Li Shen

Affiliation

ORCID

Career Start Year

2011

Papers

101

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37291337	Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury.		2023
36253194	CREB Binding at the Zfp189 Promoter Within Medium Spiny Neuron Subtypes Differentially Regulates Behavioral and Physiological Adaptations Over the Course of Cocaine Use.	Biological Psychiatry	2023
37781621	Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine.		2023
37620297	Circadian clock regulator Bmal1 gates axon regeneration via Tet3 epigenetics in mouse sensory neurons.		2023
37474762	Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain.		2023
37214877	Monomethylation of Lysine 27 at Histone 3 Confers Lifelong Susceptibility to Stress.		2023
36906500	Cell Type-Specific Whole-Genome Landscape of Î¿FOSB Binding in the Nucleus Accumbens After Chronic Cocaine Exposure.	Biol Psychiatry	2023
36711574	Transcriptional signatures of heroin intake and seeking throughout the brain reward circuit.		2023
37205414	Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior.		2023
37205394	ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.		2023
36763659	Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models.		2023
37451265	Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression.		2023
37294757	Transcriptional signatures of heroin intake and relapse throughout the brain reward circuitry in male mice.		2023
37503149	R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription.		2023
35086862	Macrophages facilitate peripheral nerve regeneration by organizing regeneration tracks through Plexin-B2.	Genes and Development	2022
36182529	Crystallin Mu in Medial Amygdala Mediates the Effect of Social Experience on Cocaine Seeking in Males but Not in Females.	Biological Psychiatry	2022
36178075	Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons.	Development (Cambridge)	2022
35459277	Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia.	Nat Commun	2022
35902629	Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression.	Molecular Psychiatry	2022
36289231	Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.	Nature Communications	2022
36256821	TGM2-mediated histone transglutamination is dictated by steric accessibility.	Proc Natl Acad Sci U S A	2022
36449610	The long noncoding RNA FEDORA is a cell type- and sex-specific regulator of depression.	Science advances	2022
34130857	Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits and Molecular Signatures.	Biol Psychiatry	2022
33896623	Sex-Specific Role for SLIT1 in Regulating Stress Susceptibility.	Biological Psychiatry	2022
33892914	Sex-Specific Transcriptional Changes in Response to Adolescent Social Stress in the Brain's Reward Circuitry.	Biol Psychiatry	2022
34895699	Prenatal Î¿-Tetrahydrocannabinol Exposure in Males Leads to Motivational Disturbances Related to Striatal Epigenetic Dysregulation.	Biological Psychiatry	2022
35013133	Whole blood transcriptional signatures associated with rapid antidepressant response to ketamine in patients with treatment resistant depression.	Translational Psychiatry	2022
34425966	Gene-Targeted, CREB-Mediated Induction of Î¿FosB Controls Distinct Downstream Transcriptional Patterns Within D1 and D2 Medium Spiny Neurons.	Biological Psychiatry	2021
33637528	Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity.	Sci Adv	2021
34099514	Sperm transcriptional state associated with paternal transmission of stress phenotypes.	Journal of Neuroscience	2021
33833436	Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons.	Nat Neurosci	2021
33723435	Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons.	Nat Neurosci	2021
33723076	Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm.	Proceedings of the National Academy of Sciences of the United States of America	2021
33762610	Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment.	Sci Rep	2021
33441743	Optimization of probiotic therapeutics using machine learning in an artificial human gastrointestinal tract.	Scientific Reports	2021
34248950	Chronic Stress-Induced Depression and Anxiety Priming Modulated by Gut-Brain-Axis Immunity.	Frontiers in Immunology	2021
34903713	Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions.	Nat Commun	2021
34716243	Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.	Journal of the American Society of Nephrology : JASN	2021
34650052	Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion.	Nature Communications	2021
32711952	Role of Long Noncoding RNA Gas5 in Cocaine Action.	Biological Psychiatry	2020
31956913	Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium.	Nucleic Acids Research	2020
32304628	Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression.	Neuron	2020
32273471	Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking.	Science	2020
31308097	RGS4 Maintains Chronic Pain Symptoms in Rodent Models.	Journal of Neuroscience	2019
31591195	Divergent roles of astrocytic versus neuronal EAAT2 deficiency on cognition and overlap with aging and Alzheimer's molecular signatures.	Proc Natl Acad Sci U S A	2019
31704941	Early life stress alters transcriptomic patterning across reward circuitry in male and female mice.	Nat Commun	2019
30552390	A novel role for E2F3b in regulating cocaine action in the prefrontal cortex.	Neuropsychopharmacology	2019
30283037	Adolescent exposure to Î¿<sup>9</sup>-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons.	Mol Psychiatry	2019
30867594	Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.	Nature	2019
31427770	Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex.	Nat Neurosci	2019