Author details

Full Name

Andrew E Jaffe

Affiliation

ORCID

Career Start Year

2009

Papers

135

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36729133	Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex.	Acta Neuropathol	2023
36369482	The basolateral amygdala to lateral septum circuit is critical for regulating social novelty in mice.		2023
36123423	Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.	Mol Psychiatry	2023
37573005	TCF4 Mutations Disrupt Synaptic Function Through Dysregulation of RIMBP2 in Patient-Derived Cortical Neurons.		2023
37790540	Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.	medRxiv	2023
37704947	BiocMAP: a Bioconductor-friendly, GPU-accelerated pipeline for bisulfite-sequencing data.		2023
36778465	Hypermetabolism in mice carrying a near complete human chromosome 21.	bioRxiv	2023
36587842	Dysregulated systemic metabolism in a Down syndrome mouse model.	Mol Metab	2023
36712024	TCF4 mutations disrupt synaptic function through dysregulation of RIMBP2 in patient-derived cortical neurons.		2023
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
36945630	Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.	medRxiv	2023
36698068	SUFI: an automated approach to spectral unmixing of fluorescent multiplex images captured in mouse and post-mortem human brain tissues.	BMC Neurosci	2023
37249575	Hypermetabolism in mice carrying a near-complete human chromosome 21.	Elife	2023
35017298	Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance.	Proc Natl Acad Sci U S A	2022
35395503	Epigenome-wide association analyses of active injection drug use.	Drug Alcohol Depend	2022
35969790	Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders.	Proc Natl Acad Sci U S A	2022
36162734	Dysfunction of mitochondria and GABAergic interneurons in the anterior cingulate cortex of individuals with schizophrenia.	Neurosci Res	2022
36319771	Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes.	Nat Neurosci	2022
36316086	SCRAP: a bioinformatic pipeline for the analysis of small chimeric RNA-seq data.	RNA	2022
36451089	CaPTure: Calcium PeakToolbox for analysis of in vitro calcium imaging data.	BMC Neuroscience	2022
36845993	Differential expression of <i>NPAS4</i> in the dorsolateral prefrontal cortex following opioid overdose.	Drug Alcohol Depend Rep	2022
35260864	Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways.	Nat Neurosci	2022
35236959	Molecular phenotypes associated with antipsychotic drugs in the human caudate nucleus.	Mol Psychiatry	2022
35236118	Genetics and Brain Transcriptomics of Completed Suicide.	Am J Psychiatry	2022
34969294	Curating the Evidence About COVID-19 for Frontline Public Health and Clinical Care: The Novel Coronavirus Research Compendium.	Public Health Rep	2022
35183789	Induction of Bdnf from promoter I following electroconvulsive seizures contributes to structural plasticity in neurons of the piriform cortex.	Brain Stimulation	2022
34582785	Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain.	Neuron	2021
32404946	Cortical cellular diversity and development in schizophrenia.	Molecular Psychiatry	2021
34294043	Correction to: SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductorâ¿¿powered RNAâ¿¿seq analyses.	BMC Bioinformatics	2021
33965196	Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity.	Biological Psychiatry	2021
33900848	Altered adipokines in obese adolescents: a cross-sectional and longitudinal analysis across the spectrum of glycemia.	Am J Physiol Endocrinol Metab	2021
33667780	Epigenome-wide study of brain DNA methylation following acute opioid intoxication.	Drug Alcohol Depend	2021
33932985	SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductor-powered RNA-seq analyses.	BMC Bioinformatics	2021
33558695	Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex.	Nat Neurosci	2021
33603232	Publisher Correction: Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex.	Nat Neurosci	2021
33649454	Single molecule in situ hybridization reveals distinct localizations of schizophrenia risk-related transcripts SNX19 and AS3MT in human brain.	Mol Psychiatry	2021
32632206	Older molecular brain age in severe mental illness.	Mol Psychiatry	2021
32602773	Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex.	Epigenetics	2021
34844637	recount3: summaries and queries for large-scale RNA-seq expression and splicing.	Genome Biol	2021
34429070	Cerebral cortex and blood transcriptome changes in mouse neonates prenatally exposed to air pollution particulate matter.	Journal of Neurodevelopmental Disorders	2021
34475392	Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk.	Nat Commun	2021
31444395	Spatial transcriptomics: putting genome-wide expression on the map.		2020
32433545	Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and schizophrenia.	Transl Psychiatry	2020
32203495	Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk.	Nat Neurosci	2020
32079618	Recounting the FANTOM CAGE-Associated Transcriptome.	Genome Res	2020
31852722	Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation.	Genome Res	2020
32015540	A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder.	Nat Neurosci	2020
31941661	TrkB Signaling Influences Gene Expression in Cortistatin-Expressing Interneurons.	eNeuro	2020
31570775	KCNH2-3.1 mediates aberrant complement activation and impaired hippocampal-medial prefrontal circuitry associated with working memory deficits.	Molecular Psychiatry	2020
32383753	dotdotdot: an automated approach to quantify multiplex single molecule fluorescent in situ hybridization (smFISH) images in complex tissues.	Nucleic Acids Research	2020