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Author Details

Courtney L Jones
Princess Margaret Cancer Centre, University Health Network
2014
28
18
PMIDPaper TitleJournal TitlePublished Year
37110126Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2.Metabolites2023
37525977Turning Down the Temperature on Leukemia Stem Cells.Cancer Res2023
37873284Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.bioRxiv2023
37021547Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity.Haematologica2023
34525179The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.Blood2022
35803545Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors.Exp Hematol2022
35668135The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.Nat Cell Biol2022
34027418SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA.Blood Cancer Discov2021
33667359Targeting Energy Metabolism in Cancer Stem Cells: Progress and Challenges in Leukemia and Solid Tumors.Cell Stem Cell2021
32841218ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes.JCI Insight2020
33884374Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells.Nat Cancer2020
31974170Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.Cancer Discov2020
33437968Enriching for human acute myeloid leukemia stem cells using reactive oxygen species-based cell sorting.STAR Protoc2020
32822582Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells.Cell Stem Cell2020
31048320The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells.Cancer Discov2019
31101624Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.Blood2019
30943405The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.Cell Rep2019
31142509IL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression.Cancer Res2019
30753831Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.Cancer Cell2019
30420752Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.Nat Med2018
30209285Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes.Nat Commun2018
30423294Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.Cancer Cell2018
27995737Splice site mutation in factor X gene manifesting as severe intracranial haemorrhage in neonatal period with a challenging treatment course.Haemophilia2017
26558807Genomic Characterization of Poorly Differentiated Neuroendocrine Carcinoma in a Pediatric Patient.J Pediatr Hematol Oncol2016
26324703MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.Blood2015
24942023The biology of relapsed acute lymphoblastic leukemia: opportunities for therapeutic interventions.J Pediatr Hematol Oncol2014
24895125Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model.J Biol Chem2014
24995804Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia.Br J Haematol2014
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Collaborators

Veronica Clavijo Jordan
Harvard Medical School
Co-authored papers 15
Brett M Stevens
University of Colorado School of Medicine
Co-authored papers 14
Angelo D'Alessandro
University of Colorado Anschutz Medical Campus
Co-authored papers 13
Shanshan Pei
Zhejiang University Medical Center
Co-authored papers 11
Daniel A Pollyea
University of Colorado Division of Hematology
Co-authored papers 11
Rachel Culp-Hill
University of Colorado Anschutz Medical Campus
Co-authored papers 9
Amanda Winters
University of Colorado School of Medicine
Co-authored papers 7
Haobin Ye
Institute of Metabolism & Integrative Biology, Fudan University
Co-authored papers 7
Anna Krug
University of Colorado School of Medicine
Co-authored papers 7
Julie A Reisz
University of Colorado Anschutz Medical Campus
Co-authored papers 7
Mohammad Minhajuddin
University of Colorado School of Medicine
Co-authored papers 7
Clayton A Smith
University of Colorado, Aurora CO.
Co-authored papers 6
Travis Nemkov
University of Colorado Anschutz Medical Campus
Co-authored papers 5
Maria Amaya
University of Colorado School of Medicine
Co-authored papers 4
Anagha Inguva
University of Colorado School of Medicine
Co-authored papers 4
James DeGregori
University of Colorado Anschutz Medical Campus
Co-authored papers 4
Biniam Adane
The Broad Institute of MIT and Harvard
Co-authored papers 4
Christopher C Porter
Emory University School of Medicine
Co-authored papers 4
Diana Abbott
Center for Innovative Design and Analysis, University of Colorado, Aurora CO.
Co-authored papers 4
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Michael W Becker
James P. Wilmot Cancer Institute, University of Rochester Medical Center Rochester
Co-authored papers 3
Fabia Gamboni
University of Colorado Anschutz Medical Campus
Co-authored papers 3
John E Dick
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Stephen P Hunger
Children's Hospital of Philadelphia
Co-authored papers 2
Mignon L Loh
University of Washington
Co-authored papers 1
James C Costello
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Michael W Deininger
University of Utah Huntsman Cancer Institute
Co-authored papers 1
Anca Franzini
University of Utah
Co-authored papers 1
Tamilla Nechiporuk
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Sarah Gehrke
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