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Author Details
Full Name
Joel S Bader
Affiliation
Johns Hopkins University
ORCID
Career Start Year
1993
Papers
132
H Index
50
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36604566
Triple negative breast tumors contain heterogeneous cancer cells expressing distinct KRAS-dependent collective and disseminative invasion programs.
Oncogene
2023
38020977
Parallel laboratory evolution and rational debugging reveal genomic plasticity to <i>S. cerevisiae</i> synthetic chromosome XIV defects.
Cell Genom
2023
38020971
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.
Cell Genom
2023
38020970
Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration.
Cell Genom
2023
38020968
Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast.
Cell Genom
2023
37944511
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions.
Cell
2023
37090629
Functional whole genome screen of nutrient-starved <i>Mycobacterium tuberculosis</i> identifies genes involved in antibiotic tolerance.
bioRxiv
2023
37061542
Next-generation large-scale binary protein interaction network for Drosophila melanogaster.
Nat Commun
2023
37339222
Pervasive RNA folding is crucial for narnavirus genome maintenance.
Proc Natl Acad Sci U S A
2023
37101120
Priors, population sizes, and power in genome-wide hypothesis tests.
BMC Bioinformatics
2023
36881486
Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion.
J Clin Invest
2023
33118835
Myocardial Gene Expression Signatures in Human Heart Failure With Preserved Ejection Fraction.
Circulation
2021
33683021
Schizophrenia risk alleles often affect the expression of many genes and each gene may have a different effect on the risk: A mediation analysis.
Am J Med Genet B Neuropsychiatr Genet
2021
33681435
Transcriptomic data of Clozapine-treated Ngn2-induced Human Excitatory Neurons.
Data Brief
2021
33497908
Transcriptome analysis of human induced excitatory neurons supports a strong effect of clozapine on cholesterol biosynthesis.
Schizophr Res
2021
34523947
Genetic Determinants of Intrinsic Antibiotic Tolerance in Mycobacterium avium.
Microbiol Spectr
2021
34003798
Protein synthesis inhibitor omacetaxine is effective against hepatocellular carcinoma.
JCI Insight
2021
33999839
The Panorama of Cancer Genetics.
Cancer Res
2021
32569517
Synthetic Genomes.
Annu Rev Biochem
2020
31961880
Between-tumor and within-tumor heterogeneity in invasive potential.
PLoS Comput Biol
2020
32042152
BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells.
Nat Struct Mol Biol
2020
31974396
Identifying the essential genes of Mycobacterium avium subsp. hominissuis with Tn-Seq using a rank-based filter procedure.
Sci Rep
2020
32091578
OrgDyn: feature- and model-based characterization of spatial and temporal organoid dynamics.
Bioinformatics
2020
33303586
Genetic interaction mapping informs integrative structure determination of protein complexes.
Science
2020
32645139
Cancer cells educate natural killer cells to a metastasis-promoting cell state.
J Cell Biol
2020
30674722
Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity.
JCI Insight
2019
31624201
Technological challenges and milestones for writing genomes.
Science
2019
31485072
E-cadherin is required for metastasis in multiple models of breast cancer.
Nature
2019
30906866
Inhibiting the stringent response blocks <i>Mycobacterium tuberculosis</i> entry into quiescence and reduces persistence.
Sci Adv
2019
29789590
Heterozygous diploid and interspecies SCRaMbLEing.
Nat Commun
2018
30046033
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.
Nat Commun
2018
30512015
Genome analysis of Mycobacterium avium subspecies hominissuis strain 109.
Sci Data
2018
29670589
Gene Enrichment Analysis Reveals Major Regulators of <i>Mycobacterium tuberculosis</i> Gene Expression in Two Models of Antibiotic Tolerance.
Front Microbiol
2018
29638227
A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors.
Nat Methods
2018
28073315
Metabolically Active Three-Dimensional Brown Adipose Tissue Engineered from White Adipose-Derived Stem Cells.
Tissue Eng Part A
2017
28280199
Design of a synthetic yeast genome.
Science
2017
28280153
Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.
Science
2017
28280154
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond.
Science
2017
28280152
Bug mapping and fitness testing of chemically synthesized chromosome X.
Science
2017
28280151
"Perfect" designer chromosome V and behavior of a ring derivative.
Science
2017
28280150
3D organization of synthetic and scrambled chromosomes.
Science
2017
28280149
Engineering the ribosomal DNA in a megabase synthetic chromosome.
Science
2017
28135421
Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosis.
Am J Respir Cell Mol Biol
2017
28174266
Low escape-rate genome safeguards with minimal molecular perturbation of <i>Saccharomyces cerevisiae</i>.
Proc Natl Acad Sci U S A
2017
26975995
Multiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization Predictions.
Infect Immun
2016
26568632
BioPartsBuilder: a synthetic biology tool for combinatorial assembly of biological parts.
Bioinformatics
2016
26566658
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.
Genome Res
2016
27684578
The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox.
Nat Methods
2016
27412090
BioPartsDB: a synthetic biology workflow web-application for education and research.
Bioinformatics
2016
26831077
Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters.
Proc Natl Acad Sci U S A
2016
1 - 50 of 132
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