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Author Details

Joel S Bader
Johns Hopkins University
1993
132
50
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36604566Triple negative breast tumors contain heterogeneous cancer cells expressing distinct KRAS-dependent collective and disseminative invasion programs.Oncogene2023
38020977Parallel laboratory evolution and rational debugging reveal genomic plasticity to <i>S. cerevisiae</i> synthetic chromosome XIV defects.Cell Genom2023
38020971Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.Cell Genom2023
38020970Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration.Cell Genom2023
38020968Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast.Cell Genom2023
37944511Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions.Cell2023
37090629Functional whole genome screen of nutrient-starved <i>Mycobacterium tuberculosis</i> identifies genes involved in antibiotic tolerance.bioRxiv2023
37061542Next-generation large-scale binary protein interaction network for Drosophila melanogaster.Nat Commun2023
37339222Pervasive RNA folding is crucial for narnavirus genome maintenance.Proc Natl Acad Sci U S A2023
37101120Priors, population sizes, and power in genome-wide hypothesis tests.BMC Bioinformatics2023
36881486Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion.J Clin Invest2023
33118835Myocardial Gene Expression Signatures in Human Heart Failure With Preserved Ejection Fraction.Circulation2021
33683021Schizophrenia risk alleles often affect the expression of many genes and each gene may have a different effect on the risk: A mediation analysis.Am J Med Genet B Neuropsychiatr Genet2021
33681435Transcriptomic data of Clozapine-treated Ngn2-induced Human Excitatory Neurons.Data Brief2021
33497908Transcriptome analysis of human induced excitatory neurons supports a strong effect of clozapine on cholesterol biosynthesis.Schizophr Res2021
34523947Genetic Determinants of Intrinsic Antibiotic Tolerance in Mycobacterium avium.Microbiol Spectr2021
34003798Protein synthesis inhibitor omacetaxine is effective against hepatocellular carcinoma.JCI Insight2021
33999839The Panorama of Cancer Genetics.Cancer Res2021
32569517Synthetic Genomes.Annu Rev Biochem2020
31961880Between-tumor and within-tumor heterogeneity in invasive potential.PLoS Comput Biol2020
32042152BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells.Nat Struct Mol Biol2020
31974396Identifying the essential genes of Mycobacterium avium subsp. hominissuis with Tn-Seq using a rank-based filter procedure.Sci Rep2020
32091578OrgDyn: feature- and model-based characterization of spatial and temporal organoid dynamics.Bioinformatics2020
33303586Genetic interaction mapping informs integrative structure determination of protein complexes.Science2020
32645139Cancer cells educate natural killer cells to a metastasis-promoting cell state.J Cell Biol2020
30674722Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity.JCI Insight2019
31624201Technological challenges and milestones for writing genomes.Science2019
31485072E-cadherin is required for metastasis in multiple models of breast cancer.Nature2019
30906866Inhibiting the stringent response blocks <i>Mycobacterium tuberculosis</i> entry into quiescence and reduces persistence.Sci Adv2019
29789590Heterozygous diploid and interspecies SCRaMbLEing.Nat Commun2018
30046033PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.Nat Commun2018
30512015Genome analysis of Mycobacterium avium subspecies hominissuis strain 109.Sci Data2018
29670589Gene Enrichment Analysis Reveals Major Regulators of <i>Mycobacterium tuberculosis</i> Gene Expression in Two Models of Antibiotic Tolerance.Front Microbiol2018
29638227A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors.Nat Methods2018
28073315Metabolically Active Three-Dimensional Brown Adipose Tissue Engineered from White Adipose-Derived Stem Cells.Tissue Eng Part A2017
28280199Design of a synthetic yeast genome.Science2017
28280153Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.Science2017
28280154Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond.Science2017
28280152Bug mapping and fitness testing of chemically synthesized chromosome X.Science2017
28280151"Perfect" designer chromosome V and behavior of a ring derivative.Science2017
282801503D organization of synthetic and scrambled chromosomes.Science2017
28280149Engineering the ribosomal DNA in a megabase synthetic chromosome.Science2017
28135421Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosis.Am J Respir Cell Mol Biol2017
28174266Low escape-rate genome safeguards with minimal molecular perturbation of <i>Saccharomyces cerevisiae</i>.Proc Natl Acad Sci U S A2017
26975995Multiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization Predictions.Infect Immun2016
26568632BioPartsBuilder: a synthetic biology tool for combinatorial assembly of biological parts.Bioinformatics2016
26566658SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.Genome Res2016
27684578The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox.Nat Methods2016
27412090BioPartsDB: a synthetic biology workflow web-application for education and research.Bioinformatics2016
26831077Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters.Proc Natl Acad Sci U S A2016
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Collaborators

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Co-authored papers 43
Co-authored papers 16
Massachusetts General Hospital
Co-authored papers 9
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Co-authored papers 9
Co-authored papers 8
Experimental Research Center, China Academy of Chinese Medical Sciences
Co-authored papers 7
Co-authored papers 6
Indiana University-Purdue University
Co-authored papers 5
Institute for Systems Genetics, NYU Grossman School of Medicine
Co-authored papers 4
Johns Hopkins University School of Medicine
Co-authored papers 4
the University of Hong Kong
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Institute of Medical Research, Northwestern Polytechnical University
Co-authored papers 3
College of Life Sciences and Oceanography, Shenzhen University
Co-authored papers 3
Rollins School of Public Health, Emory University
Co-authored papers 3
Johns Hopkins School of Medicine
Co-authored papers 3
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
German Research Center for Environmental Health
Co-authored papers 2
National Institute on Aging, National Institutes of Health
Co-authored papers 2
King's College London
Co-authored papers 2
Co-authored papers 2
California Pacific Medical Center, Research Institute
Co-authored papers 2
Co-authored papers 2
University of Michigan School of Public Health ann arbor
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2