Author details

Full Name

James J Chou

Affiliation

Harvard Medical School

ORCID

Career Start Year

1993

Papers

113

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36604598	Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation.	Cell Res	2023
37535730	Structural basis of Î³ chain family receptor sharing at the membrane level.	Science	2023
37205582	Structural basis of <i>Î³</i> -chain family receptor sharing at the membrane level.	bioRxiv	2023
36961368	Self-Assembled L-DNA Linkers for Rapid Construction of Multi-Specific Antibody-Drug Conjugates Library.	Angew Chem Int Ed Engl	2023
36686715	Editorial: Targeting TNF/TNFR signaling pathways.	Front Pharmacol	2023
34694903	Structure of the Streptococcus pyogenes NAD<sup>+</sup> Glycohydrolase Translocation Domain and Its Essential Role in Toxin Binding to Oropharyngeal Keratinocytes.	J Bacteriol	2022
35907884	Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance.	Nat Commun	2022
34086443	A Trimeric Hydrophobic Zipper Mediates the Intramembrane Assembly of SARS-CoV-2 Spike.	J Am Chem Soc	2021
33882664	NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology.	J Am Chem Soc	2021
33851163	A trimeric hydrophobic zipper mediates the intramembrane assembly of SARS-CoV-2 spike.	bioRxiv	2021
33802584	Inhibitor Development against p7 Channel in Hepatitis C Virus.	Molecules	2021
34101209	An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrialâ£membrane.	EMBO J	2021
32258880	Structural Characterization of the N-Terminal Domain of the <i>Dictyostelium discoideum</i> Mitochondrial Calcium Uniporter.	ACS Omega	2020
33163490	The Diversity and Similarity of Transmembrane Trimerization of TNF Receptors.	Front Cell Dev Biol	2020
32152540	HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.	Nat Chem Biol	2020
32385256	Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein.	Nat Commun	2020
30990942	Unidirectional Presentation of Membrane Proteins in Nanoparticle-Supported Liposomes.	Angew Chem Int Ed Engl	2019
31993277	DNA-Mediated Assembly of Multispecific Antibodies for T Cell Engaging and Tumor Killing.	Adv Sci (Weinh)	2019
31270510	Structure determination protocol for transmembrane domain oligomers.	Nat Protoc	2019
31468972	Critical Effect of the Detergent:Protein Ratio on the Formation of the Hepatitis C Virus p7 Channel.	Biochemistry	2019
30827683	Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.	Cell	2019
29551287	The Unusual Transmembrane Partition of the Hexameric Channel of the Hepatitis C Virus.	Structure	2018
30185554	Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.	Proc Natl Acad Sci U S A	2018
30177759	Reply to 'Concerns with yeast mitochondrial ADP/ATP carrier's integrity in DPC' and 'Dynamics and interactions of AAC3 in DPC are not functionally relevant'.	Nat Struct Mol Biol	2018
30333581	Chen et al. reply.	Nature	2018
29703750	Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain.	J Biol Chem	2018
27747952	Optimal Bicelle Size q for Solution NMR Studies of the Protein Transmembrane Partition.	Chemistry	2017
28325874	Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter.	Proc Natl Acad Sci U S A	2017
29234103	An Exhaustive Search Algorithm to Aid NMR-Based Structure Determination of Rotationally Symmetric Transmembrane Oligomers.	Sci Rep	2017
29193965	Stability and Water Accessibility of the Trimeric Membrane Anchors of the HIV-1 Envelope Spikes.	J Am Chem Soc	2017
28781081	Specific Interaction of the Human Mitochondrial Uncoupling Protein 1 with Free Long-Chain Fatty Acid.	Structure	2017
27873460	Sortase A-Generated Highly Potent Anti-CD20-MMAE Conjugates for Efficient Elimination of B-Lineage Lymphomas.	Small	2017
27868386	Structure of the transmembrane domain of HIV-1 envelope glycoprotein.	FEBS J	2017
26951497	Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride.	Protein Cell	2016
27625145	Specific Lipid Binding of Membrane Proteins in Detergent Micelles Characterized by NMR and Molecular Dynamics.	Biochemistry	2016
27135929	Architecture of the mitochondrial calcium uniporter.	Nature	2016
27338706	Structural basis for membrane anchoring of HIV-1 envelope spike.	Science	2016
26853147	Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.	Mol Cell	2016
26928605	A functional NMR for membrane proteins: dynamics, ligand binding, and allosteric modulation.	Protein Sci	2016
25605594	Mapping conformational heterogeneity of mitochondrial nucleotide transporter in uninhibited states.	Angew Chem Int Ed Engl	2015
26581523	Corrigendum: Structure and multistate function of the transmembrane electron transporter CcdA.	Nat Struct Mol Biol	2015
26389738	Structure and multistate function of the transmembrane electron transporter CcdA.	Nat Struct Mol Biol	2015
26218479	Structure and Mechanism of the Influenza A M218-60 Dimer of Dimers.	J Am Chem Soc	2015
26167881	Substrate-modulated ADP/ATP-transporter dynamics revealed by NMR relaxation dispersion.	Nat Struct Mol Biol	2015
26140997	Transmembrane signaling: A multiplex problem with converging solutions.	Prog Biophys Mol Biol	2015
26165595	Molecular Basis of MgATP Selectivity of the Mitochondrial SCaMC Carrier.	Structure	2015
25724842	Transverse relaxation dispersion of the p7 membrane channel from hepatitis C virus reveals conformational breathing.	J Biomol NMR	2015
25772504	Genotype-specific differences in structural features of hepatitis C virus (HCV) p7 membrane protein.	Biochim Biophys Acta	2015
24055819	The minimalist architectures of viroporins and their therapeutic implications.	Biochim Biophys Acta	2014
25127353	Fatty acid flippase activity of UCP2 is essential for its proton transport in mitochondria.	Cell Metab	2014

1 - 50 of 113

Innokentiy Maslennikov

School of Pharmacy , Chapman University

Career Start Year 2007

Number of shared co-authors 2

Tobias Madl

Gottfried Schatz Research Center, Medical University of Graz

Career Start Year 2005

Number of shared co-authors 5

Sebastian Hiller

University of Basel

Career Start Year 2003

Number of shared co-authors 6

Maofu Liao

Harvard Medical School

Career Start Year 2000

Number of shared co-authors 2

Georgios Skiniotis

Stanford University School of Medicine

Career Start Year 1999

Number of shared co-authors 0

Judith Klein-Seetharaman

School of Molecular Sciences & College of Health Solutions, Arizona State University

Career Start Year 1999

Number of shared co-authors 5

Philip T F Williamson

University of Southampton

Career Start Year 1997

Number of shared co-authors 5

Daniel Nietlispach

University of Cambridge

Career Start Year 1996

Number of shared co-authors 5

Witek Kwiatkowski

Swiss Federal Institute of Technology

Career Start Year 1996

Number of shared co-authors 3

Mark W Maciejewski

University of Connecticut School of Medicine

Career Start Year 1995

Number of shared co-authors 5

Volker D??tsch

Institute for Biophysical Chemistry, Goethe-University

Career Start Year 1995

Number of shared co-authors 2

Huan-Xiang Zhou

University of Illinois Chicago

Career Start Year 1993

Number of shared co-authors 1

Sonja A Dames

Technische Universitat Munchen

Career Start Year 1992

Number of shared co-authors 5

Michael Overduin

University of Alberta

Career Start Year 1992

Number of shared co-authors 5

Alexander P Golovanov

The University of Manchester

Career Start Year 1991

Number of shared co-authors 5

Michael Sattler

Technical University of Munich, Institute of Structural Biology

Career Start Year 1991

Number of shared co-authors 5

Julie D Forman-Kay

Hospital for Sick Children

Career Start Year 1989

Number of shared co-authors 6

Geerten W Vuister

Leicester Institute of Structural and Chemical Biology, University of Leicester

Career Start Year 1988

Number of shared co-authors 6

Paul C Driscoll

The Francis Crick Institute

Career Start Year 1987

Number of shared co-authors 5

Roland Riek

ETH Zurich

Career Start Year 1986

Number of shared co-authors 4

Stephan Grzesiek

University of Basel

Career Start Year 1986

Number of shared co-authors 5

Michael Nilges

Institut Pasteur

Career Start Year 1986

Number of shared co-authors 6

Lu-Yun Lian

Institute of Systems, The University of Liverpool

Career Start Year 1984

Number of shared co-authors 5

Toshimichi Fujiwara

Institute for Protein Research, Osaka University

Career Start Year 1983

Number of shared co-authors 5

William F DeGrado

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 1982

Number of shared co-authors 1

Angela M Gronenborn

University of Pittsburgh

Career Start Year 1980

Number of shared co-authors 7

Timothy A Cross

Florida State University

Career Start Year 1979

Number of shared co-authors 5

Marc Baldus

Bijvoet Center for Biomolecular Research, Utrecht University

Career Start Year 1976

Number of shared co-authors 5

David Cowburn

Albert Einstein College of Medicine

Career Start Year 1969

Number of shared co-authors 3

Kurt W??thrich

iHuman Institute, ShanghaiTech University

Career Start Year 1964

Number of shared co-authors 6

row(s) 1 - 30 of 30

Ad Bax

National Institutes of Health

Co-authored papers 8

Jason R Schnell

University of Oxford

Co-authored papers 8

Bing Chen

Co-authored papers 6

Michael S Seaman

Co-authored papers 4

Yongfei Cai

Co-authored papers 3

Tianshu Xiao

Co-authored papers 2

Michael C Wiener

University of Virginia

Co-authored papers 1

Piotr Sliz

The Manton Center for Orphan Disease Research, Boston Children's Hospital

Co-authored papers 1

David A Case

Rutgers University

Co-authored papers 1

Michael E Mendelsohn

Co-authored papers 1

Vamsi K Mootha

Broad Institute of MIT and Harvard

Co-authored papers 1

Michael G Malkowski

Jacobs School of Medicine and Biomedical Sciences, University of Buffalo

Co-authored papers 1

James M Carothers

Molecular Engineering & Sciences Institute, University of Washington

Co-authored papers 1

Tingjun Hou

Co-authored papers 1

Burkhard Rost

Technical University of Munich (TUM)

Co-authored papers 1

Raymond C Stevens

iHuman Institute, ShanghaiTech University

Co-authored papers 1

Stephen T C Wong

Houston Methodist Research Institute

Co-authored papers 1

David W Andrews

Sunnybrook Research Institute, University of Toronto

Co-authored papers 1

Wayne A Hendrickson

Columbia University

Co-authored papers 1

Michael H B Stowell

University of Colorado Boulder

Co-authored papers 1

Austin Huang

Alabama College of Osteopathic Medicine

Co-authored papers 1

Charles D Schwieters

National Institute of Diabetes and Digestive and Kidney Diseases

Co-authored papers 1

Douglas C Rees

Howard Hughes Medical Institute, California Institute of Technology

Co-authored papers 1

Hartmut Oschkinat

Leibniz-Forschungsinstitut fur Molekulare Pharmakologie

Co-authored papers 1

Shobha Potluri

Co-authored papers 1

John M Louis

National Institute of Diabetes and Digestive and Kidney Diseases

Co-authored papers 1

Avner Schlessinger

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Co-authored papers 1

Geoffrey Chang

Skaggs School of Pharmacy and Pharmaceutical Sciences.

Co-authored papers 1

Mark E Dumont

University of Rochester Medical Center

Co-authored papers 1

Robert M Stroud

University of California San Francisco

Co-authored papers 1

1 - 30

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