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Author Details

Shadmehr Demehri
Massachusetts General Hospital and Harvard Medical School
2004
77
24
PMIDPaper TitleJournal TitlePublished Year
36702949Combined PD-1, BRAF and MEK inhibition in BRAF<sup>V600E</sup> colorectal cancer: a phase 2 trial.Nat Med2023
37843274Carcinogen exposure enhances cancer immunogenicity by blocking the development of an immunosuppressive tumor microenvironment.J Clin Invest2023
37842153Cutaneous angiosarcoma of the scalp in a pediatric patient with xeroderma pigmentosum.JAAD Case Rep2023
37611292Treatment of an Unresectable Cutaneous Squamous Cell Carcinoma With ED&amp;C and 5-FU.Cutis2023
37734530Skin cancer prevention - Recent advances and unmet challenges.Cancer Lett2023
37731472Topical Calcipotriol Plus Imiquimod Immunotherapy for Nonkeratinocyte Skin Cancers.JID Innov2023
37001502Cytotoxic CD4<sup>+</sup> T cells eliminate senescent cells by targeting cytomegalovirus antigen.Cell2023
37427591TSLP/dendritic cell axis promotes CD4+ T cell tolerance to the gut microbiome.JCI Insight2023
36542363Prevention of Skin Cancers With Topical Calcipotriol and Fluorouracil in Patients With Xeroderma Pigmentosum.JAMA Dermatol2023
36711758Cutaneous immune-related adverse events are associated with longer overall survival in advanced cancer patients on immune checkpoint inhibitors: a multi-institutional cohort study.medRxiv2023
36711701Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression.Res Sq2023
36736626Cutaneous immune-related adverse events are associated with longer overall survival in advanced cancer patients on immune checkpoint inhibitors: A multi-institutional cohort study.J Am Acad Dermatol2023
36708946Nuclear IL-33 in Fibroblasts Promotes Skin Fibrosis.J Invest Dermatol2023
36733396Natural killer cells suppress cancer metastasis by eliminating circulating cancer cells.Front Immunol2023
35294229Extracellular matrix proteins regulate NK cell function in peripheral tissues.Sci Adv2022
35341735IL-33/Regulatory T-Cell Axis Suppresses Skin Fibrosis.J Invest Dermatol2022
35432341Alarmin Cytokines as Central Regulators of Cutaneous Immunity.Front Immunol2022
35527181The extracellular matrix and immunity: breaking the old barrier in cancer.Trends Immunol2022
35565302Thymic Stromal Lymphopoietin Induction Suppresses Lung Cancer Development.Cancers (Basel)2022
35561684Topical therapy for regression and melanoma prevention of congenital giant nevi.Cell2022
35657353CD4+ T helper 2 cells suppress breast cancer by inducing terminal differentiation.J Exp Med2022
36714811Compromised T Cell Immunity Links Increased Cutaneous Papillomavirus Activity to Squamous Cell Carcinoma Risk.JID Innov2022
36467403Thymic stromal lymphopoietin-stimulated CD4<sup>+</sup> T cells induce senescence in advanced breast cancer.Front Cell Dev Biol2022
36174410Extracellular matrix-natural killer cell interactome: an uncharted territory in health and disease.Curr Opin Immunol2022
35867136Lethal Dermal Sarcoma in Immunosuppressed Patients.Oncologist2022
36199787Trending Anti-E7 Serology Predicts Mortality and Recurrence of HPV-Associated Cancers of the Oropharynx.J Oncol2022
35131083STK11 Loss: A Novel Mechanism for Melanoma Metastasis with Therapeutic Implications.J Invest Dermatol2022
35073167Cutaneous Squamous Cell Carcinoma: The Frontier of Cancer Immunoprevention.Annu Rev Pathol2022
35310879Topical Calcipotriol Plus 5-Fluorouracil Immunotherapy for Actinic Keratosis Treatment.JID Innov2022
34162549Rejection of benign melanocytic nevi by nevus-resident CD4<sup>+</sup> T cells.Sci Adv2021
33842408Meeting Report: Translational Advances in Cancer Prevention Agent Development Meeting.J Cancer Prev2021
33616251Nuclear IL-33/SMAD signaling axis promotes cancer development in chronic inflammation.EMBO J2021
34544686Supporting the Next Generation of Scientists to Lead Cancer Immunology Research.Cancer Immunol Res2021
34560914Innate Lymphoid Cells: New Targets for Cutaneous Squamous Cell Carcinoma Immunotherapy.J Invest Dermatol2021
34144976CD8<sup>+</sup> T cell immunity blocks the metastasis of carcinogen-exposed breast cancer.Sci Adv2021
32232031A Case of Nivolumab-Induced Cutaneous Toxicity with Multiple Morphologies.Dermatopathology (Basel)2020
32073194Hypertrophic Lichen Planus with Histological Features of Squamous Cell Carcinoma Associated with Immune Checkpoint Blockade Therapy.Oncologist2020
32068037Enhancing the process for care delivery in a dermatology specialty clinic.J Am Acad Dermatol2020
31881212Reduction in Human Epidermal Langerhans Cells with Age Is Associated with Decline in CXCL14-Mediated Recruitment of CD14<sup>+</sup> Monocytes.J Invest Dermatol2020
33007298Human papillomavirus-positivity is associated with EREG down-regulation and promoter hypermethylation in head and neck squamous cell carcinoma.Exp Mol Pathol2020
32554617Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer.J Immunother Cancer2020
32147504Divergent Roles of Epithelium-Derived Alarmins in Notch Signaling-Deficient Skin.J Invest Dermatol2020
30696763IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation.Proc Natl Acad Sci U S A2019
31666702Immunity to commensal papillomaviruses protects against skin cancer.Nature2019
30030152Chronic Inflammation Promotes Skin Carcinogenesis in Cancer-Prone Discoid Lupus Erythematosus.J Invest Dermatol2019
31332324CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity.Nat Biotechnol2019
31102460Immunotherapeutic strategies for cutaneous squamous cell carcinoma prevention in xeroderma pigmentosum.Br J Dermatol2019
30869654Chimeric antigen receptor costimulation domains modulate human regulatory T cell function.JCI Insight2019
30895944Skin cancer precursor immunotherapy for squamous cell carcinoma prevention.JCI Insight2019
30785593Topical Combination of Fluorouracil and Calcipotriene as a Palliative Therapy for Refractory Extramammary Paget Disease.JAMA Dermatol2019
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Collaborators

Brian J Druker
Oregon Health & Science University
Co-authored papers 7
Michael W Deininger
University of Utah Huntsman Cancer Institute
Co-authored papers 7
Alice S Whittemore
Co-authored papers 2
Thoralf Lange
Hospital Weissenfels
Co-authored papers 2
Eduardo Vilar
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Wayne M Yokoyama
Co-authored papers 2
Michael J Holtzman
Co-authored papers 2
Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 2
Brian V Nahed
Harvard Medical School
Co-authored papers 1
Lawrence Fong
University of California san francisco
Co-authored papers 1
Julian M Hess
Broad Institute of MIT and Harvard
Co-authored papers 1
Jianmin Wang
Roswell Park Comprehensive Cancer Center
Co-authored papers 1
Angela M Christiano
Co-authored papers 1
Clifford A Meyer
Co-authored papers 1
Kun-Hsing Yu
Harvard Medical School
Co-authored papers 1
Eric Jorgenson
Co-authored papers 1
Steven Y He
Macquarie University
Co-authored papers 1
Norman E Sharpless
National Cancer Institute
Co-authored papers 1
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
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Sandra Otto
Co-authored papers 1
Lucy C Crossman
Oregon Health & Science University Cancer Institute
Co-authored papers 1
Mitsuru Morimoto
RIKEN Center for Biosystems Dynamics Research
Co-authored papers 1
Andrew T Chan
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1
Bob S Carter
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1
Dietger Niederwieser
University of Leipzig
Co-authored papers 1
Powel H Brown
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Marc M Loriaux
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Lucio Miele
Louisiana State University Health Sciences Center
Co-authored papers 1
James E Gern
University of Wisconsin School of Medicine and Public Health
Co-authored papers 1
Release 1.2