Author details

Full Name

Christopher J Roberts

Affiliation

School of Pharmacy, University of Nottingham

ORCID

Career Start Year

1989

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35386201	PIP5K1Î± is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer.	Front Cell Dev Biol	2022
33034050	Thyroid and androgen receptor signaling are antagonized by Î¼-Crystallin in prostate cancer.	Int J Cancer	2021
22445337	Transcriptional architecture of the primate neocortex.	Neuron	2012
18507503	Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.	PLoS Biol	2008
17719200	Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia.	Genomics	2007
16611858	Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers.	Drug Metab Dispos	2006
17503381	Development of an approach for ab initio estimation of compound-induced liver injury based on global gene transcriptional profiles.	Genome Inform	2006
17041087	Developing gene expression signatures of pathway deregulation in tumors.	Mol Cancer Ther	2006
17118916	Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition.	Xenobiotica	2006
17118914	Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.	Xenobiotica	2006
14718172	Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes.	Cell	2004
15242642	Exploration of essential gene functions via titratable promoter alleles.	Cell	2004
12735110	Development of a DNA microarray for toxicology based on hepatotoxin-regulated sequences.	EHP Toxicogenomics	2003
12140549	Functional profiling of the Saccharomyces cerevisiae genome.	Nature	2002
11160377	A novel gene conserved from yeast to humans is involved in sterol biosynthesis.	J Lipid Res	2001
11728304	Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins.	Curr Biol	2001
11390663	Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast.	Mol Cell Biol	2001
10657304	Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles.	Science	2000
10861905	Mutational analysis of the karmellae-inducing signal in Hmg1p, a yeast HMG-CoA reductase isozyme.	Yeast	2000
10888885	Widespread aneuploidy revealed by DNA microarray expression profiling.	Nat Genet	2000
10929718	Functional discovery via a compendium of expression profiles.	Cell	2000
10667584	Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae.	Cancer Res	2000
10512876	The role of the 3-hydroxy 3-methylglutaryl coenzyme A reductase cytosolic domain in karmellae biogenesis.	Mol Biol Cell	1999
10436161	Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.	Science	1999
10417390	Genetic selection of peptide inhibitors of biological pathways.	Science	1999
9809554	Drug target validation and identification of secondary drug target effects using DNA microarrays.	Nat Med	1998
9427750	Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints.	EMBO J	1998
9738881	Mutations in the dim-1 gene of Neurospora crassa reduce the level of DNA methylation.	Mol Gen Genet	1998
9353181	Integrating genetic approaches into the discovery of anticancer drugs.	Science	1997
9171090	Expression of herpes virus thymidine kinase in Neurospora crassa.	Nucleic Acids Res	1997
8744950	Different subcellular localization of Saccharomyces cerevisiae HMG-CoA reductase isozymes at elevated levels corresponds to distinct endoplasmic reticulum membrane proliferations.	Mol Biol Cell	1996
7824923	Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.	Science	1995
8532524	Mutations affecting the biosynthesis of S-adenosylmethionine cause reduction of DNA methylation in Neurospora crassa.	Nucleic Acids Res	1995
7505062	Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.	Science	1993
8509444	Membrane protein retention in the yeast Golgi apparatus: dipeptidyl aminopeptidase A is retained by a cytoplasmic signal containing aromatic residues.	J Cell Biol	1993
1428679	Biogenesis of the vacuole in Saccharomyces cerevisiae.	Int Rev Cytol	1992
1527174	Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment.	J Cell Biol	1992
1706462	Methods for studying the yeast vacuole.	Methods Enzymol	1991
2647766	Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole.	J Cell Biol	1989

1 - 39 of 39

Yunchen Gong

University of Toronto

Career Start Year 2000

Number of shared co-authors 2

Allyson F O'Donnell

University of Pittsburgh

Career Start Year 2000

Number of shared co-authors 1

Michael Davey

BC Children's Hospital Research Institute, University of British Columbia

Career Start Year 2000

Number of shared co-authors 6

Maya Schuldiner

The Weizmann Institute of Science

Career Start Year 2000

Number of shared co-authors 5

Amy Hin Yan Tong

University of Toronto

Career Start Year 1999

Number of shared co-authors 16

Pablo S Aguilar

Instituto de Fisiologia

Career Start Year 1998

Number of shared co-authors 1

Ashkan Golshani

Ottawa Institute of Systems Biology, Carleton University

Career Start Year 1997

Number of shared co-authors 5

Hyeseung Lee

Picower Institute for Learning and Memory, Massachusetts Institute of Technology

Career Start Year 1996

Number of shared co-authors 0

Chandra L Theesfeld

Lewis-Sigler Institute for Integrative Genomics, Princeton University

Career Start Year 1996

Number of shared co-authors 4

Tsuyoshi Miyake

University of Virginia School of Medicine

Career Start Year 1995

Number of shared co-authors 1

Marcello Marelli

AstraZeneca Oncology R&D

Career Start Year 1995

Number of shared co-authors 0

Kristin Baetz

Ottawa Institute of Systems Biology, University of Ottawa, University of Calgary

Career Start Year 1994

Number of shared co-authors 9

Kara Dolinski

Lewis-Sigler Institute for Integrative Genomics, Princeton University

Career Start Year 1994

Number of shared co-authors 4

Aim??e M Dudley

Pacific Northwest Research Institute

Career Start Year 1994

Number of shared co-authors 2

Won-Ki Huh

Seoul National University

Career Start Year 1991

Number of shared co-authors 2

J??rg B??hler

University College London

Career Start Year 1991

Number of shared co-authors 3

Marinella Gebbia

University of Toronto

Career Start Year 1989

Number of shared co-authors 12

John D Aitchison

Center for Global Infectious Disease Research, Seattle Children's Research Institute

Career Start Year 1988

Number of shared co-authors 2

Kwang-Lae Hoe

Chungnam National University

Career Start Year 1987

Number of shared co-authors 4

Hiten D Madhani

University of California san francisco

Career Start Year 1986

Number of shared co-authors 4

Yolanda Sanchez

Collegeville

Career Start Year 1985

Number of shared co-authors 0

Helena Friesen

University of Toronto

Career Start Year 1984

Number of shared co-authors 12

Michael Shales

University of California, USA Quantitative Biosciences Institute (QBI) san francisco

Career Start Year 1980

Number of shared co-authors 9

Richard A Rachubinski

University of Alberta

Career Start Year 1980

Number of shared co-authors 3

Pamela A Silver

Harvard Medical School

Career Start Year 1979

Number of shared co-authors 4

Jasper Rine

University of California berkeley

Career Start Year 1977

Number of shared co-authors 14

Stephen G Oliver

University of Cambridge

Career Start Year 1976

Number of shared co-authors 9

Suresh Subramani

University of California San Diego

Career Start Year 1975

Number of shared co-authors 0

Philip Hieter

University of British Columbia

Career Start Year 1974

Number of shared co-authors 15

David Botstein

Calico Life Sciences LLC

Career Start Year 1968

Number of shared co-authors 12

row(s) 1 - 30 of 30

Stephen H Friend

University of Oxford

Co-authored papers 9

Timothy R Hughes

University of Toronto

Co-authored papers 6

Charles Boone

University of Toronto

Co-authored papers 3

Patrice Menard

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark

Co-authored papers 2

Howard Bussey

McGill University

Co-authored papers 2

Elizabeth A Winzeler

University of California San Diego

Co-authored papers 2

Ronald W Davis

Stanford University

Co-authored papers 2

Mark Johnston

University of Colorado School of Medicine

Co-authored papers 2

Michael Snyder

Stanford University

Co-authored papers 2

Jef D Boeke

Institute for Systems Genetics, NYU School of Medicine

Co-authored papers 2

Jennifer Haynes

Joan C. Edwards School of Medicine, Marshall University

Co-authored papers 1

Joseph L DeRisi

University of California San Francisco

Co-authored papers 1

Andrey Loboda

Merck & Co., Inc.

Co-authored papers 1

Wen-Tao Peng

West China Second University Hospital, Sichuan University

Co-authored papers 1

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 1

Adam P Arkin

Lawrence Berkeley National Laboratory

Co-authored papers 1

Michael Hawrylycz

Allen Institute for Brain Science

Co-authored papers 1

John W Phillips

University of California los angeles

Co-authored papers 1

Andres Lopez

Universidad de Valparaiso

Co-authored papers 1

Shadmehr Demehri

Massachusetts General Hospital and Harvard Medical School

Co-authored papers 1

Thea Norman

Bill & Melinda Gates Foundation

Co-authored papers 1

Adam M Deutschbauer

Lawrence Berkeley National Laboratory

Co-authored papers 1

Deanna Gotte

Co-authored papers 1

Shawna L Hiley

University of Toronto College Street

Co-authored papers 1

Alexei A Podtelezhnikov

Genetics and Pharmacogenomics, Merck & Co., Inc.

Co-authored papers 1

Miles Trochesset

Co-authored papers 1

Sanie Mnaimneh

University of Toronto

Co-authored papers 1

Li Ni

College of Life Science, Shaanxi Normal University

Co-authored papers 1

Brenda J Andrews

University of Toronto

Co-authored papers 1

Daniel H Geschwind

University of California los angeles

Co-authored papers 1

1 - 30

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