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Author Details

Shelley L Berger
Penn Epigenetics Institute, Perelman School of Medicine
1985
242
97
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36638792Loss of epigenetic information as a cause of mammalian aging.Cell2023
37961560CTCF/cohesin organize the ground state of chromatin-nuclear speckle association.bioRxiv2023
37581481Neuromodulators and neuroepigenetics of social behavior in ants.Ann N Y Acad Sci2023
38091951Stat5 opposes the transcription factor Tox and rewires exhausted CD8<sup>+</sup> T cells toward durable effector-like states during chronic antigen exposure.Immunity2023
37257919Long ant life span is maintained by a unique heat shock factor.Genes Dev2023
37315535The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8<sup>+</sup> T cells.Immunity2023
37117791Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue aging.Nat Aging2023
37011008Type I Interferon Signaling via the EGR2 Transcriptional Regulator Potentiates CAR T Cell-Intrinsic Dysfunction.Cancer Discov2023
37467321TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells.Sci Adv2023
37292952Dynamic enhancer interactome promotes senescence and aging.bioRxiv2023
37224816Tissue-resident memory CAR T cells with stem-like characteristics display enhanced efficacy against solid and liquid tumors.Cell Rep Med2023
37061967Terri Grodzicker: advocate and influencer of impactful science.Genes Dev2023
36624294Publisher Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.Nature2023
36747034Author Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.Nature2023
36840361Ensheathing glia promote increased lifespan and healthy brain aging.Aging Cell2023
35061542Enzymatic transfer of acetate on histones from lysine reservoir sites to lysine activating sites.Sci Adv2022
35477756β-Hydroxybutyrate suppresses colorectal cancer.Nature2022
35851616ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16<sup>INK4a</sup> levels.Nat Cell Biol2022
36198800SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.Nature2022
36350986BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.Sci Transl Med2022
36193052Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia.iScience2022
35921439Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation.Proc Natl Acad Sci U S A2022
35320348Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer.Cancer Discov2022
35182476EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells.Mol Cell2022
33292048SIRT1 - a new mammalian substrate of nuclear autophagy.Autophagy2021
33823140p53 mediates target gene association with nuclear speckles for amplified RNA expression.Mol Cell2021
33705698RNA modification to the rescue!Cell Host Microbe2021
33636129In vivo CD8<sup>+</sup> T cell CRISPR screening reveals control by Fli1 in infection and cancer.Cell2021
34861191An NK-like CAR T cell transition in CAR T cell dysfunction.Cell2021
34550980Tramtrack acts during late pupal development to direct ant caste identity.PLoS Genet2021
34739833Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones.Cell2021
34358447ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.Mol Cell2021
33338653The biochemical and genetic discovery of the SAGA complex.Biochim Biophys Acta Gene Regul Mech2021
32553177Genetics Meets Epigenetics in Treg Cells and Autoimmunity.Immunity2020
32001516Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction.Cancer Discov2020
32001510Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence.Genes Dev2020
31732456Epigenetic Regulator CoREST Controls Social Behavior in Ants.Mol Cell2020
33033384Author Correction: An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease.Nat Genet2020
33154125Food for thought.Science2020
32933557Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark.Epigenetics Chromatin2020
32989324An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease.Nat Genet2020
32989246SIRT1 is downregulated by autophagy in senescence and ageing.Nat Cell Biol2020
32875108Social reprogramming in ants induces longevity-associated glia remodeling.Sci Adv2020
30397898Histone modification signatures in human sperm distinguish clinical abnormalities.J Assist Reprod Genet2019
31761669Gcn5-Mediated Histone Acetylation Governs Nucleosome Dynamics in Spermiogenesis.Dev Cell2019
31207603TOX transcriptionally and epigenetically programs CD8[+] T cell exhaustion.Nature2019
31606264TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.Immunity2019
30966857Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks.Cell Cycle2019
31049400p63 establishes epithelial enhancers at critical craniofacial development genes.Sci Adv2019
29091290Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform.Hepatology2018
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Collaborators

Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania
Co-authored papers 26
University of Pennsylvania
Co-authored papers 20
HHMI/NYU Langone School of Medicine
Co-authored papers 17
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 16
Arizona State University
Co-authored papers 16
The Rockefeller University
Co-authored papers 13
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 13
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 12
The Wistar Institute
Co-authored papers 7
Collegeville
Co-authored papers 7
Northwestern University Feinberg School of Medicine
Co-authored papers 7
1250 S. Collegeville Rd., Collegeville
Co-authored papers 6
Bogazici University
Co-authored papers 6
Epigenetics Institute, University of Pennsylvania
Co-authored papers 5
Co-authored papers 5
University of Pennsylvania
Co-authored papers 5
University of California San Diego
Co-authored papers 5
University of California San Francisco
Co-authored papers 4
University of New Mexico Health Sciences Center
Co-authored papers 4
Co-authored papers 4
Co-authored papers 4
University of Oxford
Co-authored papers 4
Beatson Institute for Cancer Research and the University of Glasgow
Co-authored papers 3
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 3
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Lewis Katz School of Medicine, Temple University
Co-authored papers 3
University of Pennsylvania Department of Pathology & Laboratory Medicine
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New York University
Co-authored papers 3
The Beatson Institute
Co-authored papers 3