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Author Details
Full Name
Shelley L Berger
Affiliation
Penn Epigenetics Institute, Perelman School of Medicine
ORCID
Career Start Year
1985
Papers
242
H Index
97
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36638792
Loss of epigenetic information as a cause of mammalian aging.
Cell
2023
37961560
CTCF/cohesin organize the ground state of chromatin-nuclear speckle association.
bioRxiv
2023
37581481
Neuromodulators and neuroepigenetics of social behavior in ants.
Ann N Y Acad Sci
2023
38091951
Stat5 opposes the transcription factor Tox and rewires exhausted CD8<sup>+</sup> TÂ cells toward durable effector-like states during chronic antigen exposure.
Immunity
2023
37257919
Long ant life span is maintained by a unique heat shock factor.
Genes Dev
2023
37315535
The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8<sup>+</sup> TÂ cells.
Immunity
2023
37117791
Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue aging.
Nat Aging
2023
37011008
Type I Interferon Signaling via the EGR2 Transcriptional Regulator Potentiates CAR T Cell-Intrinsic Dysfunction.
Cancer Discov
2023
37467321
TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells.
Sci Adv
2023
37292952
Dynamic enhancer interactome promotes senescence and aging.
bioRxiv
2023
37224816
Tissue-resident memory CAR TÂ cells with stem-like characteristics display enhanced efficacy against solid and liquid tumors.
Cell Rep Med
2023
37061967
Terri Grodzicker: advocate and influencer of impactful science.
Genes Dev
2023
36624294
Publisher Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.
Nature
2023
36747034
Author Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.
Nature
2023
36840361
Ensheathing glia promote increased lifespan and healthy brain aging.
Aging Cell
2023
35061542
Enzymatic transfer of acetate on histones from lysine reservoir sites to lysine activating sites.
Sci Adv
2022
35477756
β-Hydroxybutyrate suppresses colorectal cancer.
Nature
2022
35851616
ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16<sup>INK4a</sup> levels.
Nat Cell Biol
2022
36198800
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.
Nature
2022
36350986
BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.
Sci Transl Med
2022
36193052
Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia.
iScience
2022
35921439
Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation.
Proc Natl Acad Sci U S A
2022
35320348
Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer.
Cancer Discov
2022
35182476
EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells.
Mol Cell
2022
33292048
SIRT1 - a new mammalian substrate of nuclear autophagy.
Autophagy
2021
33823140
p53 mediates target gene association with nuclear speckles for amplified RNA expression.
Mol Cell
2021
33705698
RNA modification to the rescue!
Cell Host Microbe
2021
33636129
In vivo CD8<sup>+</sup> T cell CRISPR screening reveals control by Fli1 in infection and cancer.
Cell
2021
34861191
An NK-like CAR TÂ cell transition in CAR TÂ cell dysfunction.
Cell
2021
34550980
Tramtrack acts during late pupal development to direct ant caste identity.
PLoS Genet
2021
34739833
Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones.
Cell
2021
34358447
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.
Mol Cell
2021
33338653
The biochemical and genetic discovery of the SAGA complex.
Biochim Biophys Acta Gene Regul Mech
2021
32553177
Genetics Meets Epigenetics in Treg Cells and Autoimmunity.
Immunity
2020
32001516
Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction.
Cancer Discov
2020
32001510
Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence.
Genes Dev
2020
31732456
Epigenetic Regulator CoREST Controls Social Behavior in Ants.
Mol Cell
2020
33033384
Author Correction: An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease.
Nat Genet
2020
33154125
Food for thought.
Science
2020
32933557
Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark.
Epigenetics Chromatin
2020
32989324
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease.
Nat Genet
2020
32989246
SIRT1 is downregulated by autophagy in senescence and ageing.
Nat Cell Biol
2020
32875108
Social reprogramming in ants induces longevity-associated glia remodeling.
Sci Adv
2020
30397898
Histone modification signatures in human sperm distinguish clinical abnormalities.
J Assist Reprod Genet
2019
31761669
Gcn5-Mediated Histone Acetylation Governs Nucleosome Dynamics in Spermiogenesis.
Dev Cell
2019
31207603
TOX transcriptionally and epigenetically programs CD8[+] T cell exhaustion.
Nature
2019
31606264
TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8Â T Cell-Fate Decision.
Immunity
2019
30966857
Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks.
Cell Cycle
2019
31049400
p63 establishes epithelial enhancers at critical craniofacial development genes.
Sci Adv
2019
29091290
Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform.
Hepatology
2018
1 - 50 of 242
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Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania
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University of Pennsylvania
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Danny Reinberg
HHMI/NYU Langone School of Medicine
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Arizona State University
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C David Allis
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Peter D Adams
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Co-authored papers
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Karl M Glastad
Perelman School of Medicine, University of Pennsylvania
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12
Karl W Henry
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Co-authored papers
7
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Collegeville
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7
Ali Shilatifard
Northwestern University Feinberg School of Medicine
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Daniel F Simola
1250 S. Collegeville Rd., Collegeville
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6
Neset Cevdet Tolga Emre
Bogazici University
Co-authored papers
6
Kristin Ingvarsdottir
Epigenetics Institute, University of Pennsylvania
Co-authored papers
5
Li-San Wang
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5
John Q Trojanowski
University of Pennsylvania
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5
Lorraine Pillus
University of California San Diego
Co-authored papers
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