Author details

Full Name

Celine Lefebvre

Affiliation

The Scripps Research Institute

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37014043	Editor's Note: Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model.	Cancer Res	2023
35458399	Escalated (Dependent) Oxycodone Self-Administration Is Associated with Cognitive Impairment and Transcriptional Evidence of Neurodegeneration in Human Immunodeficiency Virus (HIV) Transgenic Rats.	Viruses	2022
34108514	Central nervous system (CNS) transcriptomic correlates of human immunodeficiency virus (HIV) brain RNA load in HIV-infected individuals.	Sci Rep	2021
31605699	Increases in compulsivity, inflammation, and neural injury in HIV transgenic rats with escalated methamphetamine self-administration under extended-access conditions.	Brain Res	2020
31412010	An Accessible and Unique Insight into Metastasis Mutational Content Through Whole-exome Sequencing of Circulating Tumor Cells in Metastatic Prostate Cancer.	Eur Urol Oncol	2020
29403038	Tumour spheres with inverted polarity drive the formation of peritoneal metastases in patients with hypermethylated colorectal carcinomas.	Nat Cell Biol	2018
30119077	Added Value of Whole-Exome and Transcriptome Sequencing for Clinical Molecular Screenings of Advanced Cancer Patients With Solid Tumors.	Cancer J	2018
28445538	Gene expression patterns associated with neurological disease in human HIV infection.	PLoS One	2017
28292442	ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.	Cancer Cell	2017
26758560	Circulating Cell-Free Tumor DNA Analysis of 50 Genes by Next-Generation Sequencing in the Prospective MOSCATO Trial.	Clin Cancer Res	2016
28027327	Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis.	PLoS Med	2016
27535334	Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations.	Cancer Res	2016
27390348	Mutational Landscape and Sensitivity to Immune Checkpoint Blockers.	Clin Cancer Res	2016
26708336	rCGH: a comprehensive array-based genomic profile platform for precision medicine.	Bioinformatics	2016
26907767	Whole exome sequencing of rare aggressive breast cancer histologies.	Breast Cancer Res Treat	2016
26825230	Translational regulation of the mRNA encoding the ubiquitin peptidase USP1 involved in the DNA damage response as a determinant of Cisplatin resistance.	Cell Cycle	2016
25336442	Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency.	Stem Cells	2015
26516201	Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1.	Science	2015
26429708	TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen.	BMC Med Genomics	2015
26196250	Precision medicine for metastatic breast cancer--limitations and solutions.	Nat Rev Clin Oncol	2015
26110827	ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs.	PLoS One	2015
26058079	Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.	Cancer Cell	2015
25886852	Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks.	Genome Biol	2015
25781952	Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.	PLoS One	2015
25797355	Comparative analysis of primary tumour and matched metastases in colorectal cancer patients: evaluation of concordance between genomic and transcriptional profiles.	Eur J Cancer	2015
23448145	MeCP2 regulates ethanol sensitivity and intake.	Addict Biol	2014
24980976	Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats.	Mol Neurodegener	2014
24823640	Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.	Cancer Cell	2014
24636978	Chk1 as a new therapeutic target in triple-negative breast cancer.	Breast	2014
24365559	Crohn's disease susceptibility variants in Colombian tuberculosis patients.	Int J Tuberc Lung Dis	2014
23178486	STK38 is a critical upstream regulator of MYC's oncogenic activity in human B-cell lymphoma.	Oncogene	2013
24652136	Variants in the IFNÎ³ transcription factor genes TBET, STAT1, STAT4, and HLX and the risk of pulmonary tuberculosis in a Colombian population: a case-control study.	Biomedica	2013
24244136	Practical guidelines for the comprehensive analysis of ChIP-seq data.	PLoS Comput Biol	2013
23918374	ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.	Proc Natl Acad Sci U S A	2013
23630076	Survival factor NFIL3 restricts FOXO-induced gene expression in cancer.	Genes Dev	2013
23736082	Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor.	Nat Commun	2013
22260765	Uterine perforation by a cystoperitoneal shunt, an unusual cause of recurrent vaginal discharge.	J Obstet Gynaecol Can	2012
23023127	Structure-based prediction of protein-protein interactions on a genome-wide scale.	Nature	2012
22815528	Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.	Cancer Res	2012
22836754	B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer.	Cancer Res	2012
22221660	Evaluation of Toll-like receptor and adaptor molecule polymorphisms for susceptibility to tuberculosis in a Colombian population.	Int J Immunogenet	2012
22246697	Reverse-engineering human regulatory networks.	Wiley Interdiscip Rev Syst Biol Med	2012
20531406	A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.	Mol Syst Biol	2010
24846105	From clinical sites to biorepositories: effectiveness in blood sample management.	Biopreserv Biobank	2010
19201773	Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.	Gut	2009
18047540	ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands.	Am J Gastroenterol	2008
19079170	Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.	Mucosal Immunol	2008
18650832	MAST3: a novel IBD risk factor that modulates TLR4 signaling.	Genes Immun	2008
18277385	A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas.	Mol Syst Biol	2008
17646307	Comparative analysis of microarray normalization procedures: effects on reverse engineering gene networks.	Bioinformatics	2007

1 - 50 of 57

Ganiraju C Manyam

the University of Texas MD Anderson Cancer Center

Career Start Year 2009

Number of shared co-authors 1

James C Costello

University of Colorado Anschutz Medical Campus

Career Start Year 2006

Number of shared co-authors 3

Matti Nykter

Prostate Cancer Research Center, Tampere University and Tays Cancer Center

Career Start Year 2006

Number of shared co-authors 1

Steffen Durinck

Genentech Inc.

Career Start Year 2004

Number of shared co-authors 0

Amy G Robertson

Present address: Dxige Research Inc.

Career Start Year 2003

Number of shared co-authors 3

Obi L Griffith

Washington University

Career Start Year 2003

Number of shared co-authors 0

Andrew V Kossenkov

The Wistar Institute

Career Start Year 2003

Number of shared co-authors 0

Jianmin Wang

Roswell Park Comprehensive Cancer Center

Career Start Year 2003

Number of shared co-authors 0

Michael Slifker

Fox Chase Cancer Center

Career Start Year 2002

Number of shared co-authors 1

Olivier Elemento

Meyer Cancer Center

Career Start Year 2002

Number of shared co-authors 4

Joel S Parker

Lineberger Cancer Center, University of North Carolina

Career Start Year 2002

Number of shared co-authors 4

Syed Haider

Institute of Cancer Research

Career Start Year 2002

Number of shared co-authors 0

Mikhail G Dozmorov

Virginia Commonwealth University

Career Start Year 2001

Number of shared co-authors 0

Vladimir Makarov

Center for Immunotherapy and Precision-Immuno-Oncology, Cleveland Clinic

Career Start Year 2001

Number of shared co-authors 5

Yan W Asmann

Mayo Clinic

Career Start Year 2000

Number of shared co-authors 0

Andrew J Gentles

Stanford Center for Biomedical Informatics Research, Stanford University

Career Start Year 1999

Number of shared co-authors 3

Shawn Levy

HudsonAlpha Institute for Biotechnology

Career Start Year 1999

Number of shared co-authors 4

Paul T Spellman

Oregon Health & Science University Hospital.

Career Start Year 1998

Number of shared co-authors 2

Lianbo Yu

The Ohio State University

Career Start Year 1997

Number of shared co-authors 0

Shannon K McWeeney

Oregon Health & Science University, University of California Berkeley

Career Start Year 1997

Number of shared co-authors 2

Benedikt Brors

German Cancer Research Center (DKFZ)

Career Start Year 1997

Number of shared co-authors 1

Sudhir Varma

Center for Cancer Research, National Cancer Institute

Career Start Year 1994

Number of shared co-authors 0

Anamaria A Camargo

Hospital Sirio-Libanes

Career Start Year 1994

Number of shared co-authors 0

Samuel Aparicio

University of British Columbia

Career Start Year 1993

Number of shared co-authors 3

Adam B Olshen

12224University of California san francisco

Career Start Year 1993

Number of shared co-authors 3

Sean M Grimmond

The University of Melbourne

Career Start Year 1990

Number of shared co-authors 0

Luigi Marchionni

Weill-Cornell School of Medicine

Career Start Year 1989

Number of shared co-authors 1

Eivind Hovig

Center for Bioinformatics, University of Oslo

Career Start Year 1987

Number of shared co-authors 0

Sean Davis

Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington

Career Start Year 1974

Number of shared co-authors 1

Paul C Boutros

University of California los angeles

Career Start Year 1970

Number of shared co-authors 8

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