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Author Details

Ragunath Singaravelu
Ottawa Hospital Research Institute
2010
42
17
PMIDPaper TitleJournal TitlePublished Year
36713447CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.Front Immunol2023
37822719A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.Mol Ther Methods Clin Dev2023
37236967Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.Nat Commun2023
37100284Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.J Biol Chem2023
34687845Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection.Mol Ther2022
35393414Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.Nat Commun2022
35526097Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.Mol Ther2022
33450181Profiling of MicroRNA Targets Using Activity-Based Protein Profiling: Linking Enzyme Activity to MicroRNA-185 Function.Cell Chem Biol2021
33706157SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.Biosens Bioelectron2021
33668756Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.Int J Mol Sci2021
33809836A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion.Nanomaterials (Basel)2021
33578036Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.Mol Ther2021
34459810Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter.J Vis Exp2021
34658235Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern.ACS Infect Dis2021
32297534Engineering vaccinia virus as an immunotherapeutic battleship to overcome tumor heterogeneity.Expert Opin Biol Ther2020
32872641Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.Membranes (Basel)2020
32722184Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis.Cancers (Basel)2020
30875126Concise Review: Targeting Cancer Stem Cells and Their Supporting Niche Using Oncolytic Viruses.Stem Cells2019
31694919A conserved miRNA-183 cluster regulates the innate antiviral response.J Biol Chem2019
31428674Deletion of Apoptosis Inhibitor F1L in Vaccinia Virus Increases Safety and Oncolysis for Cancer Therapy.Mol Ther Oncolytics2019
29321595MicroRNA-7 mediates cross-talk between metabolic signaling pathways in the liver.Sci Rep2018
30528902MicroRNA-124 Regulates Fatty Acid and Triglyceride Homeostasis.iScience2018
28428217microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis.Arterioscler Thromb Vasc Biol2017
27475325The role of microRNAs in metabolic interactions between viruses and their hosts.Curr Opin Virol2016
276826806-Hydroxydopamine Inhibits the Hepatitis C Virus through Alkylation of Host and Viral Proteins and the Induction of Oxidative Stress.ACS Infect Dis2016
26002865Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis.Circ Res2015
26479438MicroRNAs regulate the immunometabolic response to viral infection in the liver.Nat Chem Biol2015
27622463Soraphen A: A Probe for Investigating the Role of de Novo Lipogenesis during Viral Infection.ACS Infect Dis2015
26182401Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity.Can J Microbiol2015
23897856Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis.Hepatology2014
25008545Stearoyl-CoA desaturase inhibition blocks formation of hepatitis C virus-induced specialized membranes.Sci Rep2014
24980280Investigating the antiviral role of cell death-inducing DFF45-like effector B in HCV replication.FEBS J2014
24721496Hepatitis C virus and microRNAs: miRed in a host of possibilities.Curr Opin Virol2014
23826122Fluorescence lifetime imaging of alterations to cellular metabolism by domain 2 of the hepatitis C virus core protein.PLoS One2013
24161736Human serum activates CIDEB-mediated lipid droplet enlargement in hepatoma cells.Biochem Biophys Res Commun2013
22430896Systems biology methods help develop a better understanding of hepatitis C virus-induced liver injury.Hepatology2012
21185047Competing roles of microRNA-122 recognition elements in hepatitis C virus RNA.Virology2011
21819044Enhanced specificity of the viral suppressor of RNA silencing protein p19 toward sequestering of human microRNA-122.Biochemistry2011
21321552Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy.Nat Chem Biol2011
21284927An enzyme-linked assay for the rapid quantification of microRNAs based on the viral suppressor of RNA silencing protein p19.Anal Biochem2011
20181094Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe.Proteome Sci2010
20549003Host-virus interactions during hepatitis C virus infection: a complex and dynamic molecular biosystem.Mol Biosyst2010
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Collaborators

John C Bell
Ottawa Hospital Research Institute
Co-authored papers 15
Taha Azad
Ottawa Hospital Research Institute
Co-authored papers 15
Carolina S Ilkow
Ottawa Hospital Research Institute
Co-authored papers 14
Mathieu J F Crupi
Cancer Research Institute, Queen's University
Co-authored papers 12
Jean-Simon Diallo
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers 10
Zaid Taha
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers 10
Joanna Poutou
Ottawa Hospital Research Institute
Co-authored papers 8
Julia Petryk
Ottawa Hospital Research Institute
Co-authored papers 8
Adrian Pelin
University of Ottawa
Co-authored papers 8
Abera Surendran
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers 7
Xiao-Peng He
Ottawa Hospital Research Institute
Co-authored papers 6
Katey J Rayner
University of Ottawa
Co-authored papers 4
Dominic G Roy
Centre de Recherche du Centre Hospitalier de l'Universite de Montreal
Co-authored papers 3
Kathryn J Moore
Co-authored papers 2
Christiano Tanese de Souza
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers 2
Victoria A Jennings
Leeds Institute of Medical Research at St James's, University of Leeds
Co-authored papers 2
Rebecca C Auer
The Ottawa Hospital Research Institute
Co-authored papers 2
Sarwat T Khan
Ottawa Hospital Research Institute
Co-authored papers 2
Michele Geoffrion
University of Ottawa Heart Institute
Co-authored papers 2
Derrick Gibbings
University of Ottawa
Co-authored papers 1
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
Alan Melcher
The Institute of Cancer Research
Co-authored papers 1
Hayley E McKay
Ottawa Hospital Research Institute
Co-authored papers 1
Larissa A Pikor
Ottawa Hospital Research Institute
Co-authored papers 1
Emily E F Brown
Ottawa Hospital Research Institute
Co-authored papers 1
Egon J Jacobus
Ottawa Hospital Research Institute
Co-authored papers 1
Benjamin F Cravatt
Scripps Research Institute
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Taylor Jamieson
Ottawa Hospital Research Institute
Co-authored papers 1
Avijit Chatterjee
The Ottawa Hospital
Co-authored papers 1
Release 1.2