Author details

Full Name

Joanne Berghout

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34252934	'Single-subject studies'-derived analyses unveil altered biomechanisms between very small cohorts: implications for rare diseases.	Bioinformatics	2021
32859146	binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions.	BMC Bioinformatics	2020
32308852	Interpretation of 'Omics dynamics in a single subject using local estimates of dispersion between two transcriptomes.	AMIA Annu Symp Proc	2020
33138767	Correction to: binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions.	BMC Bioinformatics	2020
30864332	Precision drug repurposing via convergent eQTL-based molecules and pathway targeting independent disease-associated polymorphisms.	Pac Symp Biocomput	2019
29272327	Developing a 'personalome' for precision medicine: emerging methods that compute interpretable effect sizes from single-subject transcriptomes.	Brief Bioinform	2019
30864345	Workshop during the Pacific Symposium of Biocomputing, Jan 3-7, 2019: Reading between the genes: interpreting non-coding DNA in high-throughput.	Pac Symp Biocomput	2019
29218900	Single subject transcriptome analysis to identify functionally signed gene set or pathway activity.	Pac Symp Biocomput	2018
30598089	Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities.	BMC Med Genomics	2018
29218909	Reading Between the Genes: Computational Models to Discover Function from Noncoding DNA.	Pac Symp Biocomput	2018
27721430	USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.	Nat Immunol	2017
29016970	A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations.	J Am Med Inform Assoc	2017
28589853	N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes.	BMC Med Genomics	2017
28007582	kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects.	J Biomed Inform	2017
27535533	Analysis of protein-coding genetic variation in 60,706 humans.	Nature	2016
27482468	Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions.	NPJ Genom Med	2016
27849203	Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.	Nat Immunol	2016
27830251	Biomechanisms of Comorbidity: Reviewing Integrative Analyses of Multi-omics Datasets and Electronic Health Records.	Yearb Med Inform	2016
25452553	THEMIS is required for pathogenesis of cerebral malaria and protection against pulmonary tuberculosis.	Infect Immun	2015
24163257	The mouse Gene Expression Database (GXD): 2014 update.	Nucleic Acids Res	2014
25403443	CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation.	J Exp Med	2014
23594960	Susceptibility to lethal cerebral malaria is regulated by epistatic interaction between chromosome 4 (Berr6) and chromosome 1 (Berr7) loci in mice.	Genes Immun	2013
23853600	Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.	PLoS Pathog	2013
21833022	Genetic diversity in human erythrocyte pyruvate kinase.	Genes and Immunity	2012
22949651	Evidence for additive and interaction effects of host genotype and infection in malaria.	Proc Natl Acad Sci U S A	2012
22363534	An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria.	PLoS One	2012
21116636	Host resistance to malaria: using mouse models to explore the host response.	Mamm Genome	2011
19865103	Identification of a novel cerebral malaria susceptibility locus (Berr5) on mouse chromosome 19.	Genes and Immunity	2010
19717339	Genetic and genomic analyses of host-pathogen interactions in malaria.	Trends in Parasitology	2009
18487038	Spread and persistence of a rugulosin-producing endophyte in Picea glauca seedlings.		2008
18426986	C5 deficiency and C5a or C5aR blockade protects against cerebral malaria.	J Exp Med	2008
17409324	Mutations in VANGL1 associated with neural-tube defects.	N Engl J Med	2007
16861630	Cardiac failure in C5-deficient A/J mice after Candida albicans infection.	Infection and Immunity	2006
15776995	Indoor environmental quality in homes of asthmatic children on the Elsipogtog Reserve (NB), Canada.	International Journal of Circumpolar Health	2005
15042272	Modification of the Limulus amebocyte lysate assay for the analysis of glucan in indoor environments.	Analytical and Bioanalytical Chemistry	2004