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Author Details

Daniel C Link
Washington University School of Medicine
1982
273
91
PMIDPaper TitleJournal TitlePublished Year
36711871Genomic landscape of <i>TP53</i> -mutated myeloid malignancies.medRxiv2023
37838759Idasanutlin and navitoclax induce synergistic apoptotic cell death in T-cell acute lymphoblastic leukemia.Leukemia2023
36949552The reverse transcriptase inhibitor 3TC protects against age-related cognitive dysfunction.Aging Cell2023
37339484Genomic landscape of TP53-mutated myeloid malignancies.Blood Adv2023
37235557Clonal hematopoiesis in survivors of childhood cancer.Blood Adv2023
36480766Clonal Hematopoiesis and Risk of Incident Lung Cancer.J Clin Oncol2023
36853803Increased clonal hematopoiesis involving DNA damage response genes in patients undergoing lung transplantation.JCI Insight2023
36443249TDP-43 knockdown in mouse model of ALS leads to dsRNA deposition, gliosis, and neurodegeneration in the spinal cord.Cereb Cortex2023
34115842Heterozygous variants of CLPB are a cause of severe congenital neutropenia.Blood2022
35709710Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression.Blood Cancer Discov2022
35675516IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function.Blood2022
35439167TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche.J Clin Invest2022
35429619Recurrent transcriptional responses in AML and MDS patients treated with decitabine.Exp Hematol2022
36410860Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine.ACS Chem Neurosci2022
35895896Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.Blood2022
34873300Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells.Leukemia2022
35236053Decitabine salvage for <i>TP53</i>-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy.Haematologica2022
35019859Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia.Blood Cancer Discov2022
34810038Organ-on-a-chip model of vascularized human bone marrow niches.Biomaterials2022
32862276The gut microbiome-derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging.Geroscience2021
33704937Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers.N Engl J Med2021
33556431TLR7/8 agonist treatment induces an increase in bone marrow resident dendritic cells and hematopoietic progenitor expansion and mobilization.Exp Hematol2021
33914880Application of a bioinformatic pipeline to RNA-seq data identifies novel virus-like sequence in human blood.G3 (Bethesda)2021
34889405Impaired myelopoiesis in congenital neutropenia: insights into clonal and malignant hematopoiesis.Hematology Am Soc Hematol Educ Program2021
34737755Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice.Front Immunol2021
34464705Amyloid beta acts synergistically as a pro-inflammatory cytokine.Neurobiol Dis2021
34845035Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.Proc Natl Acad Sci U S A2021
34104888Is There a Brain Microbiome?Neurosci Insights2021
34215620Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring <i>SF3B1</i> or <i>U2AF1</i> Mutations.Cancer Res2021
32463886Shaping clonal hematopoiesis.Blood2020
34661135Soil and Seed: Coconspirators in Therapy-Induced Myeloid Neoplasms.Blood Cancer Discov2020
31949165A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration.Nat Commun2020
33027668TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.Cell Rep2020
32736382Clonal hematopoiesis and risk for hematologic malignancy.Blood2020
32821971Cooperating, congenital neutropenia-associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs.Ann Hematol2020
32760056Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.PLoS Biol2020
32724180Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.Nat Commun2020
32477458Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow.Oncotarget2020
32470079Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions.PLoS One2020
30431463Mechanisms of leukemic transformation in congenital neutropenia.Curr Opin Hematol2019
31204302TGF-β Signaling Plays an Essential Role in the Lineage Specification of Mesenchymal Stem/Progenitor Cells in Fetal Bone Marrow.Stem Cell Reports2019
31402259MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells.Immunity2019
31229690TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes.Neurobiol Dis2019
31039135Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking.J Clin Invest2019
30770874Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation.Cell Death Differ2019
31004062α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer's disease.Proc Natl Acad Sci U S A2019
30765536Heterochromatin anomalies and double-stranded RNA accumulation underlie <i>C9orf72</i> poly(PR) toxicity.Science2019
31085833Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells.J Clin Invest2019
30792577Neurodegeneration, Heterochromatin, and Double-Stranded RNA.J Exp Neurosci2019
30958820Heat shock in C. elegans induces downstream of gene transcription and accumulation of double-stranded RNA.PLoS One2019
  • 1 - 50 of 273

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Collaborators

Timothy J Ley
Washington University School of Medicine
Co-authored papers 55
John F DiPersio
Washington University School of Medicine
Co-authored papers 48
Matthew J Walter
Washington University School of Medicine in St. Louis
Co-authored papers 43
Peter Westervelt
Washington University School of Medicine
Co-authored papers 38
Robert S Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 37
Sharon E Heath
Washington University School of Medicine.
Co-authored papers 36
Richard K Wilson
The Ohio State University
Co-authored papers 32
Christopher A Miller
Washington University School of Medicine
Co-authored papers 31
Timothy A Graubert
Massachusetts General Hospital
Co-authored papers 30
Elaine R Mardis
The Ohio State University
Co-authored papers 26
Jacqueline E Payton
Washington University School of Medicine.
Co-authored papers 25
Catrina Fronick
McDonnell Genome Institute, Washington University in St. Louis School of Medicine
Co-authored papers 18
Michelle O'Laughlin
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 18
Michael D McLellan
McDonnell Genome Institute, Washington University in St. Louis
Co-authored papers 16
Li Ding
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 15
Mark A Watson
Washington University School of Medicine
Co-authored papers 13
Matthew J Christopher
Washington University School of Medicine
Co-authored papers 13
Vincent Magrini
The Ohio State University
Co-authored papers 13
David H Spencer
Washington University School of Medicine.
Co-authored papers 12
Rakesh Nagarajan
Current or past members of the College of American Pathologists
Co-authored papers 12
Leonard Petrucelli
Co-authored papers 11
David E Larson
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 11
Daniel C Koboldt
Institute for Genomic Medicine, Nationwide Children's Hospital
Co-authored papers 11
Lukas D Wartman
Washington University School of Medicine in St. Louis
Co-authored papers 9
Jeffery M Klco
St. Jude Children's Research Hospital
Co-authored papers 9
Tamara L Lamprecht
St. Jude Children's Research Hospital
Co-authored papers 8
Thomas E Johnson
Institute for Behavioral Genetics, University of Colorado Boulder
Co-authored papers 8
Ken Chen
University of Texas MD Anderson Cancer Center
Co-authored papers 7
Tania F Gendron
Co-authored papers 7
Maria Trissal
Co-authored papers 7
Release 1.2