Author details

Full Name

Rong Chen

Affiliation

ORCID

Career Start Year

2006

Papers

109

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36749379	Antibiotics-induced dysbiosis in gut microbiota affects bumblebee health via regulating host amino acid metabolism.		2023
35295598	Inpatient Administration of Alpha-1-Adrenergic Receptor Blocking Agents Reduces Mortality in Male COVID-19 Patients.	Front Med (Lausanne)	2022
35673908	[Interference of P2X4 receptor expression in tumor-associated macrophages suppresses migration and invasion of glioma cells].	Nan fang yi ke da xue xue bao = Journal of Southern Medical University	2022
36187617	Circulating (1 â¿¿ 3)-Î²-D-Glucan as an immune activation marker decreased after ART in people living with HIV.	Frontiers in Public Health	2022
35298662	Targeted Next-Generation Sequencing Reveals Exceptionally High Rates of Molecular Driver Mutations in Never-Smokers With Lung Adenocarcinoma.	Oncologist	2022
33221858	USP8 and TP53 Drivers are Associated with CNV in a Corticotroph Adenoma Cohort Enriched for Aggressive Tumors.	J Clin Endocrinol Metab	2021
33490583	The complete chloroplast genome sequence of cv. : a most famous variety of Wuyi tea (Synonym: L.).	Mitochondrial DNA Part B: Resources	2021
33680693	Constructing and validating a diagnostic nomogram for multiple sclerosis via bioinformatic analysis.	3 Biotech	2021
34159287	Parafibromin Abnormalities in Ossifying Fibroma.	J Endocr Soc	2021
33733072	A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma.	iScience	2021
33882890	A composite biomarker of neutrophil-lymphocyte ratio and hemoglobin level correlates with clinical response to PD-1 and PD-L1 inhibitors in advanced non-small cell lung cancers.	BMC Cancer	2021
33829580	Analysis of Real-World Data to Investigate the Impact of Race and Ethnicity on Response to Programmed Cell Death-1 and Programmed Cell Death-Ligand 1 Inhibitors in Advanced Non-Small Cell Lung Cancers.	Oncologist	2021
34144038	Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles.	J Biol Chem	2021
34028782	A novel 12-gene signature as independent prognostic model in stage IA and IB lung squamous cell carcinoma patients.		2021
32606442	Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals.	Genet Med	2020
32267205	Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial.	Emerging Microbes and Infections	2020
32354599	Use of comedications and potential drug-drug interactions in people living with HIV in China.	Journal of Infection and Chemotherapy	2020
32957400	Comparative efficacy and safety of mycophenolate mofetil and cyclophosphamide in the induction treatment of lupus nephritis: A systematic review and meta-analysis.	Medicine (United States)	2020
32511564	Acute Kidney Injury in Hospitalized Patients with COVID-19.	medRxiv	2020
33173861	Sex differences in viral entry protein expression and host transcript responses to SARS-CoV-2.	Res Sq	2020
33109676	Hospitalised COVID-19 patients of the Mount Sinai Health System: a retrospective observational study using the electronic medical records.	BMJ Open	2020
32838647	Pharmacogenomics and pharmacokinetics of efavirenz 400Â or 600Â mg in 184 treatment-naive HIV-infected patients in China.	Pharmacogenomics	2020
32609658	Dynamics of HBV surface antigen related end points in chronic hepatitis B infection: a systematic review and meta-analysis.	Antiviral Therapy	2020
31308697	upregulates TRPC6 via Wnt/Î²-catenin signaling to promote gastric cancer migration and invasion.	OncoTargets and Therapy	2019
31684948	Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits.	BMC Med Genomics	2019
31131321	A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer.	Sci Adv	2019
31266448	Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans.	BMC Genet	2019
30848458	Leveraging Big Data to Transform Drug Discovery.	Methods Mol Biol	2019
31345219	Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits.	BMC Med Genomics	2019
28200013	Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning.	Brief Bioinform	2018
29218877	Automated disease cohort selection using word embeddings from Electronic Health Records.	Pac Symp Biocomput	2018
29218870	Loss-of-function of neuroplasticity-related genes confers risk for human neurodevelopmental disorders.	Pac Symp Biocomput	2018
29726959	Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.	J Clin Endocrinol Metab	2018
28051114	Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach.	Sci Rep	2017
28982267	Institutional profile: translational pharmacogenomics at the Icahn School of Medicine at Mount Sinai.	Pharmacogenomics	2017
28487882	Identification of a novel <i>RASD1</i> somatic mutation in a <i>USP8</i>-mutated corticotroph adenoma.	Cold Spring Harb Mol Case Stud	2017
28974674	Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.	Nat Commun	2017
28352668	Genomic profiling reveals mutational landscape in parathyroid carcinomas.	JCI Insight	2017
29082853	Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications.	Genome Med	2017
26975230	The CYP2D6 VCF Translator.	Pharmacogenomics J	2017
27896999	IDENTIFY CANCER DRIVER GENES THROUGH SHARED MENDELIAN DISEASE PATHOGENIC VARIANTS AND CANCER SOMATIC MUTATIONS.	Pac Symp Biocomput	2017
27649553	Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer.	Clin Cancer Res	2017
27539938	Acute Intermittent Porphyria: Predicted Pathogenicity of HMBS Variants Indicates Extremely Low Penetrance of the Autosomal Dominant Disease.	Human Mutation	2016
27065010	Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases.	Nat Biotechnol	2016
27245685	Development and clinical application of an integrative genomic approach to personalized cancer therapy.	Genome Med	2016
26746786	Integrating 400 million variants from 80,000 human samples with extensive annotations: towards a knowledge base to analyze disease cohorts.	BMC Bioinformatics	2016
27358062	A loss of function variant in CASP7 protects against Alzheimer's disease in homozygous APOE Îµ4 allele carriers.	BMC Genomics	2016
27307606	Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.	Bioinformatics	2016
27115429	Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants.	PLoS Comput Biol	2016
26363178	DIVAS: a centralized genetic variant repository representing 150,000 individuals from multiple disease cohorts.		2016