Author details

Full Name

Yiping He

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35184277	Joint gene network construction by single-cell RNA sequencing data.	Biometrics	2023
37760589	Repurposing Clemastine to Target Glioblastoma Cell Stemness.	Cancers (Basel)	2023
36828904	Rewiring of the N-Glycome with prostate cancer progression and therapy resistance.	NPJ Precis Oncol	2023
37131619	Interplay between and mutations governs innate immune responses in diffuse gliomas.		2023
36752189	Oncofetal protein glypican-3 is a biomarker and critical regulator of function for neuroendocrine cells in prostate cancer.	J Pathol	2023
35264604	MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization.	Scientific Reports	2022
35453502	Purine Synthesis Inhibitor L-Alanosine Impairs Mitochondrial Function and Stemness of Brain Tumor Initiating Cells.	Biomedicines	2022
34732238	TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.	Acta neuropathologica communications	2021
33753479	A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer.	Proc Natl Acad Sci U S A	2021
33583275	Low levels of BRCA1 protein expression predict a worse prognosis in stage I-II colon cancer.	International Journal of Biological Markers	2021
33441554	Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.	Nat Commun	2021
34521764	Epigenetic Regulation of Fanconi Anemia Genes Implicates PRMT5 Blockage as a Strategy for Tumor Chemosensitization.	Molecular Cancer Research	2021
32555164	The integrated genomic and epigenomic landscape of brainstem glioma.	Nature Communications	2020
32229503	Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.	Molecular Cancer Research	2020
31533041	A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis.	Cell Reports	2019
31801883	Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer.	Sci Transl Med	2019
30346624	Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas.	Neuro-Oncology	2019
30478739	Hereditary brain tumor with a homozygous germline mutation in PMS2: pedigree analysis and prenatal screening in a family with constitutional mismatch repair deficiency (CMMRD) syndrome.	Familial Cancer	2019
31292202	CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP.	Molecular Cancer Research	2019
31040154	MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation.	Cancer Research	2019
29802247	The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.	Nat Commun	2018
30131529	Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells.	Sci Rep	2018
29097607	Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1-Induced Metabolic Liabilities.	Cancer Research	2018
28148827	Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression.	Molecular Cancer Research	2017
28939681	Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation.	Cancer Research	2017
29100338	Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors.	Oncotarget	2017
27481176	Alternative Splicing Provides a Novel Molecular Mechanism for Prostatic Small-cell Neuroendocrine Carcinoma.	Eur Urol	2017
27803045	Molecular Signature to Risk-Stratify Prostate Cancer of Intermediate Risk.	Clin Cancer Res	2017
26506520	Prevalence of deleterious ATM germline mutations in gastric cancer patients.	Oncotarget	2015
24880341	Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.	Nature Genetics	2014
24140581	The genetic landscape of anaplastic astrocytoma.	Oncotarget	2014
23659599	Clinico-pathological description of three paediatric medulloblastoma cases with MLL2/3 gene mutations.	Neuropathol Appl Neurobiol	2014
24722048	Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas.	Oncotarget	2014
25198066	Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma.	PLoS One	2014
23204232	Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.	Cancer Research	2013
24240169	KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.	Oncotarget	2013
23530248	TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.	Proc Natl Acad Sci U S A	2013
23045699	Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways.	Proc Natl Acad Sci U S A	2012
22885298	Mutant IDH1 is required for IDH1 mutated tumor cell growth.	Oncotarget	2012
22869205	Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.	Oncotarget	2012
22558385	Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells.	PLoS One	2012
21719641	Altered telomeres in tumors with ATRX and DAXX mutations.	Science	2011
21163964	The genetic landscape of the childhood cancer medulloblastoma.	Science	2011
21289278	Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome.	Proceedings of the National Academy of Sciences of the United States of America	2011
20200521	Heteroplasmic mitochondrial DNA mutations in normal and tumour cells.	Nature	2010
19605688	Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.	Genes and Development	2009
19684580	Sensitive digital quantification of DNA methylation in clinical samples.	Nature Biotechnology	2009
18495772	Primary human hepatocytes are susceptible to infection by hepatitis delta virus assembled with envelope proteins of woodchuck hepatitis virus.	Journal of Virology	2008
19056939	The antisense transcriptomes of human cells.	Science	2008
17671232	Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.	Blood	2007