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Author Details
Full Name
Ville Mustonen
Affiliation
University of Helsinki
ORCID
Career Start Year
2004
Papers
53
H Index
27
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36596459
Understanding cellular growth strategies via optimal control.
J R Soc Interface
2023
37498846
Time-travelling pathogens and their risk to ecological communities.
PLoS Comput Biol
2023
37400577
Steering and controlling evolution - from bioengineering to fighting pathogens.
Nat Rev Genet
2023
36697836
Author Correction: The repertoire of mutational signatures in human cancer.
Nature
2023
36068219
The mutational signatures of formalin fixation on the human genome.
Nat Commun
2022
35784450
Strong selective environments determine evolutionary outcome in time-dependent fitness seascapes.
Evol Lett
2022
36474143
Identification of multiplicatively acting modulatory mutational signatures in cancer.
BMC Bioinformatics
2022
33408222
Genomic Epidemiology and Evolution of <i>Escherichia coli</i> in Wild Animals in Mexico.
mSphere
2021
34555024
Drug-induced resistance evolution necessitates less aggressive treatment.
PLoS Comput Biol
2021
34427505
Machine Learning Prediction of Resistance to Subinhibitory Antimicrobial Concentrations from Escherichia coli Genomes.
mSystems
2021
32778754
Repeatable ecological dynamics govern the response of experimental communities to antibiotic pulse perturbation.
Nat Ecol Evol
2020
32025018
The repertoire of mutational signatures in human cancer.
Nature
2020
33370253
Multiobjective optimization identifies cancer-selective combination therapies.
PLoS Comput Biol
2020
32737164
Eco-evolutionary control of pathogens.
Proc Natl Acad Sci U S A
2020
30657986
Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales.
Mol Biol Evol
2019
31738747
Contrasting the impact of cytotoxic and cytostatic drug therapies on tumour progression.
PLoS Comput Biol
2019
28958783
Evaluating genetic drift in time-series evolutionary analysis.
J Theor Biol
2018
30072377
Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells.
Genetics
2018
30177804
The evolutionary landscape of colorectal tumorigenesis.
Nat Ecol Evol
2018
30550564
Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome data.
PLoS Comput Biol
2018
28704525
Rapid identification of genes controlling virulence and immunity in malaria parasites.
PLoS Pathog
2017
29045840
Clonal Heterogeneity Influences the Fate of New Adaptive Mutations.
Cell Rep
2017
28812721
Predicting evolution.
Nat Ecol Evol
2017
27135926
Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
Nature
2016
26414517
Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.
J Pathol
2016
27121471
Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.
Blood
2016
25587136
The value of monitoring to control evolving populations.
Proc Natl Acad Sci U S A
2015
26125594
Pathway and network analysis of cancer genomes.
Nat Methods
2015
24425782
A high-definition view of functional genetic variation from natural yeast genomes.
Mol Biol Evol
2014
25080215
Identifying selection in the within-host evolution of influenza using viral sequence data.
PLoS Comput Biol
2014
24882004
High-definition reconstruction of clonal composition in cancer.
Cell Rep
2014
23628380
EMu: probabilistic inference of mutational processes and their localization in the cancer genome.
Genome Biol
2013
24037264
High-resolution mapping of complex traits with a four-parent advanced intercross yeast population.
Genetics
2013
23900255
Computational approaches to identify functional genetic variants in cancer genomes.
Nat Methods
2013
23658715
Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses.
PLoS One
2013
22114362
Quantifying selection acting on a complex trait using allele frequency time series data.
Mol Biol Evol
2012
23171476
GraphAlignment: Bayesian pairwise alignment of biological networks.
BMC Syst Biol
2012
23300444
Components of selection in the evolution of the influenza virus: linkage effects beat inherent selection.
PLoS Pathog
2012
22223745
A method to infer positive selection from marker dynamics in an asexual population.
Bioinformatics
2012
21248752
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.
Nature
2011
21995386
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.
N Engl J Med
2011
21926305
Emergent neutrality in adaptive asexual evolution.
Genetics
2011
21900272
Distinguishing driver and passenger mutations in an evolutionary history categorized by interference.
Genetics
2011
21441214
Germline fitness-based scoring of cancer mutations.
Genetics
2011
20145113
Fitness flux and ubiquity of adaptive evolution.
Proc Natl Acad Sci U S A
2010
19232770
From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation.
Trends Genet
2009
18352233
Molecular evolution under fitness fluctuations.
Phys Rev Lett
2008
18723669
Energy-dependent fitness: a quantitative model for the evolution of yeast transcription factor binding sites.
Proc Natl Acad Sci U S A
2008
17287357
Adaptations to fluctuating selection in Drosophila.
Proc Natl Acad Sci U S A
2007
15903492
Equilibrium statistical mechanics of a grain boundary.
Phys Rev E Stat Nonlin Soft Matter Phys
2005
1 - 50 of 53
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row(s) 1 - 30 of 30
Collaborators
Adam Butler
Wellcome Sanger Institute
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Wellcome Sanger Institute
Co-authored papers
4
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Wellcome Sanger Institute
Co-authored papers
4
Nuria Lopez-Bigas
Universitat Pompeu Fabra
Co-authored papers
4
Ludmil B Alexandrov
Moores Cancer Center, university of california san diego
Co-authored papers
3
Phillip A Futreal
The University of Texas MD Anderson Cancer Center
Co-authored papers
3
Jon Teague
Wellcome Sanger Institute
Co-authored papers
3
Stuart McLaren
Wellcome Trust Sanger Institute
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3
David Jones
Wellcome Sanger Institute
Co-authored papers
3
Keiran Raine
Wellcome Sanger Institute
Co-authored papers
3
Laura Mudie
Wellcome Trust Sanger Institute
Co-authored papers
2
Kyle R Covington
Baylor College of Medicine
Co-authored papers
2
John V Pearson
QIMR Berghofer Medical Research Institute
Co-authored papers
2
David C Wedge
Manchester Cancer Research Centre, University of Manchester
Co-authored papers
2
Leszek J Klimczak
National Institute of Environmental Health Sciences (NIEHS)
Co-authored papers
2
Miguel Vazquez
Norwegian University of Science and Technology
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2
Paul C Boutros
University of California los angeles
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2
Joshua M Stuart
University of California at Santa Cruz
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2
Alfonso Valencia
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Pau Creixell
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
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Dmitry A Gordenin
National Institute of Environmental Health Sciences (NIEHS)
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Chris Greenman
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