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Author Details

P??r Matsson
University of Gothenburg
2005
38
24
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35089508High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.Pharm Res2022
35488474New and Emerging Research on Solute Carrier and ATP Binding Cassette Transporters in Drug Discovery and Development: Outlook From the International Transporter Consortium.Clin Pharmacol Ther2022
32910949Drug Metabolites Potently Inhibit Renal Organic Anion Transporters, OAT1 and OAT3.J Pharm Sci2021
33739838Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes.Mol Pharm2021
33096136A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research.J Pharm Sci2021
31701258A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f<sub>u,cell</sub>).Pharm Res2019
29709195Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids.Mol Pharm2018
29981151Molecular Modeling of Drug-Transporter Interactions-An International Transporter Consortium Perspective.Clin Pharmacol Ther2018
30059145Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches.Clin Pharmacol Ther2018
29608068Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5.J Med Chem2018
28853740Erratum: Structural and conformational determinants of macrocycle cell permeability.Nat Chem Biol2017
28225057Intracellular drug bioavailability: a new predictor of system dependent drug disposition.Sci Rep2017
28234469How Big Is Too Big for Cell Permeability?J Med Chem2017
28701380Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery.Proc Natl Acad Sci U S A2017
26922253The Need for Speed-Kinetic Limits of Drug Transporters.Trends Pharmacol Sci2016
27748751Structural and conformational determinants of macrocycle cell permeability.Nat Chem Biol2016
27067608Cell permeability beyond the rule of 5.Adv Drug Deliv Rev2016
26869442Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9.J Pharm Sci2016
26869432The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition.J Pharm Sci2016
25799456Quantifying the impact of transporters on cellular drug permeability.Trends Pharmacol Sci2015
26820893Computational modeling to predict the functions and impact of drug transporters.In Silico Pharmacol2015
26216247Addendum to 'Quantifying the impact of transporters on cellular drug permeability'.Trends Pharmacol Sci2015
24524242Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.J Med Chem2014
24601604A high-throughput cell-based method to predict the unbound drug fraction in the brain.J Med Chem2014
23588306Computational prospecting for drug-transporter interactions.Clin Pharmacol Ther2013
24014644Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).Toxicol Sci2013
23631740Rapid measurement of intracellular unbound drug concentrations.Mol Pharm2013
23588320Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.Clin Pharmacol Ther2013
21383772Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.Pharmacogenomics J2012
21599003Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.J Med Chem2011
20052679Comparison of human solute carriers.Protein Sci2010
19900523Understanding polymer-lipid solid dispersions--the properties of incorporated lipids govern the crystallisation behaviour of PEG.Int J Pharm2010
19421845Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.Pharm Res2009
19742321Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation.PLoS One2009
18457386Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).J Med Chem2008
18788725Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.J Med Chem2008
17616561A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).J Pharmacol Exp Ther2007
15658873Exploring the role of different drug transport routes in permeability screening.J Med Chem2005
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Sapporo Medical University
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Shionogi & Co.
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College of Medicine, Ewha Womans University
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Leiden Academic Centre for Drug Research (LACDR), Leiden University
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