Skip to Main Content

Author Details

Sanford D Markowitz
1985
249
95
PMIDPaper TitleJournal TitlePublished Year
36782065Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.Nat Genet2023
37721804Enzymatic Resolution and Decarboxylative Functionalization of α-Sulfinyl Esters.2023
36774348Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system.Nat Commun2023
37333176NON-ENDOSCOPIC ESOPHAGEAL SAMPLING DEVICE AND BIOMARKER PANEL FOR DETECTION OF BARRETT'S ESOPHAGUS (BE) AND ESOPHAGEAL ADENOCARCINOMA (EAC).2023
36539618Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.Nat Genet2023
35276002Liver Endothelium Promotes HER3-Mediated Cell Survival in Colorectal Cancer with Wild-Type and Mutant KRAS.Molecular Cancer Research2022
35705525Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia.Clin Cancer Res2022
3558794515-PGDH regulates hematopoietic and gastrointestinal fitness during aging.PLoS ONE2022
35418124Nuclear translocation of p85β promotes tumorigenesis of PIK3CA helical domain mutant cancer.Nat Commun2022
36322935Orally Bioavailable Quinoxaline Inhibitors of 15-Prostaglandin Dehydrogenase (15-PGDH) Promote Tissue Repair and Regeneration.Journal of Medicinal Chemistry2022
35056981Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291.Pharmaceutics2021
33493502Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett's Esophagus.Gastroenterology2021
33632709Genetic architectures of proximal and distal colorectal cancer are partly distinct.Gut2021
3345912715-Hydroxyprostaglandin dehydrogenase inhibitor prevents contrast-induced acute kidney injury.Renal Failure2021
3360037715-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration.JCI insight2021
33279516Epigenetic Alterations in the Gastrointestinal Tract: Current and Emerging Use for Biomarkers of Cancer.Gastroenterology2021
34641449Structural Insights into Novel 15-Prostaglandin Dehydrogenase Inhibitors.Molecules2021
32669620Therapeutic targeting of 15-PGDH in murine pulmonary fibrosis.Scientific Reports2020
32299850Biomarkers for Early Detection of Colorectal Cancer: The Early Detection Research Network, a Framework for Clinical Translation.Cancer Epidemiol Biomarkers Prev2020
32001714Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis.Nat Commun2020
31866242Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer.Gastroenterology2020
33093162Barrett's Esophagus and Esophageal Adenocarcinoma Biomarkers.Cancer Epidemiol Biomarkers Prev2020
33135478Inhibition of 15-PGDH prevents ischemic renal injury by the PGE/EP signaling pathway mediating vasodilation, increased renal blood flow, and increased adenosine/A receptors.2020
329078365-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against <i>PIK3CA</i>-Mutant Colorectal Cancers.Cancer Res2020
30768984Systems Biology Analyses Show Hyperactivation of Transforming Growth Factor-β and JNK Signaling Pathways in Esophageal Cancer.Gastroenterology2019
31844152Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo.Sci Rep2019
30510241Discovery of common and rare genetic risk variants for colorectal cancer.Nat Genet2019
29884612Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis.Gut2019
29917119Novel Common Genetic Susceptibility Loci for Colorectal Cancer.J Natl Cancer Inst2019
31179210A Novel Blood-Based Colorectal Cancer Diagnostic Technology Using Electrical Detection of Colon Cancer Secreted Protein-2.Advanced Science2019
30759065Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes.Elife2019
29769213Chemopreventive Efficacy of the Cyclooxygenase-2 (Cox-2) Inhibitor, Celecoxib, Is Predicted by Adenoma Expression of Cox-2 and 15-PGDH.Cancer Epidemiology Biomarkers and Prevention2018
30348202The DNMT1-associated lincRNA DACOR1 reprograms genome-wide DNA methylation in colon cancer.Clinical Epigenetics2018
30193399Performance of multitarget stool DNA testing in African American patients.Cancer2018
29343623Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus.Sci Transl Med2018
29516325Evaluation of Patients with an Apparent False Positive Stool DNA Test: The Role of Repeat Stool DNA Testing.Digestive Diseases and Sciences2018
29472361A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support.Haematologica2018
29743621Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis.Sci Rep2018
27864128Prostaglandin E Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice.Gastroenterology2017
28684492Cancer bypasses the lymph nodes.Science2017
28716915Prostaglandin dehydrogenase is a target for successful induction of cervical ripening.Proc Natl Acad Sci U S A2017
28886423Molecular Imaging of Colorectal Tumors by Targeting Colon Cancer Secreted Protein-2 (CCSP-2).Neoplasia2017
28398755Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair.Journal of Medicinal Chemistry2017
28922414A nonrandomized trial of vitamin D supplementation for Barrett's esophagus.PLoS One2017
29073141Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study.PLoS ONE2017
27639802Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma.Gastroenterology2017
28169291Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome.Nat Commun2017
27790711Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms.Int J Cancer2017
28143522ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial.Trials2017
27582379Adverse Clinical Outcome Associated With Mutations That Typify African American Colorectal Cancers.J Natl Cancer Inst2016
  • 1 - 50 of 249

Recommended Authors

Collaborators

Co-authored papers 46
Co-authored papers 42
. Fred Hutchinson Cancer Center
Co-authored papers 36
Co-authored papers 22
Co-authored papers 19
Co-authored papers 19
National Cancer Institute
Co-authored papers 18
Co-authored papers 16
Case Western Reserve University School of Medicine
Co-authored papers 12
Vanderbilt Genetics Institute, Vanderbilt University Medical Center
Co-authored papers 11
The Ohio State University Comprehensive Cancer Center
Co-authored papers 9
Dana Farber Cancer Institute.
Co-authored papers 9
Co-authored papers 8
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 8
Texas Children's Hospital
Co-authored papers 8
Co-authored papers 8
Mayo Clinic
Co-authored papers 7
Center for Cancer Genetic Epidemiology, University of Cambridge
Co-authored papers 7
Co-authored papers 7
Co-authored papers 7
Case Western Reserve University School of Medicine
Co-authored papers 7
Co-authored papers 7
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 7
Co-authored papers 7
German Cancer Research Center (DKFZ)
Co-authored papers 7
Co-authored papers 6
Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
National Cancer Institute, National Institutes of Health
Co-authored papers 6