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Author Details

Syed A Hussain
University of Sheffield and Sheffield Teaching Hospitals
2001
131
36
PMIDPaper TitleJournal TitlePublished Year
35960902A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma.J Clin Oncol2023
37537253A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer.Br J Cancer2023
37258363Checkpoint Inhibitors in Urothelial Carcinoma-Future Directions and Biomarker Selection.Eur Urol2023
36862387First-line Systemic Treatment Options for Metastatic Castration-Sensitive Prostate Cancer: A Living Systematic Review and Network Meta-analysis.JAMA Oncol2023
34491610Urine DNA for monitoring chemoradiotherapy response in muscle-invasive bladder cancer: a pilot study.BJU Int2022
35577644Chemoradiotherapy in Muscle-invasive Bladder Cancer: 10-yr Follow-up of the Phase 3 Randomised Controlled BC2001 Trial.Eur Urol2022
35421369Addition of nintedanib or placebo to neoadjuvant gemcitabine and cisplatin in locally advanced muscle-invasive bladder cancer (NEOBLADE): a double-blind, randomised, phase 2 trial.Lancet Oncol2022
35388003Predictive biomarkers for survival benefit with ramucirumab in urothelial cancer in the RANGE trial.Nat Commun2022
35908256TUXEDO: A phase I/II trial of cetuximab with chemoradiotherapy in muscle-invasive bladder cancer.BJU Int2022
35142815Efficacy and Safety of Autologous Dendritic Cell-Based Immunotherapy, Docetaxel, and Prednisone vs Placebo in Patients With Metastatic Castration-Resistant Prostate Cancer: The VIABLE Phase 3 Randomized Clinical Trial.JAMA Oncol2022
33012577Perioperative Treatment in Muscle-invasive Bladder Cancer: Analysis of Secondary Endpoints in a Randomized Trial Comparing Gemcitabine and Cisplatin Versus Dose-dense Methotrexate, Vinblastine, Adriamycin, and Cisplatin.Eur Urol2021
33824031A Living, Interactive Systematic Review and Network Meta-analysis of First-line Treatment of Metastatic Renal Cell Carcinoma.Eur Urol2021
33539743Hypofractionated radiotherapy in locally advanced bladder cancer: an individual patient data meta-analysis of the BC2001 and BCON trials.Lancet Oncol2021
33558714Urological cancer patients receiving treatment during COVID-19: a single-centre perspective.Br J Cancer2021
33581875Quality of Life After Bladder Cancer: A Cross-sectional Survey of Patient-reported Outcomes.Eur Urol2021
34926759Rare case of chemotherapy-refractory metastatic vaginal squamous cell carcinoma with complete response to concurrent pembrolizumab and radiotherapy- case report and literature review.Gynecol Oncol Rep2021
34420403Novel Approach to Endoscopic Foreign Body Retrieval From the Gastric Body.J Investig Med High Impact Case Rep2021
34006497Clinical Outcomes of Platinum-ineligible Patients with Advanced Urothelial Carcinoma Treated With First-line PD1/L1 Inhibitors.Clin Genitourin Cancer2021
34171206Bladder cancer: shedding light on the most promising investigational drugs in clinical trials.Expert Opin Investig Drugs2021
33472913Phase I Trial of DNA Methyltransferase Inhibitor Guadecitabine Combined with Cisplatin and Gemcitabine for Solid Malignancies Including Urothelial Carcinoma (SPIRE).Clin Cancer Res2021
33293079Outcomes in Patients with Muscle-invasive Bladder Cancer Treated with Neoadjuvant Chemotherapy Followed by (Chemo)radiotherapy in the BC2001 Trial.Eur Urol2021
32576531The Impact of Centralised Services on Metric Reflecting High-quality Performance: Outcomes from 1110 Consecutive Radical Cystectomies at a Single Centre.Eur Urol Focus2021
31411990Incidence, Patterns, and Outcomes with Adjuvant Chemotherapy for Residual Disease After Neoadjuvant Chemotherapy in Muscle-invasive Urinary Tract Cancers.Eur Urol Oncol2020
31843338Patient-reported Quality of Life Outcomes in Patients Treated for Muscle-invasive Bladder Cancer with Radiotherapy ± Chemotherapy in the BC2001 Phase III Randomised Controlled Trial.Eur Urol2020
31753727Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial.Lancet Oncol2020
31941968CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation.Sci Rep2020
33085669Occupational bladder cancer: A cross section survey of previous employments, tasks and exposures matched to cancer phenotypes.PLoS One2020
33179000The curious case of an atypical headache, a case report and review of literature.AME Case Rep2020
32821347Correction: Inhibitor SBFI26 suppresses the malignant progression of castration-resistant PC3-M cells by competitively binding to oncogenic FABP5.Oncotarget2020
32755479Survey of the Impact of COVID-19 on Oncologists' Decision Making in Cancer.JCO Glob Oncol2020
32306987ATLANTIS: a randomised multi-arm phase II biomarker-directed umbrella screening trial of maintenance targeted therapy after chemotherapy in patients with advanced or metastatic urothelial cancer.Trials2020
32497637Analysis of Gastrointestinal and Hepatic Manifestations of SARS-CoV-2 Infection in 892 Patients in Queens, NY.Clin Gastroenterol Hepatol2020
30502102Corrigendum re: "Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens" [Eur Urol 2018;73:462-8].Eur Urol2019
31358380Mutation Analysis of the FGFR3-encoding gene Does Not Predict Response to Checkpoint Inhibitor Treatment in Metastatic Bladder Cancer.Eur Urol2019
31235192Safe Use of Immune Checkpoint Inhibitors in the Multidisciplinary Management of Urological Cancer: The European Association of Urology Position in 2019.Eur Urol2019
31113841Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer.Clin Cancer Res2019
31133463Vinflunine in the treatment of relapsed metastatic urothelial cancer: A systematic review and meta-analysis of real-world series.Crit Rev Oncol Hematol2019
28753879Robot-assisted Versus Open Radical Cystectomy in Patients Receiving Perioperative Chemotherapy for Muscle-invasive Bladder Cancer: The Oncologist's Perspective from a Multicentre Study.Eur Urol Focus2018
30116760Primary Endoscopic Closure of Duodenal Perforation Secondary to Biliary Stent Migration: A Case Report and Review of the Literature.J Investig Med High Impact Case Rep2018
31158093From Clinical Trials to Real-life Clinical Practice: The Role of Immunotherapy with PD-1/PD-L1 Inhibitors in Advanced Urothelial Carcinoma.Eur Urol Oncol2018
29273410Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens.Eur Urol2018
29268948Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial.Lancet2018
27256016Cost-effectiveness of zoledronic acid and strontium-89 as bone protecting treatments in addition to chemotherapy in patients with metastatic castrate-refractory prostate cancer: results from the TRAPEZE trial (ISRCTN 12808747).BJU Int2017
28415688Inhibitor SBFI26 suppresses the malignant progression of castration-resistant PC3-M cells by competitively binding to oncogenic FABP5.Oncotarget2017
28259975Gene expression profiling in bladder cancer identifies potential therapeutic targets.Int J Oncol2017
28402747Randomized Phase II Study Investigating Pazopanib Versus Weekly Paclitaxel in Relapsed or Progressive Urothelial Cancer.J Clin Oncol2017
28125821The predictive and prognostic value of tumour necrosis in muscle invasive bladder cancer patients receiving radiotherapy with or without chemotherapy in the BC2001 trial (CRUK/01/004).Br J Cancer2017
28098864VICTOR: Vinflunine in advanced metastatic transitional cell carcinoma of the urothelium: A retrospective analysis of the use of vinflunine in multi-centre real life setting as second line chemotherapy through Free of Charge Programme for patients in the UK and Ireland.Int J Oncol2017
28916371Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised, double-blind, phase 3 trial.Lancet2017
28923700Venous Thromboembolism Risk in Patients With Locoregional Urothelial Tract Tumors.Clin Genitourin Cancer2017
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Collaborators

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University of Washington and Fred Hutchinson Cancer Research Center
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the Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital
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Juravinski Hospital and Cancer Centre, Escarpment Cancer Research Institute
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David Geffen School of Medicine at university of california los angeles
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Liverpool University Hospitals
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Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield
Co-authored papers 2
The Institute of Cancer Research
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University Hospitals Bristol and Weston NHS Foundation Trust
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Evidence Foundation
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Astex Pharmaceuticals
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Meyer Cancer Center, Weill Cornell Medicine-NewYork Presbyterian Hospital
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University of British Columbia
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University of Montreal Health Center
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University of Toledo
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