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Author Details

Jessica A Gasser
2007
15
12
PMIDPaper TitleJournal TitlePublished Year
37095859The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein.iScience2023
37989314Genetic retargeting of E3 ligases to enhance CAR T cell therapy.2023
35763353Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells.J Clin Invest2022
33408186Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide.Science Translational Medicine2021
34027417Avadomide induces degradation of ZMYM2 fusion oncoproteins in hematologic malignancies.Blood Cancer Discov2021
33208943Small-molecule-induced polymerization triggers degradation of BCL6.Nature2020
31953384Rapid and deep-scale ubiquitylation profiling for biology and translational research.Nat Commun2020
32494016The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K.Nature2020
31043423Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs.Blood2019
30042095Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4[CRBN] activity.Blood2018
28341696A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Diabetes2017
25458846SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer.Molecular Cell2014
21108124Mechanisms underlying the anti-proliferative actions of adiponectin in human breast cancer cells, MCF7-dependency on the cAMP/protein kinase-A pathway.Nutrition and Cancer2011
20832730Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.Mol Cell2010
17914101Human adiponectin inhibits cell growth and induces apoptosis in human endometrial carcinoma cells, HEC-1-A and RL95 2.Endocrine-Related Cancer2007
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Mark A DePristo
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Harvard Medical School
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