Author details

Full Name

Diether Lambrechts

Affiliation

ORCID

Career Start Year

1994

Papers

480

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37503126	Understanding the genetic complexity of puberty timing across the allele frequency spectrum.	medRxiv	2023
35960332	Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma: Results of the phase II PRIMMO study.	Cancer Immunol Immunother	2023
35998078	The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution.	Cardiovasc Res	2023
38030622	PD-1 CD45RA effector-memory CD8 T cells and CXCL10 macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma.		2023
37566035	Intermediate Molecular Phenotypes to Identify Genetic Markers of Anthracycline-Induced Cardiotoxicity Risk.	Cells	2023
37791581	Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.		2023
37779364	Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders.		2023
37958662	Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells.		2023
37686617	Differences in the Tumor Molecular and Microenvironmental Landscape between Early (Non-Metastatic) and De Novo Metastatic Primary Luminal Breast Tumors.		2023
37479706	Obesity-associated changes in molecular biology of primary breast cancer.	Nat Commun	2023
37468466	Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection.		2023
36774883	Metabolomic and transcriptomic response to imatinib treatment of gastrointestinal stromal tumour in xenograft-bearing mice.		2023
36712139	Intermediate molecular phenotypes to identify genetic markers of anthracycline-induced cardiotoxicity risk.	bioRxiv	2023
36824750	Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.	Res Sq	2023
36572991	CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.	Cancer	2023
37451831	Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel.	J Med Genet	2023
37449970	Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features.	Clin Cancer Res	2023
36626867	Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1<sup>+</sup> T lymphocyte niches through a feed-forward loop.	Cancer Cell	2023
37245441	PARP inhibitor predictive value of the Leuven HRD test compared with Myriad MyChoice CDx PLUS HRD on 468 ovarian cancer patients from the PAOLA-1/ENGOT-ov25 trial.	Eur J Cancer	2023
36932191	Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer.		2023
37237151	Comparative analysis of deeply phenotyped GBM cohorts of 'short-term' and 'long-term' survivors.	J Neurooncol	2023
37043555	Multiomics and spatial mapping characterizes human CD8<sup>+</sup> T cell states in cancer.	Sci Transl Med	2023
37104043	C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps.		2023
35082164	Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer.	Mol Cancer Res	2022
36042336	Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.	Nature	2022
35769009	Pan-Cancer Detection and Typing by Mining Patterns in Large Genome-Wide Cell-Free DNA Sequencing Datasets.	Clin Chem	2022
35454861	CA-125 Levels Are Predictive of Survival in Low-Grade Serous Ovarian Cancer-A Multicenter Analysis.	Cancers (Basel)	2022
35653140	Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer.	Clin Cancer Res	2022
35651878	The MUC5B Promoter Polymorphism is Not Associated With Non-ILD Chronic Respiratory Diseases or Post-transplant Outcome.	Transplant International	2022
35585241	PHGDH heterogeneity potentiates cancerÂ cell dissemination and metastasis.	Nature	2022
36171010	Single-cell transcriptomics identifies pathogenic T-helper 17.1 cells and pro-inflammatory monocytes in immune checkpoint inhibitor-related pneumonitis.	Journal for ImmunoTherapy of Cancer	2022
36029799	Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study.	Lancet Respiratory Medicine,The	2022
35699412	Decoding the activated stem cell phenotype of the neonatally maturing pituitary.	eLife	2022
35882101	Timing evolution of lobular breast cancer through phylogenetic analysis.	EBioMedicine	2022
35628499	Correlation of Immunological and Molecular Profiles with Response to Crizotinib in Alveolar Soft Part Sarcoma: An Exploratory Study Related to the EORTC 90101 "CREATE" Trial.	International Journal of Molecular Sciences	2022
36338708	GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide.	Front Oncol	2022
36275702	Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates.	Frontiers in Immunology	2022
36210504	Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.	J Natl Cancer Inst	2022
35933885	Incorporating progesterone receptor expression into the PREDICT breast prognostic model.	Eur J Cancer	2022
35484288	Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer.	npj Genomic Medicine	2022
36131018	A cellular hierarchy in melanoma uncouples growth and metastasis.	Nature	2022
35931688	Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.	Nat Commun	2022
36328784	Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study.	Br J Sports Med	2022
35790747	Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis.	NPJ Breast Cancer	2022
36261534	Author Correction: A cellular hierarchy in melanoma uncouples growth and metastasis.	Nature	2022
35781107	Homologous recombination repair deficiency (HRD) testing in newly diagnosed advanced-stage epithelial ovarian cancer: A Belgian expert opinion.		2022
36423635	Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1<sup>+</sup> T lymphocyte niches through a feed-forward loop.	Cancer Cell	2022
33962884	Single-cell Transcriptomics Uncover a Novel Role of Myeloid Cells and T-lymphocytes in the Fibrotic Microenvironment in Peyronie's Disease.	European Urology Focus	2022
35042965	Rare germline copy number variants (CNVs) and breast cancer risk.	Commun Biol	2022
34861371	European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer.	Ann Oncol	2022