Author details

Full Name

Dan L Nicolae

Affiliation

ORCID

Career Start Year

1998

Papers

140

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36638096	Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings.	PLoS Genet	2023
37571876	Epigenetic responses to rhinovirus exposure in airway epithelial cells are correlated with key transcriptional pathways in chronic rhinosinusitis.	Allergy	2023
35606880	Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.	Genome Med	2022
35615339	Estimating and accounting for unobserved covariates in high-dimensional correlated data.	Journal of the American Statistical Association	2022
34629083	Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.	Genome Med	2021
33535024	Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood.	Am J Respir Crit Care Med	2021
32997571	Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels.	Epigenetics	2021
33188283	Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma.	Commun Biol	2020
31981624	Association of HLA-DRB1â¿¿09:01 with tIgE levels among African-ancestry individuals with asthma.	J Allergy Clin Immunol	2020
34221212	ESTIMATION AND INFERENCE IN METABOLOMICS WITH NON-RANDOM MISSING DATA AND LATENT FACTORS.	Ann Appl Stat	2020
32693091	Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age.	J Allergy Clin Immunol	2020
30668570	Integrating predicted transcriptome from multiple tissues improves association detection.	PLoS Genet	2019
31754283	Accounting for unobserved covariates with varying degrees of estimability in high-dimensional biological data.	Biometrika	2019
30455414	Assembly of a pan-genome from deep sequencing of 910 humans of African descent.	Nat Genet	2019
30201514	An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.	J Allergy Clin Immunol	2019
31036433	Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.	Lancet Respir Med	2019
30675526	Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree.	Commun Biol	2019
29273806	Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.	Nat Genet	2018
30358166	Gene Coexpression Networks in Whole Blood Implicate Multiple Interrelated Molecular Pathways in Obesity in People with Asthma.	Obesity (Silver Spring)	2018
30116036	Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.	Nat Genet	2018
30013184	Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.	Nat Genet	2018
30204804	Parent of origin gene expression in a founder population identifies two new candidate imprinted genes at known imprinted regions.	PLoS One	2018
29955180	Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation.	Nat Genet	2018
29307657	A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle.	J Allergy Clin Immunol	2018
29374573	Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.	J Allergy Clin Immunol	2018
29739930	Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.	Nat Commun	2018
29279374	Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.	Proc Natl Acad Sci U S A	2018
27494826	Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control.	Am J Respir Crit Care Med	2017
29180722	Rare non-coding variants are associated with plasma lipid traits in a founder population.	Sci Rep	2017
28143570	Host genetic variation in mucosal immunity pathways influences the upper airway microbiome.	Microbiome	2017
27725671	A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.	Nat Commun	2016
27147090	Association Tests for Rare Variants.	Annual Review of Genomics and Human Genetics	2016
27040689	Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx.	Am J Hum Genet	2016
27027945	Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma.	Ann Am Thorac Soc	2016
26399222	Genetic associations with viral respiratory illnesses and asthma control inÂ children.	Clin Exp Allergy	2016
26474238	Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways.	Am J Respir Crit Care Med	2016
26496228	A unified set-based test with adaptive filtering for gene-environment interaction analyses.	Biometrics	2016
27942592	DNA methylation in lung cells is associated with asthma endotypes and genetic risk.	JCI Insight	2016
27835642	Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.	PLoS Genet	2016
26258848	A gene-based association method for mapping traits using reference transcriptome data.	Nat Genet	2015
25591454	Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma.	Nat Commun	2015
25918834	Stress and Bronchodilator Response in Children with Asthma.	Am J Respir Crit Care Med	2015
25488688	Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos.	J Allergy Clin Immunol	2015
25735005	PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population.	PLoS Comput Biol	2015
25763605	Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma.	Am J Respir Crit Care Med	2015
25935106	Genome-wide association study of recalcitrant atopic dermatitis in Korean children.	J Allergy Clin Immunol	2015
24824216	Genome-wide interaction studies reveal sex-specific asthma risk alleles.	Hum Mol Genet	2014
23932459	Genome-wide association study of lung function phenotypes in a founder population.	J Allergy Clin Immunol	2014
24018621	Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans.	Pharmacogenomics J	2014
24493630	A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.	Cancer Epidemiol Biomarkers Prev	2014