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Author Details

Ximena Barros-??lvarez
Stanford University School of Medicine
2011
17
11
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35241813The oxytocin signaling complex reveals a molecular switch for cation dependence.Nat Struct Mol Biol2022
35418682The tethered peptide activation mechanism of adhesion GPCRs.Nature2022
36171289Bespoke library docking for 5-HT<sub>2A</sub> receptor agonists with antidepressant activity.Nature2022
36087581Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.Neuron2022
34194039G-protein activation by a metabotropic glutamate receptor.Nature2021
33479683Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against <i>Trypanosoma brucei</i>.RSC Med Chem2020
29633973The crystal structure of the drug target Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with a catalytic intermediate.Acta Crystallogr F Struct Biol Commun2018
28848016Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections.Antimicrob Agents Chemother2017
28465105Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors.Bioorg Med Chem Lett2017
28110521From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis.ACS Infect Dis2017
28427904Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.Biochimie2017
27788467Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors.Eur J Med Chem2016
25917939The glycosomal-membrane associated phosphoglycerate kinase isoenzyme A plays a role in sustaining the glucose flux in Trypanosoma cruzi epimastigotes.Mol Biochem Parasitol2015
23834165Glycosomal targets for anti-trypanosomatid drug discovery.Curr Med Chem2014
24858924The phosphoglycerate kinase isoenzymes have distinct roles in the regulation of carbohydrate metabolism in Trypanosoma cruzi.Exp Parasitol2014
23553092Learning together to work together: interprofessional education for students in a primary care setting in chile.Fam Med2013
21272581Leishmania mexicana: LACK (Leishmania homolog of receptors for activated C-kinase) is a plasminogen binding protein.Exp Parasitol2011
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Collaborators

Frederick S Buckner
University of Washington
Co-authored papers 7
Christophe L M J Verlinde
University of Washington
Co-authored papers 6
Georgios Skiniotis
Stanford University School of Medicine
Co-authored papers 5
Michael J Robertson
Stanford University School of Medicine
Co-authored papers 5
Alpay B Seven
Stanford University School of Medicine
Co-authored papers 4
Sayaka Shibata
Co-authored papers 4
Justin G Meyerowitz
Co-authored papers 3
Kuglae Kim
University of North Carolina School of Medicine
Co-authored papers 2
Bryan L Roth
UNC Chapel Hill School of Medicine
Co-authored papers 2
Carl-Mikael Suomivuori
Stanford University School of Medicine
Co-authored papers 1
Marc A D??mgen
Stanford University
Co-authored papers 1
Brian E Krumm
University of North Carolina School of Medicine
Co-authored papers 1
Jeffrey F DiBerto
University of North Carolina at Chapel Hill
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Ron O Dror
Co-authored papers 1
Ruth H??ttenhain
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 1
Brian K Shoichet
Department of Pharmaceutical Chemistry, University of California san francisco
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Can Cao
University of North Carolina School of Medicine
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Xi-Ping Huang
University of North Carolina School of Medicine
Co-authored papers 1
John J Irwin
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Shicheng Zhang
University of North Carolina at Chapel Hill
Co-authored papers 1
Ouliana Panova
Stanford University School of Medicine, Stanford University
Co-authored papers 1
Jonathan F Fay
University of North Carolina School of Medicine
Co-authored papers 1
Ryan H Gumpper
UNC School of Medicine
Co-authored papers 1
Xiaofang Zhong
School of Pharmacy, University of Wisconsin-Madison
Co-authored papers 1
David E Nichols
Eshelman School of Pharmacy, University of North Carolina
Co-authored papers 1
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