Author details

Full Name

Charles Kooperberg

Affiliation

ORCID

Career Start Year

1991

Papers

425

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36721044	An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling.	Commun Biol	2023
36444934	Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease.	Hum Mol Genet	2023
36116031	An empirical Bayes approach to improving population-specific genetic association estimation by leveraging cross-population data.	Genetic Epidemiology	2023
37756531	Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk.	Diabetes Care	2023
37601974	Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries.	Cell Genom	2023
37841955	A Type 1 Diabetes Polygenic Score Is Not Associated With Prevalent Type 2 Diabetes in Large Population Studies.	J Endocr Soc	2023
37745480	Whole Genome Sequencing Based Analysis of Inflammation Biomarkers in the Trans-Omics for Precision Medicine (TOPMed) Consortium.	bioRxiv	2023
37662265	WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.	medRxiv	2023
37658231	Assessing efficiency of fine-mapping obesity-associated variants through leveraging ancestry architecture and functional annotation using PAGE and UKBB cohorts.	Hum Genet	2023
37648373	Ancestral diversity in lipoprotein(a) studies helps address evidence gaps.	Open Heart	2023
37804200	Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.	J Am Heart Assoc	2023
37986948	Genome-Wide Interaction Analysis with DASH Diet Score Identified Novel Loci for Systolic Blood Pressure.	medRxiv	2023
37802043	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.	Am J Hum Genet	2023
38076909	Evidence of survival bias in the association between and age of ischemic stroke onset.		2023
37875120	Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics.	Am J Hum Genet	2023
38061917	Individual and Neighborhood-level Socioeconomic Status and Somatic Mutations Associated With Increased Risk of Cardiovascular Disease and Mortality: A Cross-Sectional Analysis in the Women's Health Initiative.		2023
37777527	Deleterious heteroplasmic mitochondrial mutations are associated with an increased risk of overall and cancer-specific mortality.	Nat Commun	2023
37961350	A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies.	bioRxiv	2023
37348055	Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants.	Genetics	2023
37090648	MUSSEL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups.	bioRxiv	2023
37034613	Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric Disorders.	Res Sq	2023
37034583	Metabolomic Evaluation of Air Pollution-related Bone Damage and Potential Mediation.	Res Sq	2023
36778406	Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants.	bioRxiv	2023
37210288	Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights.	Eur Urol	2023
37148359	The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.	Diabetologia	2023
37466697	Associations between Ambient Air Pollutants and Clonal Hematopoiesis of Indeterminate Potential.	Cancer Epidemiol Biomarkers Prev	2023
37333361	Association of Clonal Hematopoiesis of Indeterminate Potential with Incident Heart Failure with Preserved Ejection Fraction.		2023
36960714	Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program.	Circ Genom Precis Med	2023
36895838	Pregnancy loss and risk of incident CVD within 5 years: Findings from the Women's Health Initiative.	Front Cardiovasc Med	2023
36824751	Genetic mechanisms of 184 neuro-related proteins in human plasma.	medRxiv	2023
37398003	Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.	medRxiv	2023
37268629	Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups.	Nat Commun	2023
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
37131817	Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics.	bioRxiv	2023
37126548	The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.	Sci Adv	2023
36941441	Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals.	Nat Genet	2023
37046083	Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.	Nature	2023
36930136	Cardiovascular Disease and Mortality inÂ Black Women Carrying the Amyloidogenic V122I Transthyretin GeneÂ Variant.		2023
36791419	Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits.	Diabetes	2023
36539618	Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.	Nat Genet	2023
37425772	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study.	medRxiv	2023
36918541	Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.	Nat Commun	2023
37533140	Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait.	Clin J Am Soc Nephrol	2023
37489536	Age at Menopause, Leukocyte Telomere Length, and Coronary Artery Disease in Postmenopausal Women.		2023
37546893	Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus.	medRxiv	2023
37351909	Genetic Susceptibility to Nonalcoholic Fatty Liver Disease and Risk for Pancreatic Cancer: Mendelian Randomization.	Cancer Epidemiol Biomarkers Prev	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
36782065	Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.	Nat Genet	2023
35263625	Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits.	Am J Hum Genet	2022
36180445	Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.	Nat Commun	2022