Author details

Full Name

Anna C Schinzel

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34810201	Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer.	Cancer Res	2022
30777879	MCL1 and DEDD Promote Urothelial Carcinoma Progression.	Mol Cancer Res	2019
31727771	The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.	Genes Dev	2019
27899381	Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6.	Cancer Res	2017
28447610	PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.	Nat Commun	2017
28607496	Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.	Nat Commun	2017
24909179	PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling.	Oncogene	2015
25535366	An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma.	Proc Natl Acad Sci U S A	2015
26499495	Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma.	Elife	2015
24747640	Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.	Nat Genet	2014
24444711	Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.	Cancer Discov	2014
24954536	KRAS and YAP1 converge to regulate EMT and tumor survival.	Cell	2014
23322301	Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.	Genes Dev	2013
23764425	Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.	Cancer Discov	2013
23245941	Î²-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.	Cell	2012
22730461	Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.	Proc Natl Acad Sci U S A	2012
22684105	Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells.	J Clin Invest	2012
22326953	The intersection of genetic and chemical genomic screens identifies GSK-3Î± as a target in human acute myeloid leukemia.	J Clin Invest	2012
21889194	BET bromodomain inhibition as a therapeutic strategy to target c-Myc.	Cell	2011
21430775	Initial genome sequencing and analysis of multiple myeloma.	Nature	2011
20126544	CK1epsilon is required for breast cancers dependent on beta-catenin activity.	PLoS One	2010
20227043	An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.	Cancer Cell	2010
19847166	Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.	Nature	2009
19364473	Integrative genomic approaches to understanding cancer.	Biochim Biophys Acta	2009
19182807	The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.	Nature Immunology	2009
19490892	Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.	Cell	2009
19573809	AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.	Cancer Cell	2009
19800574	Proteomic and genetic approaches identify Syk as an AML target.	Cancer Cell	2009
17981529	Oncogenic transformation and experimental models of human cancer.	Front Biosci	2008
16645094	RETRACTED: Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.	Science	2006
16103352	Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.	Proceedings of the National Academy of Sciences of the United States of America	2005
15037603	Conformational control of Bax localization and apoptotic activity by Pro168.	Journal of Cell Biology	2004
14996494	Bcl-2 family members: integrators of survival and death signals in physiology and pathology [corrected].		2004
14729175	Bcl-w(edding) with mitochondria.	Trends in Cell Biology	2004