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Author Details

Rasmus Hartmann-Petersen
University of Copenhagen
1998
141
43
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36758042Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen® FFPE BRAF qPCR assay.PLoS One2023
37160462Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components.Cell Mol Life Sci2023
37443362Discovering functionally important sites in proteins.Nat Commun2023
36976271Rare Catechol-<i>O</i>-methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets.Biochemistry2023
37463013Phosphorylation of Schizosaccharomyces pombe Dss1 mediates direct binding to the ubiquitin-ligase Dma1 in vitro.Protein Sci2023
37292969Characterizing glucokinase variant mechanisms using a multiplexed abundance assay.bioRxiv2023
36609589HSP70-binding motifs function as protein quality control degrons.Cell Mol Life Sci2023
36434153Lynch syndrome, molecular mechanisms and variant classification.Br J Cancer2023
36495918Prediction of Quality-control Degradation Signals in Yeast Proteins.J Mol Biol2023
36863450The moonlighting of RAD23 in DNA repair and protein degradation.Biochim Biophys Acta Gene Regul Mech2023
35974206A context-dependent and disordered ubiquitin-binding motif.Cell Mol Life Sci2022
35700725Disease-linked mutations cause exposure of a protein quality control degron.Structure2022
3640017114-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes.Diabetes Res Clin Pract2022
36481666Conserved degronome features governing quality control associated proteolysis.Nat Commun2022
36350035How phosphorylation impacts intrinsically disordered proteins and their function.Essays Biochem2022
34166445A new sensitive and fast assay for the detection of EGFR mutations in liquid biopsies.PLoS One2021
33779753Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance.Mol Biol Evol2021
33886538Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition.PLoS Genet2021
33914734Mapping the degradation pathway of a disease-linked aspartoacylase variant.PLoS Genet2021
34750429Adipose MDM2 regulates systemic insulin sensitivity.Sci Rep2021
34272906The disordered PCI-binding human proteins CSNAP and DSS1 have diverged in structure and function.Protein Sci2021
31449985Novel HARS2 missense variants identified in individuals with sensorineural hearing impairment and Perrault syndrome.Eur J Med Genet2020
33137092Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation.PLoS Genet2020
32759676Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome.Biomolecules2020
32142608Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water.ACS Synth Biol2020
29470691Even effect of milk protein and carbohydrate intake but no further effect of heavy resistance exercise on myofibrillar protein synthesis in older men.Eur J Nutr2019
31697235Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome.Elife2019
31213625Water dynamics in MCF-7 breast cancer cells: a neutron scattering descriptive study.Sci Rep2019
30712981Biophysical and Mechanistic Models for Disease-Causing Protein Variants.Trends Biochem Sci2019
30635086Protein stability and degradation in health and disease.Adv Protein Chem Struct Biol2019
30648773Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations.Hum Mutat2019
29111377Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function.Neurochem Int2018
30230310Random Mutagenesis Analysis of the Influenza A M2 Proton Channel Reveals Novel Resistance Mutants.Biochemistry2018
30355493Expanded Interactome of the Intrinsically Disordered Protein Dss1.Cell Rep2018
28065793Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites.Neurochem Int2017
28245241Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists.PLoS One2017
28422960Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations.PLoS Genet2017
28779490Blocking protein quality control to counter hereditary cancers.Genes Chromosomes Cancer2017
28765280The exocyst subunit Sec3 is regulated by a protein quality control pathway.J Biol Chem2017
27966061UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1.Cell Stress Chaperones2017
26944332DSS1/Sem1, a Multifunctional and Intrinsically Disordered Protein.Trends Biochem Sci2016
26507541Macronutrient composition determines accumulation of persistent organic pollutants from dietary exposure in adipose tissue of mice.J Nutr Biochem2016
26578713p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.Am J Physiol Endocrinol Metab2016
27613054High-Throughput siRNA Screening Applied to the Ubiquitin-Proteasome System.Methods Mol Biol2016
27497779No effect of anti-inflammatory medication on postprandial and postexercise muscle protein synthesis in elderly men with slightly elevated systemic inflammation.Exp Gerontol2016
26966660Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases.PeerJ2016
26709791The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove.Front Biosci (Landmark Ed)2016
26708109Design and synthesis of novel Y-shaped barbituric acid derivatives as PPARγ activators.Eur J Med Chem2016
26703188The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects.Prog Lipid Res2016
27026084Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice.Am J Physiol Endocrinol Metab2016
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Collaborators

Clinical and Health Sciences, University of South Australia
Co-authored papers 17
University of Copenhagen
Co-authored papers 16
Institute of Biochemistry and Molecular Biology, University of Freiburg
Co-authored papers 13
University of Copenhagen
Co-authored papers 9
Institute of Genetics and Cancer, University of Edinburgh
Co-authored papers 6
University of Washington, USA Brotman Baty Institute for Precision Medicine
Co-authored papers 2
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 2
Institute of Cell Biology, University of Edinburgh
Co-authored papers 1
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Co-authored papers 1
Co-authored papers 1
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 1
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of California Davis
Co-authored papers 1
The University of Edinburgh
Co-authored papers 1
Translational and Clinical Research Institute, Newcastle University
Co-authored papers 1
Co-authored papers 1
Expert Systems Inc.
Co-authored papers 1
Co-authored papers 1
University of Zurich
Co-authored papers 1
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Co-authored papers 1
Heinrich-Heine-Universitat Dusseldorf
Co-authored papers 1
The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 1
Institute of Functional Microbial Genomics, Heinrich-Heine-University
Co-authored papers 1
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University of Toronto
Co-authored papers 1
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