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Author Details

Aldons J Lusis
1973
733
129
PMIDPaper TitleJournal TitlePublished Year
37495690Mammary duct luminal epithelium controls adipocyte thermogenic programme.Nature2023
37923961A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.Commun Biol2023
38008808Gene Regulatory Networks in Coronary Artery Disease.2023
38060277Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse.Elife2023
37962168Systems genetics approaches for understanding complex traits with relevance for human disease.Elife2023
37611662Role of Matrix Gla Protein in Transforming Growth Factor-β Signaling and Nonalcoholic Steatohepatitis in Mice.Cell Mol Gastroenterol Hepatol2023
36973420Author Correction: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.Nat Microbiol2023
37279756Gut bacterial metabolism contributes to host global purine homeostasis.Cell Host Microbe2023
37333408Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse.bioRxiv2023
36880999Intestinal cell type-specific communication networks underlie homeostasis and response to Western diet.2023
36759753Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.Nat Microbiol2023
36806709MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis.2023
36747758Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD.bioRxiv2023
37178122Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice.Cell Rep2023
37230214Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD.Metabolism2023
35121757Placental genomics mediates genetic associations with complex health traits and disease.Nat Commun2022
35504280Atherosclerosis: Recent developments.Cell2022
35381883Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.Basic Res Cardiol2022
35628290Oxy210, a Semi-Synthetic Oxysterol, Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization.International Journal of Molecular Sciences2022
35377742Identification of DNA Damage Repair Enzyme as Causal for Heart Failure With Preserved Ejection Fraction.Circulation2022
36276926A mechanistic framework for cardiometabolic and coronary artery diseases.Nat Cardiovasc Res2022
36144244Identification of the Transcription Factor ATF3 as a Direct and Indirect Regulator of the LDLR.Metabolites2022
36333379Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.Nat Commun2022
36137043Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure.Science2022
35870705Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach.Molecular Metabolism2022
35797133Altered branched-chain α-keto acid metabolism is a feature of NAFLD in individuals with severe obesity.JCI Insight2022
35787630Sex differences in heart mitochondria regulate diastolic dysfunction.Nature Communications2022
36513961Coagulation factor with potential for the treatment of heart failure.2022
36472367Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function.Elife2022
34847077β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity.J Clin Invest2022
35175464Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.Basic Res Cardiol2022
34813507Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.J Clin Invest2022
35072627Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.eLife2022
34697471Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.Nature Metabolism2021
33594006Machine Learning Reveals Time-Varying Microbial Predictors with Complex Effects on Glucose Regulation.mSystems2021
33591957Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle.Journal of Clinical Investigation2021
33483510An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.Nat Commun2021
34233476Genome-Wide Association Study Identifies a Functional Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease.Arteriosclerosis, Thrombosis, and Vascular Biology2021
34011630ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.Science Translational Medicine2021
33532862Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.Eur Heart J2021
33626882Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism.Circulation2021
33626337Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.Am J Hum Genet2021
33462485Large-scale association analyses identify host factors influencing human gut microbiome composition.Nat Genet2021
33667465Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection.Journal of Lipid Research2021
33667367A vicious cycle in atherosclerosis.Cell2021
33665512Loop Diuretics Inhibit Renal Excretion of Trimethylamine -Oxide.JACC: Basic to Translational Science2021
33761762Sexually Dimorphic Relationships Among Saa3 (Serum Amyloid A3), Inflammation, and Cholesterol Metabolism Modulate Atherosclerosis in Mice.Arteriosclerosis, Thrombosis, and Vascular Biology2021
33436815Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice.Sci Rep2021
33086870Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis.Arteriosclerosis, Thrombosis, and Vascular Biology2021
32866618The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice.Cell Mol Gastroenterol Hepatol2021
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